The Best Hotels in Uptown, Collinsville - 2026 Updated Prices

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Our top choices for Uptown hotels

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

1. Drury Inn & Suites St. Louis Collinsville

Eastport, 2.6 km from Uptown

Cheryl

฿3,788 total

includes taxes & fees

1 Nov - 2 Nov

A buffet area with a wooden counter, various food items, and a coffee station.

2. Comfort Inn Collinsville near St. Louis

Eastport, 2.7 km from Uptown

Chessy

฿3,865 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a central table, seating area, and a stone pillar with a mirror.

3. DoubleTree by Hilton Collinsville - St. Louis

Eastport, 2.6 km from Uptown

katie

฿4,552 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a covered entrance, stone pillars, and a parking lot.

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport, 2.9 km from Uptown

Lauren

฿3,482 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with two beds, a desk, a chair, and a TV.

5. Hampton Inn Collinsville

Eastport, 2.7 km from Uptown

Ria

฿4,057 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

6. Holiday Inn Express Troy by IHG

10 km from Uptown

Donald

฿4,402 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a large bed, a blue chair, and a wall-mounted TV.

7. Days Inn by Wyndham Collinsville/St. Louis

Eastport, 2.7 km from Uptown

Gary

฿2,333 total

includes taxes & fees

1 Nov - 2 Nov

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

8. Hampton Inn O'Fallon

10.9 km from Uptown

Edmond

฿4,284 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, two bedside lamps, a cityscape painting, a wooden headboard, and a brown chair.

9. Super 8 by Wyndham Collinsville St. Louis

Eastport, 2.8 km from Uptown

Anthony

฿2,366 total

includes taxes & fees

8 Oct - 9 Oct

A modern living room with a sofa, chairs, a coffee station, and a dining area.

10. Best Western St. Louis Fairview Heights

7.3 km from Uptown

LaShelle

฿3,035 total

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a sectional sofa, ottomans, and a round table.

11. Drury Inn & Suites St. Louis Fairview Heights

7.2 km from Uptown

Sara

฿3,418 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with a sofa, chairs, a round table, and a decorative wall with geometric patterns.

12. Holiday Inn St. Louis Fairview Heights by IHG

7.3 km from Uptown

Melvin H

฿4,330 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

13. Comfort Inn Edwardsville - St. Louis

10.9 km from Uptown

Cynthia

฿3,450 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with two beds, each with a headboard, bedside tables, lamps, and a desk with a chair.

14. Econo Lodge Inn & Suites Fairview Heights - St. Louis

7.2 km from Uptown

devon

฿2,428 total

includes taxes & fees

5 Nov - 6 Nov

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

15. Fairfield Inn & Suites by Marriott O'Fallon, IL

11.4 km from Uptown

Mohamad

฿5,356 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

16. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

11.9 km from Uptown

Rafal

฿3,917 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a fire feature, cushioned seating, and a bar area.

17. TownePlace Suites by Marriott St. Louis O'Fallon

11.1 km from Uptown

John

฿5,108 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a sofa, chairs, a fireplace, and a kitchen area in the background.

18. Country Inn & Suites by Radisson, Fairview Heights, IL

7.3 km from Uptown

Timothy

฿2,930 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a fireplace, a large painting, and multiple hanging light fixtures.

19. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

10.8 km from Uptown

Jeremy

฿4,220 total

includes taxes & fees

13 Oct - 14 Oct

A bar area with a wooden bar counter, multiple stools, and shelves stocked with bottles.

20. Radisson Hotel Fairview Heights - St. Louis

7 km from Uptown

Teresa

฿3,099 total

includes taxes & fees

18 Oct - 19 Oct

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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

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Top Uptown Hotel Reviews

Moonrise Hotel

10/10 Excellent

"I love the Moonrise and will stay here anytime I come to St. Louis. I have stayed here multiple times and never had a negative experience. Easy parking, walking to food, next door to concert venues, plus pet friendly. The rooftop bar is great too!"

21C Museum Hotel St Louis

8/10 Good

"Great location. Parking is expensive unless you can find street parking. It is a really neat old building make sure you walk around! We had a weird light that would not turn off I our room. Maintenance came and had to put tape and cardboard over it. Effective but not a long term solution for dum design"

Frequently asked questions

What is Uptown like?

Travellers to the Uptown neighbourhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Make sure that you visit Kruta Bakery and World's Largest Catsup Bottle while you're in the neighbourhood.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer in Uptown.

What is there to do in this Collinsville neighbourhood?

A few attractions you might want to check out while you're in Uptown are Kruta Bakery and World's Largest Catsup Bottle. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.

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Our top choices for Uptown hotels

1. Drury Inn & Suites St. Louis Collinsville

2. Comfort Inn Collinsville near St. Louis

3. DoubleTree by Hilton Collinsville - St. Louis

4. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

5. Hampton Inn Collinsville

6. Holiday Inn Express Troy by IHG

7. Days Inn by Wyndham Collinsville/St. Louis

8. Hampton Inn O'Fallon

9. Super 8 by Wyndham Collinsville St. Louis

10. Best Western St. Louis Fairview Heights

11. Drury Inn & Suites St. Louis Fairview Heights

12. Holiday Inn St. Louis Fairview Heights by IHG

13. Comfort Inn Edwardsville - St. Louis

14. Econo Lodge Inn & Suites Fairview Heights - St. Louis

15. Fairfield Inn & Suites by Marriott O'Fallon, IL

16. Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

17. TownePlace Suites by Marriott St. Louis O'Fallon

18. Country Inn & Suites by Radisson, Fairview Heights, IL

19. Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

20. Radisson Hotel Fairview Heights - St. Louis

Where to stay in Uptown

Eastport

Mulberry Hills

Historic Downtown Collinsville

Top Uptown Hotel Reviews

Moonrise Hotel

Frequently asked questions