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Check prices for these dates

Tonight
20 Jan - 21 Jan
Tomorrow
21 Jan - 22 Jan
This weekend
23 Jan - 25 Jan
Next weekend
30 Jan - 1 Feb

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Our top choices for 21c Museum Hotel hotels

Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,001 reviews)
"Location and the staff was fabulous."
United States
Madeline
The price is ฿4,384
฿5,314 total
includes taxes & fees
25 Jan - 26 Jan
21c Museum Hotel Louisville
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,003 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is ฿4,529
฿5,328 total
includes taxes & fees
1 Feb - 2 Feb
The Grady
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
10.0 out of 10, Exceptional, (20 reviews)
"Great breakfast. Frittata, French toast, eggs, bacon, sausage, grapes, toast, biscuits and gravy - all were excellent. "
United States
Gaven
The price is ฿8,282
฿9,613 total
includes taxes & fees
21 Jan - 22 Jan
Louisville Bourbon Inn
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (120 reviews)
"We’ve stayed at this beautiful B&B twice. The location, charm, cleanliness, and staff make it an absolute treasure."
United States
Austin
The price is ฿5,790
฿6,543 total
includes taxes & fees
21 Jan - 22 Jan
Market Street Inn
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (100 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is ฿4,464
฿5,181 total
includes taxes & fees
21 Jan - 22 Jan
DuPont Mansion Bed & Breakfast
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Enjoyed our stay."
United States
Christian
The price is ฿3,225
฿3,795 total
includes taxes & fees
17 Feb - 18 Feb
Cambria Hotel Louisville Downtown-Whiskey Row
Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,005 reviews)
"Very friendly and clean! Great stay! "
United States
Jackie
The price is ฿3,306
฿3,890 total
includes taxes & fees
1 Feb - 2 Feb
Homewood Suites by Hilton Louisville Downtown, KY
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,171 reviews)
"Very beautiful facility and great location "
United States
Anthony
The Brown Hotel
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is ฿3,688
฿5,913 total
includes taxes & fees
3 Feb - 4 Feb
Stellar Suites
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (529 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is ฿3,032
฿3,567 total
includes taxes & fees
8 Feb - 9 Feb
Towneplace Suites By Marriott Louisville Downtown
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (882 reviews)
"Friendly staff, clean room, great food. "
United States
Regina
The price is ฿3,437
฿4,044 total
includes taxes & fees
5 Feb - 6 Feb
Tempo By Hilton Louisville Downtown Nulu
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,764 reviews)
"Beautiful, spacious hotel. Spotless room, kind and helpful staff."
United States
Gizella
The price is ฿5,226
฿6,149 total
includes taxes & fees
21 Jan - 22 Jan
Omni Louisville Hotel
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,005 reviews)
"Great hotel"
United States
Lazaro
The price is ฿4,193
฿4,933 total
includes taxes & fees
27 Jan - 28 Jan
Galt House Hotel Trademark Collection by Wyndham
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (67 reviews)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is ฿5,261
฿6,191 total
includes taxes & fees
27 Jan - 28 Jan
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (711 reviews)
"First time trying a moxy, will be staying with moxy hotels from now on"
United States
Robinson
The price is ฿2,782
฿3,273 total
includes taxes & fees
1 Feb - 2 Feb
Moxy Louisville Downtown
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,141 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ฿3,818
฿4,493 total
includes taxes & fees
8 Feb - 9 Feb
Embassy Suites Louisville Downtown
Exterior

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,683 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ฿2,563
฿3,015 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Louisville Downtown by IHG
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,033 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ฿3,688
฿4,339 total
includes taxes & fees
27 Jan - 28 Jan
Hotel Genevieve part of JdV by Hyatt
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,002 reviews)
"Great room and location and always a plus when pets can stay for free!"
United States
Elizabeth
The price is ฿3,141
฿3,696 total
includes taxes & fees
15 Feb - 16 Feb
Aloft Louisville Downtown
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (618 reviews)
"Everything was amazing, staff was wonderful "
United States
Ashley
The price is ฿3,564
฿4,194 total
includes taxes & fees
30 Jan - 31 Jan
AC Hotel Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top 21c Museum Hotel Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Rooms were very clean, staff was so very nice and the food at their restaurants was very good. "
Melissa 3-night trip
Posted 2 days ago
Galt House Hotel Trademark Collection by Wyndham
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

10/10 Excellent
"The staff is amazing. From valet to check in to the bartenders and servers. Everything is top notch! "
Christina 1-night trip
Posted 11 days ago
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

Louisville Science Center

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties
Kentucky Center for the Performing Arts

Kentucky Center for the Performing Arts

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 309 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.
How many hotels are there near 21c Museum Hotel?
Expedia has 309 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Thomas Edison House. You can watch performances at Kentucky Center for the Performing Arts, Louisville Palace and Derby Dinner Playhouse if you're interested in local theatre.