Southeast Iowa Holiday Rentals, United States of America: Private House Rentals

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Southeast Iowa

Pet friendly

Apartment

Condo

Pool

Family friendly

Hot tub

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southeast Iowa hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

A hotel room with two beds, a television, a desk with a lamp, and a chair.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Hunter

฿3,195

฿3,579 total

includes taxes & fees

11 Oct - 12 Oct

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

An indoor swimming pool with wooden walls and a balcony.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

2. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

brian

฿2,545

฿2,850 total

includes taxes & fees

8 Nov - 9 Nov

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.

A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".

A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.

3. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Sharon

฿2,817

฿3,155 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A home gym with a treadmill, elliptical, and stationary bike, a large mirror, and a framed picture on the wall.

A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

4. Best Western Mt. Pleasant Inn

Mount Pleasant

Paul

฿2,621

฿2,935 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.

A guest registration area with a counter, informational signs, and various items on shelves.

A brick building with a sign for Nauvoo Family Inn & Suites, featuring a traditional design with a tower and arched windows.

A small room with a wooden dresser, a desk, a mirror, a television, and a fan.

5. The Inn at Old Nauvoo

Nauvoo

฿4,114

฿4,648 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.

A modern hotel lobby with blue and pink seating, a central coffee table, and a kitchen area in the background.

A spa area with a hot tub, wooden ceiling, and tiled walls.

6. Quality Inn & Suites Keokuk North

Keokuk

Susan

฿3,097

฿3,469 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a chair, and a large window.

A bathroom with a bathtub, toilet, and sink.

A reception area with a white sofa, a potted plant, and a framed picture on the wall.

A small, clean room with a kitchenette, a coffee machine, a microwave, and a TV mounted on the wall. There are two tables and chairs, and a window providing natural light.

7. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

JOSE

฿2,355

฿2,637 total

includes taxes & fees

8 Nov - 9 Nov

A patio area with Adirondack chairs and a central fire pit.

A hotel room with a bed, a desk, a chair, and a TV.

A spacious dining area with multiple tables and chairs, a television on a shelf, and a large chandelier.

A snack and sundries section with shelves stocked with various products, a chalkboard with 'Snack!' written on it, and a 'Treats' sign above a display case.

8. Hampton Inn & Suites Burlington

Burlington

Susan

฿4,122

฿4,912 total

includes taxes & fees

15 Oct - 16 Oct

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

A Hampton Inn hotel with a covered entrance, a well-lit facade, and a landscaped front yard.

A reception desk with a "Welcome to the Hawk Eye State" sign, a digital kiosk, and a "Manager On Duty" sign.

9. Hampton Inn Keokuk

Keokuk

Kristopher

฿3,631

฿4,067 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside tables, a framed artwork above the bed, and two lamps on the nightstands.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a covered outdoor area.

A modern lobby with a stone wall, a reception desk, and seating areas.

A corner market with refrigerated beverage dispensers and shelves stocked with snacks.

10. Fairfield Inn & Suites by Marriott Burlington

Burlington

Matthew

฿4,261

฿4,898 total

includes taxes & fees

29 Oct - 30 Oct

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a well-lit facade.

A snack and beverage display in a store with various packaged goods and a refrigerated section.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A modern bathroom with a white sink, a mirror, and a coffee maker on a shelf.

11. Holiday Inn Express Hotel & Suites Burlington by IHG

Burlington

฿4,037

฿4,650 total

includes taxes & fees

7 Nov - 8 Nov

A room with a large window, a sofa, and a chair.

A bedroom with two beds, a ceiling fan, a TV, and a dresser.

A brick building with a balcony, a staircase, and a sign reading "Zions Mercantile".

A living room with a flat-screen TV on a white console, a grey sofa, and a framed picture on the wall.

12. Nauvoo Temple House Hotel

Nauvoo

Miranda

฿3,321

฿3,902 total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

A lobby with a reception desk, red patterned seating, a round beige ottoman, and a potted plant.

A multi-story hotel with a covered entrance and a landscaped lawn.

A hotel lobby with red seating, a checkered floor, and a large beverage dispenser.

13. Quality Inn & Suites Mount Pleasant

Mount Pleasant

Holly

฿2,201

฿2,466 total

includes taxes & fees

8 Nov - 9 Nov

A bedroom with a bed, a wooden headboard, a nightstand, a lamp, a rug, and a door.

