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Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

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Our top choices for 21c Museum Hotel hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,000 reviews)
"Had a great stay! "
United States
Amanda
The price is ฿4,180
฿4,918 total
includes taxes & fees
21 Jun - 22 Jun
Homewood Suites by Hilton Louisville Downtown, KY
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,005 reviews)
"Had a wonderful stay and the staff were so friendly!"
United States
Tanya
The price is ฿6,060
฿7,130 total
includes taxes & fees
14 Jun - 15 Jun
The Grady
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (612 reviews)
"Great place to stay! I would definitely stay here again!"
United States
Dana Jean
The price is ฿3,726
฿4,384 total
includes taxes & fees
31 May - 1 Jun
Towneplace Suites By Marriott Louisville Downtown
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (121 reviews)
"Great place near quite a few shops and restaurants. Close enough to downtown. Breakfast was nice and everyone was very welcoming."
United States
Anissa
The price is ฿5,413
฿6,117 total
includes taxes & fees
8 Jun - 9 Jun
Market Street Inn
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,889 reviews)
"Great place to stay, perfect location "
United States
Ben
The price is ฿6,249
฿7,353 total
includes taxes & fees
1 Jun - 2 Jun
Omni Louisville Hotel
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
10.0 out of 10, Exceptional, (24 reviews)
"The property is beautiful. Our room was lovely—very clean and comfortable. The seating in our room was perfect for reading, and the balcony an extra treat. Allen was so gracious and helpful. The location was great for dinner plans and a short easy drive to Churchill Downs. Breakfast was delicious—especially the biscuits and gravy. And, the young lady that served us breakfast was very nice and helpful. I’d recommend this Bed and Breakfast to anyone who is planning to spend time in...
United States
Nancy
The price is ฿10,064
฿11,681 total
includes taxes & fees
8 Jun - 9 Jun
Louisville Bourbon Inn
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,011 reviews)
"Loved our stay!"
United States
Rebecca
The price is ฿4,073
฿4,792 total
includes taxes & fees
31 May - 1 Jun
Cambria Hotel Louisville Downtown-Whiskey Row
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,230 reviews)
"Breakfast menu was great, bartender, and drinks were wonderful!"
United States
hannah
The price is ฿6,738
฿7,928 total
includes taxes & fees
20 Jun - 21 Jun
The Brown Hotel
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (135 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is ฿3,508
฿5,779 total
includes taxes & fees
2 Jun - 3 Jun
Stellar Suites
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (761 reviews)
"The Moxy is a great hotel, very cool decor. Great location and a very helpful staff. Rooms are quiet and there is a nice bar in the lobby."
United States
Carrie
The price is ฿2,909
฿3,423 total
includes taxes & fees
21 Jun - 22 Jun
Moxy Louisville Downtown
4 restaurants; breakfast, lunch, and dinner served

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,169 reviews)
"The staff was super friendly and the stay was very comfortable!"
United States
James
The price is ฿5,296
฿6,232 total
includes taxes & fees
6 Jun - 7 Jun
Galt House Hotel Trademark Collection by Wyndham
2 restaurants; breakfast and dinner served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,023 reviews)
"Excellent location and clean hotel!"
United States
Monica
The price is ฿4,417
฿5,197 total
includes taxes & fees
14 Jun - 15 Jun
Tempo By Hilton Louisville Downtown Nulu
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,251 reviews)
"Clean, great staff!"
United States
Natali
The price is ฿3,811
฿4,484 total
includes taxes & fees
14 Jun - 15 Jun
Embassy Suites Louisville Downtown
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
2.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (123 reviews)
"The staff and breakfast served was excellent. Amazing time, I will come back next time!!"
United States
Raman
The price is ฿4,637
฿5,382 total
includes taxes & fees
7 Jun - 8 Jun
DuPont Mansion Bed & Breakfast
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,734 reviews)
"Room was clean, staff was helpful and breakfast was excellent"
United States
Chic
The price is ฿3,279
฿3,858 total
includes taxes & fees
9 Jun - 10 Jun
Holiday Inn Express & Suites Louisville Downtown by IHG
Restaurant

Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location right on Whiskey Row. Easy walk to lots of fun destinations."
United States
KIMBERLI
The price is ฿4,178
฿4,915 total
includes taxes & fees
21 Jun - 22 Jun
Aloft by Marriott Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,000 reviews)
"Bar was great."
United Kingdom
Pete
The price is ฿5,875
฿6,912 total
includes taxes & fees
21 Jun - 22 Jun
Louisville Marriott Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,094 reviews)
"Adorable rooms and great spaces in the lobby to work. "
United States
Marissa
The price is ฿4,383
฿5,157 total
includes taxes & fees
7 Jun - 8 Jun
Hotel Genevieve part of JdV by Hyatt
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (657 reviews)
"Great staff"
United States
paulin
The price is ฿3,976
฿4,678 total
includes taxes & fees
31 May - 1 Jun
AC Hotel Louisville Downtown
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 0.6 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel is perfectly located and the amenities are great!"
United States
Marcus
The price is ฿5,197
฿6,114 total
includes taxes & fees
26 Jun - 27 Jun
Hyatt Regency Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,000 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,005 reviews
View
Property amenity
Towneplace Suites By Marriott Louisville Downtown
3.0 star property
9.2
Wonderful
612 reviews
View
Interior entrance
Market Street Inn
3.5 star property
9.8
Exceptional
121 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
1,889 reviews
View

Top 21c Museum Hotel Hotel Reviews

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

6/10 Okay
"Had to ask for a room service menu which came on a door hanger Shortage of baggage carts Closet hangers only had lower row No place to hang long dresses, outdated tub and shower combo Dropoff at front of hotel overwhelmed by two weddings with deliveries and guests trying to valet park - told it was normal Bar great if a bourbon drinker - not so much if you wanted johnny walker, mccallan, oban, glenmorangie - not even a listing on the drinks menu of scotch that was available No variety on breakfast menu. Try some corn beef hash, ham, shredded hash browns, sausage that was not overcooked and dried out, crisp bacon Far below expectations for a hilton"
Robert 3-night trip
Posted 1 hour ago
Seelbach Hilton Louisville Downtown

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

3.9/5 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 268 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Homewood Suites by Hilton Louisville Downtown, KY.
How many hotels are there near 21c Museum Hotel?
Expedia has 268 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.