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Our top choices for Louisville Science Center hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Beautiful pristine accommodation … great swim next morning before delicious breakfast designed for all tastes… all in all a wonderful treat!"
United States
BRENDA
The price is ฿3,466
฿4,078 total
includes taxes & fees
22 Mar - 23 Mar
Homewood Suites by Hilton Louisville Downtown, KY
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is ฿10,031
฿11,802 total
includes taxes & fees
26 Mar - 27 Mar
The Grady
Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Great room, super kind staff"
United States
Rachel
The price is ฿5,557
฿6,694 total
includes taxes & fees
22 Mar - 23 Mar
21c Museum Hotel Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (451 reviews)
"Great hotel & location"
United States
Ana
The price is ฿5,710
฿6,718 total
includes taxes & fees
22 Mar - 23 Mar
Hotel Distil, Autograph Collection
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (22 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is ฿8,227
฿9,549 total
includes taxes & fees
8 Mar - 9 Mar
Louisville Bourbon Inn
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (107 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is ฿4,434
฿5,147 total
includes taxes & fees
3 Mar - 4 Mar
DuPont Mansion Bed & Breakfast
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,186 reviews)
"Beautiful old hotel with a fantastic bar in the lobby"
United States
Karen
The Brown Hotel
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is ฿5,751
฿6,499 total
includes taxes & fees
3 Mar - 4 Mar
Market Street Inn
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Great stay "
United States
Sarah
The price is ฿3,331
฿3,919 total
includes taxes & fees
22 Mar - 23 Mar
Cambria Hotel Louisville Downtown-Whiskey Row
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (934 reviews)
"Always a great place to stay."
United States
Christopher
The price is ฿3,008
฿3,539 total
includes taxes & fees
8 Mar - 9 Mar
Tempo By Hilton Louisville Downtown Nulu
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (553 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is ฿3,415
฿4,018 total
includes taxes & fees
15 Mar - 16 Mar
Towneplace Suites By Marriott Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (123 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is ฿3,663
฿5,873 total
includes taxes & fees
15 Mar - 16 Mar
Stellar Suites
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (721 reviews)
"Great stay. Great location and good food. "
United States
Bryson
The price is ฿3,011
฿3,543 total
includes taxes & fees
22 Mar - 23 Mar
Moxy Louisville Downtown
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,086 reviews)
"Rooms were clean and staff were friendly! "
United States
Amy
The price is ฿3,921
฿4,613 total
includes taxes & fees
30 Mar - 31 Mar
Galt House Hotel Trademark Collection by Wyndham
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,712 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ฿2,763
฿3,251 total
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express & Suites Louisville Downtown by IHG
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,158 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ฿3,562
฿4,191 total
includes taxes & fees
8 Mar - 9 Mar
Embassy Suites Louisville Downtown
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (77 reviews)
"i love this place"
United States
THANH
The price is ฿5,320
฿6,260 total
includes taxes & fees
29 Mar - 30 Mar
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Great staff, good bar. "
United States
Edward
The price is ฿3,120
฿3,671 total
includes taxes & fees
22 Mar - 23 Mar
Aloft Louisville Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,046 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ฿4,191
฿4,931 total
includes taxes & fees
8 Mar - 9 Mar
Hotel Genevieve part of JdV by Hyatt
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (626 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is ฿3,539
฿4,164 total
includes taxes & fees
22 Mar - 23 Mar
AC Hotel Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,002 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,001 reviews
View
Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,004 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
451 reviews
View
Interior entrance
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
22 reviews
View

Top Louisville Science Center Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"Such a historic hotel! We loved our stay and can’t wait to return! "
Jessica 1-night trip
Posted 2 days ago
The Brown Hotel

Hotels near other Louisville Science Center attractions

Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!
Photo by Corey Dargan
Open Photo by Corey Dargan

Muhammad Ali Center

4.3/5 (298 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 310 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 310 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Thomas Edison House. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.