A stone building with a wooden door, illuminated by exterior lighting.

A dining area with a round table set for four, a wooden cabinet, and a kitchen area with shelves stocked with kitchenware.

A staircase with a patterned carpet and wooden balusters.

14. Willard Richards Inn

Nauvoo

Dre

฿5,109

฿6,130 total

includes taxes & fees

31 Oct - 1 Nov

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.

A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.

15. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

฿4,844

฿5,134 total

includes taxes & fees

10 Oct - 11 Oct

A lobby with a fireplace, seating area, and an exit sign.

A hotel room with a large bathtub, a sofa, a chair, and a small table.

A modern kitchen with a microwave, coffee machine, and a juice dispenser. There is a dining area with wooden tables and chairs.

A reception area with a wooden reception desk, a red accent wall, and a kitchenette with shelves stocked with snacks.

16. Comfort Suites Burlington

Burlington

฿3,546

฿4,158 total

includes taxes & fees

1 Nov - 2 Nov

A well-lit indoor swimming pool with wooden walls and ceiling, surrounded by lounge chairs and umbrellas.

A spacious lobby with a high ceiling, wooden staircase, and a reception desk.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A hotel with a covered entrance, a parking lot, and a sign indicating it is an Embassy Suites location.

17. AmericInn by Wyndham West Burlington

West Burlington

Daniel V

฿1,859

฿2,082 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a stone accent wall, a wooden desk with a computer, a black office chair, and a brown sofa set.

A home gym with a bench press, a cable machine, and an elliptical.

A hotel room with a bed, a sofa, a desk, a chair, a TV, and a painting on the wall.

A hotel hallway with a patterned carpet, wooden doors, and a security camera on the ceiling.

18. Super 8 by Wyndham Fort Madison

Fort Madison

Debbie

฿2,259

฿2,530 total

includes taxes & fees

8 Nov - 9 Nov

A reception desk with a wooden counter, various informational pamphlets, a clock, and a window with blinds.

A coffee machine with a coffee cup and a box of tea bags on a counter.

A compact hotel bathroom with a sink, a microwave, and a small refrigerator.

19. Rivers Inn Fort Madison

Fort Madison

Dorothy

฿1,566

฿1,754 total

includes taxes & fees

30 Oct - 31 Oct

A compact kitchen with a microwave, stove, and sink. There is a cabinet with a mirror above the sink and a small shelf above the microwave. The kitchen has a tiled floor and yellow walls.

A reception desk with a wooden panel, a tiled floor, a chair, and a door.

A small bathroom with a sink, mirror, and a microwave.

A hotel room with two beds, a desk with a chair, a TV, a desk lamp, a microwave, and a painting on the wall.

20. Budget Inn

Keokuk

฿2,018

฿2,261 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

9.2/10 (162 reviews)

You can learn about the history of Nauvoo with a trip to Joseph Smith Historic Site. While you're in the area, stroll along the riverfront.

See properties

Historic Nauvoo

9.6/10 (269 reviews)

Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.

See properties

Lacey-Keosauqua State Park

8.6/10 (15 reviews)

Commune with nature and explore the great outdoors at Lacey-Keosauqua State Park during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

See properties

Snake Alley

8.6/10 (172 reviews)

Learn about the local history of Burlington when you spend time at Snake Alley. Visit the area's casinos or simply enjoy its bars.

See properties

Lake Sugema

7.0/10 (2 reviews)

Commune with nature and explore the great outdoors at Lake Sugema during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

See properties

North Lee County Historical Society

7.6/10 (17 reviews)

You can browse the exhibits at North Lee County Historical Society, a museum with a storied past, during your holiday in Fort Madison. While you're in the area, stroll along the riverfront.

See properties

Lock and Dam No. 19

8.8/10 (52 reviews)

Learn about the local history of Keokuk when you spend time at Lock and Dam No. 19. Wander the riverfront in this family-friendly area.

See properties

Spirit Hollow Golf Club

7.2/10 (29 reviews)

Enjoy a round of golf in Burlington at Spirit Hollow Golf Club. Visit the area's casinos or simply enjoy its bars.

