The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Check prices for these dates

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30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (25 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is ฿9,420
฿10,934 total
includes taxes & fees
9 Nov - 10 Nov
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.

2. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is ฿7,466
฿8,437 total
includes taxes & fees
28 Oct - 29 Oct
Market Street Inn
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.6 out of 10, Exceptional, (150 reviews)
"5 STAR B&B"
United States
Casey
The price is ฿4,824
฿5,600 total
includes taxes & fees
1 Nov - 2 Nov
DuPont Mansion Bed & Breakfast
A grand lobby with ornate columns, plush seating, and a chandelier.

4. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,435 reviews)
"We had a nice stay!"
United States
katisha
The price is ฿4,026
฿4,737 total
includes taxes & fees
25 Nov - 26 Nov
The Brown Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,006 reviews)
"Staff very friendly"
United States
peter
The price is ฿3,850
฿4,530 total
includes taxes & fees
24 Nov - 25 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

6. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (2,208 reviews)
"Beautiful Hotel"
United States
Kristan
The price is ฿6,861
฿8,072 total
includes taxes & fees
21 Nov - 22 Nov
Omni Louisville Hotel
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,006 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is ฿5,259
฿6,187 total
includes taxes & fees
15 Nov - 16 Nov
The Grady
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

8. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (156 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is ฿3,905
฿6,296 total
includes taxes & fees
9 Nov - 10 Nov
Stellar Suites
A classical gold statue in front of a multi-story building with large windows and a brick facade.

9. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,008 reviews)
"It was a great stay! The room and location were perfect, and the staff were very accommodating!"
United States
Matt
The price is ฿5,137
฿6,213 total
includes taxes & fees
18 Nov - 19 Nov
21c Museum Hotel Louisville
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

10. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,144 reviews)
"Great stay!"
United States
Addison
The price is ฿3,434
฿4,041 total
includes taxes & fees
25 Nov - 26 Nov
Tempo By Hilton Louisville Downtown Nulu
A modern bar area with a circular bar, multiple seating options, and a large screen.

11. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,008 reviews)
"Location was perfect and staff was very friendly."
United States
Sarah
The price is ฿3,216
฿3,783 total
includes taxes & fees
22 Nov - 23 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
A brick building with outdoor seating and a fire pit.

12. TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (745 reviews)
"Room was clean, breakfast was good, great walkable location with onsite free parking!"
United States
Lori M
The price is ฿3,783
฿4,275 total
includes taxes & fees
24 Nov - 25 Nov
TownePlace Suites by Marriott Louisville North
A covered patio with a stone wall, a glass table, and a bench.

13. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Louisville Science Center
9.2 out of 10, Wonderful, (99 reviews)
"Beautiful 1880’s mansion converted to bed & breakfast. Gorgeous stained glass windows, fireplaces. Innkeeper was super friendly and accommodating/ lives onsite which is very convenient. Hearty and flavorful breakfast. Amazing neighborhood full of beautiful late 1800’s homes. Wish we had more time to explore Olde Louisville"
United States
Nicole
The price is ฿5,766
฿6,693 total
includes taxes & fees
2 Nov - 3 Nov
Central Park Bed & Breakfast
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

14. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,097 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is ฿4,560
฿5,365 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

15. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,007 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ฿4,132
฿4,861 total
includes taxes & fees
23 Nov - 24 Nov
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

16. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is ฿4,053
฿4,769 total
includes taxes & fees
15 Nov - 16 Nov
Moxy Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

17. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,447 reviews)
"Great place to stay!!!"
United States
Shun
The price is ฿4,596
฿5,408 total
includes taxes & fees
8 Nov - 9 Nov
Galt House Hotel Trademark Collection by Wyndham
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

18. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (728 reviews)
"Great stay"
United States
Jen
The price is ฿4,832
฿5,685 total
includes taxes & fees
6 Nov - 7 Nov
AC Hotel Louisville Downtown
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

19. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,388 reviews)
"Excellent stay"
United States
Frances
The price is ฿4,127
฿4,856 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

20. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,010 reviews)
"Great place"
United States
MILTON
The price is ฿4,278
฿5,033 total
includes taxes & fees
27 Nov - 28 Nov
Louisville Marriott Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
4.0 star property
9.6
Exceptional
150 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,435 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,006 reviews
View

Top Louisville Science Center Hotel Reviews

Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

10/10 Excellent
"The walk to KFC Yum Center is close and easily doable,"
Nicholas 1-night trip
Posted less than an hour ago
Holiday Inn Louisville Downtown by IHG

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.