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This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for West Second Street Historic District hotels

A hot tub with a stone exterior, a patio table, and an umbrella.

1. Drew 251 Mesa

Drew 251 Mesa
3.0 star property
West Second Street Historic District
10.0 out of 10, Exceptional, (1 review)
"The house was very nice."
United States
Jeanne
The price is ฿3,736
฿13,834 total
includes taxes & fees
8 Oct - 9 Oct
Drew 251 Mesa
A hot tub with a stone exterior, a patio table, and an umbrella.

2. Drew 253 Mesa

Drew 253 Mesa
2.5 star property
West Second Street Historic District
The price is ฿3,687
฿13,779 total
includes taxes & fees
26 Oct - 27 Oct
Drew 253 Mesa
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

3. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
Mesa Grande, 3.1 km from West Second Street Historic District
9.2 out of 10, Wonderful, (2,008 reviews)
"Highly recommended nice clean place to stay"
United States
greg
The price is ฿4,508
฿5,151 total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Place Phoenix/Mesa
A hotel lobby with a reception desk, seating area, and large windows.

4. The Azure Hotel

The Azure Hotel
2.5 star property
Downtown, 1.7 km from West Second Street Historic District
8.8 out of 10, Excellent, (1,984 reviews)
"Always a good stay at this property"
United States
Heather
The price is ฿2,108
฿2,577 total
includes taxes & fees
19 Oct - 20 Oct
The Azure Hotel
A spacious dining area with multiple tables and chairs, a central counter, and a view of the outdoors through large windows.

5. Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix
3.0 star property
US 60 Corridor, 4.2 km from West Second Street Historic District
9.0 out of 10, Wonderful, (2,512 reviews)
"It was nice place to stay will stay again."
United States
Dency
The price is ฿2,394
฿2,735 total
includes taxes & fees
13 Oct - 14 Oct
Days Inn & Suites by Wyndham Mesa Near Phoenix
A modern dining area with tables and chairs, large windows, and a flat-screen TV on the wall.

6. Best Western Plus Gilbert/Mesa

Best Western Plus Gilbert/Mesa
2.5 star property
US 60 Corridor, 5.5 km from West Second Street Historic District
9.6 out of 10, Exceptional, (128 reviews)
"Very comfortable room and bed. One of the better places we have stayed."
United States
Jeffrey
The price is ฿3,258
฿3,723 total
includes taxes & fees
11 Oct - 12 Oct
Best Western Plus Gilbert/Mesa
A modern breakfast area with a sign reading "EXPRESS START BREAKFAST" and a "GOOD MORNING" sign on the wall.

7. Holiday Inn Express & Suites Phoenix - Airport North by IHG

Holiday Inn Express & Suites Phoenix - Airport North by IHG
2.5 star property
14.9 km from West Second Street Historic District
9.4 out of 10, Exceptional, (2,423 reviews)
"Great stay very convenient to the airport, would stay here again"
United States
Samuel J
The price is ฿4,075
฿4,608 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Phoenix - Airport North by IHG
A modern hotel lobby with a seating area, a staircase, and a reception desk.

8. Hampton Inn Phoenix-Airport North

Hampton Inn Phoenix-Airport North
2.5 star property
14.7 km from West Second Street Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"The continental breakfast was great and the staff were very friendly."
United States
Jodi L
The price is ฿3,140
฿3,551 total
includes taxes & fees
30 Oct - 31 Oct
Hampton Inn Phoenix-Airport North
A modern hotel with a brick facade, large windows, and a covered entrance area.

9. Springhill Suites Phoenix Scottsdale Marriott

Springhill Suites Phoenix Scottsdale Marriott
2.0 star property
10 km from West Second Street Historic District
9.4 out of 10, Exceptional, (443 reviews)
"Helpful staff and great amenities."
United States
Marie
The price is ฿4,617
฿5,262 total
includes taxes & fees
11 Oct - 12 Oct
Springhill Suites Phoenix Scottsdale Marriott
A hotel room with two beds, a desk with a chair, a TV, and a lamp.

10. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
14.2 km from West Second Street Historic District
9.2 out of 10, Wonderful, (2,035 reviews)
"Great location and a pleasant stay"
United States
William
The price is ฿3,668
฿4,182 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Scottsdale Talking Stick Entertainment District
An outdoor bar area with a modern design, featuring a counter with bar stools and a view of the interior.

11. Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University
2.5 star property
8.9 km from West Second Street Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay! I would love to stay again."
United States
Daniela
The price is ฿4,269
฿4,870 total
includes taxes & fees
15 Oct - 16 Oct
Hyatt House Tempe/Phoenix/University
A home gym with a treadmill, elliptical, and stationary bike, large windows, and a flat-screen TV.

12. City Express by Marriott Tempe

City Express by Marriott Tempe
3.0 star property
8.8 km from West Second Street Historic District
8.4 out of 10, Very good, (1,279 reviews)
"Clean and just what we needed for our quick overnight stay"
United States
Heather
The price is ฿2,867
฿3,270 total
includes taxes & fees
20 Oct - 21 Oct
City Express by Marriott Tempe
A modern hotel room with a grey sofa, a round table, a bed with white linens, a large abstract painting, a floor lamp, and a window with curtains.

13. Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
12 km from West Second Street Historic District
9.0 out of 10, Wonderful, (1,198 reviews)
"Great location..very good accommodations"
United States
dularie
The price is ฿4,269
฿4,870 total
includes taxes & fees
31 Oct - 1 Nov
Hyatt Place Tempe Phoenix Airport
A spacious lobby with a high ceiling, a central round table, seating areas, and a staircase.

14. Embassy Suites by Hilton Phoenix Tempe

Embassy Suites by Hilton Phoenix Tempe
3.5 star property
9.5 km from West Second Street Historic District
8.6 out of 10, Excellent, (1,010 reviews)
"Great place, room was nice and roomy, breakfast was great, even got 2 drink tickets for the bar. Staff was very kind."
United States
Rebecca
The price is ฿4,029
฿4,596 total
includes taxes & fees
29 Oct - 30 Oct
Embassy Suites by Hilton Phoenix Tempe
A spacious lobby with a fireplace, seating areas, and large windows.

15. Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
15.6 km from West Second Street Historic District
8.8 out of 10, Excellent, (2,810 reviews)
"Great hotel!"
United States
Aaliyah
The price is ฿4,543
฿5,137 total
includes taxes & fees
23 Oct - 24 Oct
Hilton Garden Inn Phoenix Airport North
A spacious lobby with a high ceiling, modern lighting, and a central seating area with sofas and a coffee table.

16. Hampton Inn & Suites Tempe/Phoenix Airport, AZ

Hampton Inn & Suites Tempe/Phoenix Airport, AZ
2.5 star property
12.6 km from West Second Street Historic District
9.4 out of 10, Exceptional, (1,148 reviews)
"Great location for our trip. Clean and welcoming property."
United States
JM
The price is ฿3,852
฿4,394 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites Tempe/Phoenix Airport, AZ
A hotel room with two beds, a large mirror, a TV, and a desk with a lamp.

17. Holiday Inn Express & Suites Tempe by IHG

Holiday Inn Express & Suites Tempe by IHG
2.5 star property
12.9 km from West Second Street Historic District
9.0 out of 10, Wonderful, (1,003 reviews)
"Good room clean and friendly staff"
United States
Jose A
The price is ฿3,126
฿3,566 total
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express & Suites Tempe by IHG
An outdoor seating area with sofas, chairs, and a fire pit.

18. Home2 Suites by Hilton Phoenix Airport North, AZ

Home2 Suites by Hilton Phoenix Airport North, AZ
3.0 star property
14.9 km from West Second Street Historic District
9.4 out of 10, Exceptional, (1,007 reviews)
"Staff was super friendly, the property was very clean, and the breakfast buffet was amazing."
United States
Nathan
The price is ฿3,972
฿4,491 total
includes taxes & fees
1 Nov - 2 Nov
Home2 Suites by Hilton Phoenix Airport North, AZ
A hotel room with a bed, desk, chair, and a window with curtains.

19. Country Inn & Suites by Radisson, Phoenix Airport, AZ

Country Inn & Suites by Radisson, Phoenix Airport, AZ
3.0 star property
13.6 km from West Second Street Historic District
8.4 out of 10, Very good, (3,126 reviews)
"Clean rooms and super friendly staff!"
United States
Jessica
The price is ฿3,197
฿3,614 total
includes taxes & fees
12 Oct - 13 Oct
Country Inn & Suites by Radisson, Phoenix Airport, AZ
A spacious lobby with a grand staircase, modern chandeliers, and large windows.

20. Spark by Hilton Tempe Phoenix Airport

Spark by Hilton Tempe Phoenix Airport
3.0 star property
12.6 km from West Second Street Historic District
9.2 out of 10, Wonderful, (220 reviews)
"Great stay! Highly recommend!"
United States
Lucinda
The price is ฿3,686
฿4,205 total
includes taxes & fees
1 Nov - 2 Nov
Spark by Hilton Tempe Phoenix Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in West Second Street Historic District

Find the best West Second Street Historic District areas for the activities you enjoy most.
A cityscape with prominent buildings including a Chase bank and The Arizona Republic building.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

A fountain with three horses, surrounded by red flowers and storefronts.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

A rocky hill with palm trees and a body of water.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

A mountainous landscape with a city in the valley below.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top West Second Street Historic District Hotel Reviews

Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Pools and restaurants were excellent and reasonably priced. Rooms were spacious and housekeeping was best I’ve seen in any other hotel since Covid. We enjoyed our stay."
Richard 6-night trip
Posted 3 hours ago
Talking Stick Resort

Frequently asked questions

What is West Second Street Historic District like?
Travellers will be sure to enjoy their time in Mesa's West Second Street Historic District neighbourhood.
How many hotels can I expect to find in the West Second Street Historic District area?
Book one of Expedia's 9 hotels and other accommodation options in West Second Street Historic District and start exploring everything Mesa has to offer.
If I need to cancel my hotel reservation in West Second Street Historic District, will I receive a refund?
Yes! Most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in West Second Street Historic District.
What are the top things to see and do in West Second Street Historic District?
Arizona Museum of Natural History, Mesa Amphitheatre and Arizona Museum for Youth are just a few of the places to visit in and around West Second Street Historic District. Nile Theater and Lo-fi Coffee are also worth a visit when you're out sightseeing in Mesa.