See properties

Learn more about Southeast Iowa

Explore the family-friendly area of Southeast Iowa—a scenic riverfront, shopping and sights from Geode State Park to C.E. Richards Arena.

See all hotels in Southeast Iowa

Top Southeast Iowa Hotel Reviews

Quality Inn & Suites Keokuk North

8/10 Good

"The Staff, both check in and then Mary during breakfast was so awesome! You will be well treated there!"

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"Good stay for the price. Clean and comfortable room."

Nauvoo Vacation Villas & Condos

10/10 Excellent

"The photo listing do not do it justice. Much roomieer than the pictures show. We enjoyed the stay. I would stay here again and would recommend it to friends and family. We loved it, it was very convenient to Nauvoo and an excellent rental"

AmericInn by Wyndham West Burlington

10/10 Excellent

"Very comfortable. Price was right. Location was great for on/off highway. Finding good dining was away from lodging."

AmericInn by Wyndham Mount Pleasant

10/10 Excellent

"Great stay. Would stay again"

Hampton Inn & Suites Burlington

10/10 Excellent

"No complaints with hotel, casino on the other hand…😂"

More cheap stays in Southeast Iowa

Quality Inn & Suites Fort Madison near Hwy 61

6169 Reve Ct Fort Madison IA

฿2,817

฿3,155 total

1 Nov - 2 Nov

includes taxes & fees

Quality Inn & Suites Keokuk North

3404 Main St Keokuk IA

฿3,097

฿3,469 total

1 Nov - 2 Nov

includes taxes & fees

8.6/10 Excellent! (860 reviews)

Cobblestone Inn & Suites - Fort Madison

4901 Avenue O Fort Madison IA

฿3,195

฿3,579 total

11 Oct - 12 Oct

includes taxes & fees

Cobblestone Hotel & Suites - Ottumwa

108 Church St Ottumwa IA

฿3,330

฿3,730 total

16 Oct - 17 Oct

includes taxes & fees

9.4/10 Exceptional! (346 reviews)

Nauvoo Temple House Hotel

1200 Mulholland St Nauvoo IL

฿3,321

฿3,902 total

31 Oct - 1 Nov

includes taxes & fees

The Inn at Old Nauvoo

1875 Mulholland St Nauvoo IL

฿4,114

฿4,648 total

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (459 reviews)

Explore a world of travel with Expedia

More ways to book

Book Hotels in Southeast Iowa on Expedia.com

Find hotels in Southeast Iowa from ฿1,754

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southeast Iowa

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southeast Iowa hotels

1. Cobblestone Inn & Suites - Fort Madison

2. AmericInn by Wyndham Mount Pleasant

3. Quality Inn & Suites Fort Madison near Hwy 61

4. Best Western Mt. Pleasant Inn

5. The Inn at Old Nauvoo

6. Quality Inn & Suites Keokuk North

7. Super 8 by Wyndham Mt Pleasant

8. Hampton Inn & Suites Burlington

9. Hampton Inn Keokuk

10. Fairfield Inn & Suites by Marriott Burlington

11. Holiday Inn Express Hotel & Suites Burlington by IHG

12. Nauvoo Temple House Hotel

13. Quality Inn & Suites Mount Pleasant

14. Willard Richards Inn

15. Nauvoo Vacation Villas & Condos

16. Comfort Suites Burlington

17. AmericInn by Wyndham West Burlington

18. Super 8 by Wyndham Fort Madison

19. Rivers Inn Fort Madison

20. Budget Inn

Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

Historic Nauvoo

Lacey-Keosauqua State Park

Snake Alley

Lake Sugema

North Lee County Historical Society

Lock and Dam No. 19

Spirit Hollow Golf Club

Learn more about Southeast Iowa

Top Southeast Iowa Hotel Reviews

Quality Inn & Suites Keokuk North

Quality Inn & Suites Mount Pleasant

Nauvoo Vacation Villas & Condos

AmericInn by Wyndham West Burlington

AmericInn by Wyndham Mount Pleasant

Hampton Inn & Suites Burlington

More cheap stays in Southeast Iowa

Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Keokuk North

Cobblestone Inn & Suites - Fort Madison

Cobblestone Hotel & Suites - Ottumwa

Nauvoo Temple House Hotel

The Inn at Old Nauvoo

Explore a world of travel with Expedia

Go further with the Expedia app