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Our top choices for Syracuse luxury hotels

Exterior

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (263 reviews)
  • cleanliness
    Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
"I recently had the pleasure of staying at the Ortea Palace Luxury Hotel, and I can confidently say that it was an outstanding experience. The rooms were absolutely gorgeous, exuding a perfect blend of modern elegance and timeless charm. The attention to detail was impeccable, creating a luxurious and comfortable retreat. However, what truly made my stay exceptional was the incredibly friendly and helpful staff. Concetta, in particular, went above and beyond to assist us with activity...
United States
Jeff
The price is ฿16,562
฿18,597 total
includes taxes & fees
11 May - 12 May
Ortea Palace Hotel, Sicily, Autograph Collection
Seasonal outdoor pool, pool umbrellas, pool loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.6 out of 10, Exceptional, (77 reviews)
  • cleanliness
    Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
"Great hotel in a fantastic location. Staff very helpful.Beautiful pool with great views. "
United States
Diane
The price is ฿20,324
฿22,736 total
includes taxes & fees
13 May - 14 May
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Sports facility

Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94 reviews)
  • cleanliness
    Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness centre.
"Excellent food, amenities, excellent spa esp rosa the spa manager"
Canada
ayman
The price is ฿11,478
฿13,005 total
includes taxes & fees
18 May - 19 May
Wellness & Spa Hotel Principe di Fitalia
Exterior

Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (269 reviews)
  • cleanliness
    Syracuse seaside splendour offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
"Beautiful Resort, great sea view from all over, lovely semi private bay with sand beach"
United States
karni
The price is ฿12,342
฿14,335 total
includes taxes & fees
3 Jun - 4 Jun
Minareto
Front of property – evening/night

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (951 reviews)
  • cleanliness
    Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
"Very clean and spacious rooms."
United States
Phillip
The price is ฿11,520
฿13,052 total
includes taxes & fees
17 May - 18 May
Algila' Ortigia Charme Hotel
Bicycling

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (326 reviews)
  • cleanliness
    Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
"Our stay was perfect. We came for our honeymoon and the service, location, and customer service was impeccable. The staff anticipate your every need, super helpful and friendly, professional, and outstanding. The food at breakfast was delicious and the hotel itself feels so boutique yet polished. Will definitely tell everyone about this hotel and will stay here again! Best holiday we’ve ever been on. Grazie ancora!"
United Kingdom
Eleonora
The price is ฿11,118
฿12,609 total
includes taxes & fees
8 Jun - 9 Jun
Charme Hotel Henry's House
Front of property

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (669 reviews)
  • cleanliness
    Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
"Feeling of comfort and luxury from entering the building."
United Kingdom
Anonymous traveller
The price is ฿12,980
฿14,658 total
includes taxes & fees
31 May - 1 Jun
Palazzo Artemide - VRetreats, SLH Collection
Sauna, hot tub, Turkish bath/hammam, body treatments, body scrubs

Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (213 reviews)
  • cleanliness
    Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
"Fabulous time here! Could have stayed longer. So comfortable and the staff were so helpful. Breakfast was gorgeous. Would absolutely stay here again and recommend to a friend! "
United Kingdom
Sarah-Jane
The price is ฿10,620
฿12,062 total
includes taxes & fees
11 May - 12 May
Dimora Caiammari Luxury Hotel & Spa
Terrace/patio

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (588 reviews)
  • cleanliness
    Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
"Gorgeous historic hotel. Friendly and helpful staff. Convenient to everything. Gorgeous views for apertivo and breakfast on the rooftop."
United States
Kimberly
The price is ฿11,179
฿12,677 total
includes taxes & fees
6 Jun - 7 Jun
Grand Hotel Ortigia Siracusa
Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (274 reviews)
  • cleanliness
    Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
"Room was spacious and very clean."
United States
Junko
The price is ฿7,418
฿8,540 total
includes taxes & fees
12 May - 13 May
Caportigia Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Delightful hotel with wonderful attentive staff, beautiful food and comfortable Ed’s. Can highly recommend 🙌"
Dena 2-night trip
Posted 17 hours ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 11 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Grand Hotel Ortigia Siracusa is a luxury hotel with a private beach and spa services, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Ortea Palace Hotel, Sicily, Autograph Collection and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 11 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Teatro dei Pupi.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.