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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for 21c Museum Hotel hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,019 reviews)
"The staff was super friendly and the location was perfect!"
United States
Lateshia
The price is ฿3,692
฿4,343 total
includes taxes & fees
10 Aug - 11 Aug
Homewood Suites by Hilton Louisville Downtown, KY
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,010 reviews)
"Great place to stay!"
United States
Jennifer
The price is ฿5,468
฿6,434 total
includes taxes & fees
2 Aug - 3 Aug
The Grady
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,009 reviews)
"Beautiful property, on-site restaurant was delicious. Beds very nice."
United States
nicolle
The price is ฿5,959
฿7,178 total
includes taxes & fees
2 Aug - 3 Aug
21c Museum Hotel Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (482 reviews)
"Great hotel and great staff."
United States
Jasmine
The price is ฿6,709
฿7,894 total
includes taxes & fees
2 Aug - 3 Aug
Hotel Distil, Autograph Collection
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,989 reviews)
"Beautiful, clean property with many things to do at and around the hotel."
United States
Brittany
The price is ฿5,300
฿6,236 total
includes taxes & fees
2 Aug - 3 Aug
Omni Louisville Hotel
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (668 reviews)
"The front desk and breakfast staff were very friendly and helpful. After a long drive with family, this hotel was a great choice and I would definitely recommend it."
United States
Nibu
The price is ฿3,795
฿4,466 total
includes taxes & fees
30 Jul - 31 Jul
Towneplace Suites By Marriott Louisville Downtown
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,010 reviews)
"Clean, spacious and close to the things we wanted to do"
United States
John
The price is ฿3,303
฿3,886 total
includes taxes & fees
3 Aug - 4 Aug
Cambria Hotel Louisville Downtown-Whiskey Row
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (121 reviews)
"Great place near quite a few shops and restaurants. Close enough to downtown. Breakfast was nice and everyone was very welcoming."
United States
Anissa
The price is ฿5,551
฿6,273 total
includes taxes & fees
14 Jul - 15 Jul
Market Street Inn
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (126 reviews)
"Great stay"
United States
Kristen
The price is ฿5,706
฿6,713 total
includes taxes & fees
2 Aug - 3 Aug
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
10.0 out of 10, Exceptional, (24 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is ฿10,321
฿11,979 total
includes taxes & fees
15 Jul - 16 Jul
Louisville Bourbon Inn
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,277 reviews)
"Nice staff, large room"
United States
Lisa
The price is ฿5,124
฿6,029 total
includes taxes & fees
4 Aug - 5 Aug
The Brown Hotel
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (797 reviews)
"Great and fun spot! Enjoyed our one night here"
United States
Adam
The price is ฿3,462
฿4,074 total
includes taxes & fees
26 Jul - 27 Jul
Moxy Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (139 reviews)
"I had a great stay at Stellar Suites. Two quick nights in a very comfortable suite was exactly what was needed. Superior location and very responsive hosts. I’ll be sure and stay here the next time I’m in the area."
United States
Dustin
The price is ฿3,375
฿5,656 total
includes taxes & fees
14 Jul - 15 Jul
Stellar Suites
2 restaurants; breakfast and dinner served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,062 reviews)
"Excellent location and clean hotel!"
United States
Monica
The price is ฿4,068
฿4,786 total
includes taxes & fees
26 Jul - 27 Jul
Tempo By Hilton Louisville Downtown Nulu
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,749 reviews)
"Wonderful location, very nice hotel with great amenities"
United States
Astrid
The price is ฿2,921
฿3,437 total
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Louisville Downtown by IHG
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,293 reviews)
"Well kept and the staff was very knowledgeable and helpful."
United States
Patricia
The price is ฿4,870
฿5,730 total
includes taxes & fees
31 Jul - 1 Aug
Embassy Suites Louisville Downtown
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
2.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (136 reviews)
"Unique rooms Excellent breakfast"
United States
Annette
The price is ฿4,755
฿5,519 total
includes taxes & fees
29 Jul - 30 Jul
DuPont Mansion Bed & Breakfast
Restaurant

Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,015 reviews)
"great location, clean and pleasant staff"
United States
Margarita
The price is ฿4,256
฿5,007 total
includes taxes & fees
3 Aug - 4 Aug
Aloft by Marriott Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,003 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is ฿5,698
฿6,704 total
includes taxes & fees
9 Aug - 10 Aug
Louisville Marriott Downtown
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (675 reviews)
"Great location with a clean and comfortable room."
United States
David
The price is ฿3,811
฿4,484 total
includes taxes & fees
19 Jul - 20 Jul
AC Hotel Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,019 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,010 reviews
View
Front of property
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,009 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
482 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
1,989 reviews
View

Top 21c Museum Hotel Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"We had an amazing stay! From the moment we arrived, the staff made us feel so welcome and went above and beyond to ensure we had everything we needed. The hotel was spotless, beautifully maintained, and the room was comfortable, spacious, and very clean! The location was perfect, making it easy to get everywhere we wanted to go. We especially appreciated the attention to detail and the excellent customer service throughout our stay. Thank you for making our trip so enjoyable. We truly felt at home and can't wait to come back. I highly recommend this hotel to anyone looking for a relaxing, comfortable, and memorable stay!"
Zulaika 2-night trip
Posted 8 hours ago
The Brown Hotel

Hotels near other 21c Museum Hotel attractions

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 227 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Homewood Suites by Hilton Louisville Downtown, KY.
How many hotels are there near 21c Museum Hotel?
Expedia has 227 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.