A modern medical building with reflective glass windows and a clear sky.

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Tonight
6 Oct - 7 Oct
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7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
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16 Oct - 18 Oct

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Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
A modern lobby with a grey sofa, blue armchairs, and a stone accent wall.
A hotel room with two beds, a TV, a desk with a lamp, and a dresser.
A spacious indoor area with a long wooden reception desk, multiple seating arrangements, and large windows providing natural light.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
Medical Center District, 2.9 km from South Texas Medical Center
United States
Alba
฿3,020
฿3,593 total
includes taxes & fees
12 Oct - 13 Oct
Drury Inn & Suites San Antonio Northwest Medical Center
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
A reception area with a wooden reception desk, a 'Corner Market' sign, and a refrigerator stocked with beverages.
A swimming pool with a wooden ceiling, lounge chairs, and a view of trees and a building.
A modern cafe with wooden furniture, white tables, and a brick wall.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Medical Center District, 1 km from South Texas Medical Center
United States
Freddie
฿2,902
฿3,388 total
includes taxes & fees
3 Nov - 4 Nov
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
A hotel entrance with a covered walkway, a wet driveway, and a tree in the foreground.
A hotel room with a large bed, a desk, and a chair.
A courtyard with outdoor seating, a fire pit, and a covered area.

3. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
Medical Center District, 1.3 km from South Texas Medical Center
United States
Erik
฿3,292
฿3,892 total
includes taxes & fees
13 Oct - 14 Oct
Courtyard by Marriott Medical Center San Antonio
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
A gym with multiple cardio machines, including treadmills and elliptical trainers, arranged in a spacious room with a carpeted floor and neutral-colored walls.
A hotel with a red-roofed entrance, multiple floors, and a visible flag.
A hotel lobby with a reception desk, seating area, and a chandelier.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Medical Center District, 2.4 km from South Texas Medical Center
United States
Maria
฿2,980
฿3,522 total
includes taxes & fees
8 Oct - 9 Oct
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A hotel pool area with lounge chairs and a building with large windows in the background.
Exterior
A large conference room with a high ceiling, large windows, and a patterned carpet.
A large banquet hall with round tables, chairs, and chandeliers.

5. The Westin San Antonio North

The Westin San Antonio North
3.2 km from South Texas Medical Center
United States
Barbara
฿3,138
฿3,786 total
includes taxes & fees
1 Nov - 2 Nov
The Westin San Antonio North
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.
A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.
A modern bathroom with a white sink, large mirror, and towel rack.
A hotel entrance with an Atria Inn & Suites sign, a Classic Collins store, and a clear sky.

6. Atria Inn & Suites

Atria Inn & Suites
Medical Center District, 2.2 km from South Texas Medical Center
United States
Jose Rolando
฿1,938
฿2,263 total
includes taxes & fees
7 Oct - 8 Oct
Atria Inn & Suites
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.
A stone facade with a 'welcome' sign, a blue door, and a parking sign.
A compact kitchen with a built-in refrigerator, microwave, and coffee maker.
A clean, modern reception area with a large number '6' sign, a poster advertising a direct book service, and a view of the outside through a window.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
Medical Center District, 2.7 km from South Texas Medical Center
United States
Ruben
฿1,605
฿1,874 total
includes taxes & fees
18 Oct - 19 Oct
Studio 6 San Antonio, Tx - Northwest Medical Center
A modern kitchen with a large window, wooden counter, and two bar stools.
A reception desk with a modern design, featuring a white counter and dark cabinets. There are three pendant lights above the desk, and a large window with a view of greenery outside.
A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.
A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

8. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
Medical Center District, 1 km from South Texas Medical Center
United States
Joanne
฿2,243
฿2,619 total
includes taxes & fees
15 Oct - 16 Oct
Park Inn by Radisson, Medical Center
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.
A hotel with a prominent 'OYO INN & SUITES' sign, featuring a two-story structure with balconies and a covered entrance.
A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.
A hotel room with two beds, a television, a desk with a computer, and a door.

9. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
Medical Center District, 3.1 km from South Texas Medical Center
United States
Melanie
฿2,173
฿2,754 total
includes taxes & fees
19 Oct - 20 Oct
OYO Inn & Suites Medical Center San Antonio
A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.
A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.
A spacious lobby with a large refrigerator, a vending machine, and a seating area.
A small, modern room with a wooden dining table, a mirror, a TV, and a small kitchenette.

10. Motel 6 San Antonio, TX - Fiesta Trails

Motel 6 San Antonio, TX - Fiesta Trails
2.9 km from South Texas Medical Center
United States
Alexis
฿1,515
฿1,769 total
includes taxes & fees
7 Oct - 8 Oct
Motel 6 San Antonio, TX - Fiesta Trails
A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.
A hotel room with two beds, a wooden desk, and a chair.
A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.
A building with a red roof and a sign reading "Flex Studios."

11. Flex Studios

Flex Studios
Medical Center District, 2.7 km from South Texas Medical Center
United States
Jasper
฿1,477
฿1,745 total
includes taxes & fees
18 Oct - 19 Oct
Flex Studios
A motel with multiple floors, a sign indicating '6 Motel & Studio' and 'WiFi Here', and a red car parked in front.
A modern bedroom with a large bed, bedside tables, a desk, and a chair.
A building with a stone facade, a prominent '6' sign, and a parking lot with marked handicapped spaces.
A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

12. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
Medical Center District, 2.8 km from South Texas Medical Center
United States
Brian
฿1,483
฿1,899 total
includes taxes & fees
7 Oct - 8 Oct
Motel 6 San Antonio, TX - Northwest Medical Center
An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.
An outdoor patio area with multiple tables and chairs, covered by a pergola structure.
A spacious living area with a sofa, ottoman, and a large potted plant.
A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

13. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
La Cantera District, 9 km from South Texas Medical Center
United States
Eduardo
฿3,154
฿3,729 total
includes taxes & fees
26 Oct - 27 Oct
Drury Inn & Suites Near La Cantera Parkway
A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.
A modern office space with two desks, chairs, and a large window.
A large, modern hotel with multiple floors and a prominent sign reading "Embassy Suites".
A spacious living area with a large sectional sofa, multiple coffee tables, and a wooden partition.

14. Embassy Suites by Hilton San Antonio Landmark

Embassy Suites by Hilton San Antonio Landmark
La Cantera District, 8.7 km from South Texas Medical Center
United States
Lenita
฿6,197
฿7,372 total
includes taxes & fees
1 Nov - 2 Nov
Embassy Suites by Hilton San Antonio Landmark
A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.
A hotel room with a brick wall, a wooden headboard, two beds with white bedding, a bedside table with a lamp, and a wall-mounted light fixture.
A poolside area with lounge chairs and a metal railing.
A conference room with a long table, multiple chairs, and large windows offering a view of greenery and buildings.

15. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
9.2 km from South Texas Medical Center
United States
Liz
฿3,671
฿4,367 total
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express San Antonio-Airport by IHG
A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.
A modern hotel lobby with a reception desk, a coffee station, and a seating area.
A hotel entrance with a covered walkway, brick facade, and a sign indicating it is a Heritage Inn & Suites.
An outdoor patio with a pergola, pool, and outdoor seating area.

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Uptown Central, 9.5 km from South Texas Medical Center
United States
Amy
฿2,653
฿3,136 total
includes taxes & fees
5 Nov - 6 Nov
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
A modern hotel with a prominent sign reading "LA QUINTA".
A reception area with wooden reception desks, a cityscape mural, and a modern chandelier.
A modern bar area with wooden stools and a marble table, surrounded by seating with patterned cushions.
A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
9.1 km from South Texas Medical Center
United States
john
฿3,304
฿3,858 total
includes taxes & fees
19 Oct - 20 Oct
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.
A hotel entrance with a white facade, a red roof, and a logo above the name 'ESTANCIA DEL NORTE'.
A spacious bar area with a long counter, multiple stools, and a television screen.
A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
8.7 km from South Texas Medical Center
United States
Adamaris
฿4,375
฿5,172 total
includes taxes & fees
18 Oct - 19 Oct
Estancia del Norte San Antonio, Tapestry Collection by Hilton
A modern bar area with seating and a staircase leading to an upper level.
A modern building with "EMBASSY SUITES" signage, featuring a prominent entrance and landscaped surroundings.
An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.
A spacious indoor dining area with multiple tables and chairs, a high ceiling with recessed lighting, and a view of the restaurant kitchen through a glass partition.

19. Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport
Uptown Central, 9.6 km from South Texas Medical Center
United States
Arianna
฿4,128
฿4,879 total
includes taxes & fees
18 Oct - 19 Oct
Embassy Suites by Hilton San Antonio Airport
A modern kitchen with a large flat-screen TV, a glass display case with wine glasses, and a breakfast buffet sign.
A modern living room with a sofa, two armchairs, a coffee table, and a TV.
An outdoor patio area with seating, a pool, and string lights.
A modern kitchen with a large island, bar stools, and a television displaying a football game.

20. Staybridge Suites San Antonio Lackland AFB Area by IHG

Staybridge Suites San Antonio Lackland AFB Area by IHG
Far West Side, 9.8 km from South Texas Medical Center
United States
Denise
฿4,665
฿5,446 total
includes taxes & fees
25 Oct - 26 Oct
Staybridge Suites San Antonio Lackland AFB Area by IHG
View all properties

Compare popular hotels close to South Texas Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
9.2
Wonderful
1,482 reviews
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
9.0
Wonderful
1,094 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
8.8
Excellent
1,010 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
8.4
Very good
3,712 reviews
View
A hotel pool area with lounge chairs and a building with large windows in the background.
The Westin San Antonio North
8.4
Very good
1,650 reviews
View

Top South Texas Medical Center Hotel Reviews

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

10/10 Excellent
"Just loved it!"
Carlos 3-night trip
Posted 7 hours ago
Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

10/10 Excellent
"Staff kind, nice, professional and very willing to help you. Kitchen very slow, do not eat there"
Gonzalo 1-night trip
Posted 16 hours ago
Courtyard by Marriott Medical Center San Antonio
The Westin San Antonio North

The Westin San Antonio North

8/10 Good
"The hotel was fine for what I needed - somewhere decent to stay for one night. It was not the level of quality or amenities that I would normally expect from a Westin - mostly just very dated. Area and parking lot seemed safe, which was nice."
Dustin 1-night trip
Posted 20 hours ago
The Westin San Antonio North
Atria Inn & Suites

Atria Inn & Suites

10/10 Excellent
"It’s. Nice place to stay, it’s big and comfortable."
Jose Rolando 1-night trip
Posted 2 days ago
Atria Inn & Suites
Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

10/10 Excellent
"Clean room"
Cordale 1-night trip
Posted 7 days ago
Motel 6 San Antonio, TX - Northwest Medical Center
Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center

10/10 Excellent
"🙌"
Alex 1-night trip
Posted 7 days ago
Sonesta ES Suites San Antonio Northwest - Medical Center
Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center

10/10 Excellent
"Rooms were clean"
Alycia 2-night trip
Posted 10 days ago
Park Inn by Radisson, Medical Center
Flex Studios

Flex Studios

10/10 Excellent
"Its not to bad a place. Very affordable and reasonable. I Have stayed at way worse. I plan on staying about two months. I been there two weeks."
Carlos 1-night trip
Posted 1 month ago
Flex Studios

Frequently asked questions

What's the area like around South Texas Medical Center?
South Texas Medical Center is located in a walkable area of San Antonio known for its stunning river views and cycling. If you're looking for a convenient place to stay, take a look at the 35 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to South Texas Medical Center?
Fairfield Inn & Suites by Marriott San Antonio Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.6 mi (1 km) from South Texas Medical Center. Other good options close by include Courtyard by Marriott Medical Center San Antonio and Park Inn by Radisson, Medical Center.
How many hotels should I expect to find close to South Texas Medical Center?
Expedia has 35 hotels and other accommodation options within a mile from South Texas Medical Center.
If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near South Texas Medical Center.
What can I see and do near South Texas Medical Center?
You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre and Laugh Out Loud Comedy Club if you're interested in local theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.