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Find hotels in South San Diego, CA from ฿1,952

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Our top choices for South San Diego hotels

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
Imperial Beach
9.4 out of 10, Exceptional, (961)
"Great stay"
United States
Crystal
The price is ฿3,882
฿4,426 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Imperial Beach San Diego

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1573)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is ฿3,693
฿4,201 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

BORDER PLAZA HOTEL

BORDER PLAZA HOTEL
2.0 star property
San Ysidro
7.4 out of 10, Good, (62)
"Clean and friendly "
United States
Myndee
The price is ฿2,390
฿2,718 total
includes taxes & fees
29 Dec - 30 Dec
BORDER PLAZA HOTEL

Pier South Resort, Autograph Collection by Marriott

Pier South Resort, Autograph Collection by Marriott
4.0 star property
Imperial Beach
8.4 out of 10, Very good, (1002)
"Room was beautiful, everything about my stay was perfect."
United States
Victoria
The price is ฿4,986
฿6,391 total
includes taxes & fees
4 Jan - 5 Jan 2026
Pier South Resort, Autograph Collection by Marriott

Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1336)
"Nice breakfast "
United States
Marcos
The price is ฿2,610
฿2,876 total
includes taxes & fees
30 Dec - 31 Dec
Hercor Hotel - Urban Boutique

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
San Ysidro
9.0 out of 10, Wonderful, (1203)
"Staff was very courteous and room was well cleaned"
United States
Francisco
The price is ฿3,403
฿3,871 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Americana Inn

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1500)
"Everything was great, staff , Room , clean , great place to stay "
United States
Luis
The price is ฿2,849
฿3,134 total
includes taxes & fees
25 Jan - 26 Jan 2026
La Quinta Inn by Wyndham San Diego Chula Vista

ERTH INN by AGA- San Ysidro

ERTH INN by AGA- San Ysidro
2.5 star property
San Ysidro
7.8 out of 10, Good, (44)
"Very relaxing stay, quiet, and clean"
United States
Victor
The price is ฿2,207
฿2,466 total
includes taxes & fees
29 Dec - 30 Dec
ERTH INN by AGA- San Ysidro

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
Chula Vista
8.2 out of 10, Very good, (1266)
"Great hotel"
United States
Rafael
The price is ฿3,007
฿3,314 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn Chula Vista San Diego South

The Rambler

The Rambler
3.0 star property
Chula Vista
9.2 out of 10, Wonderful, (2012)
"Absolutely amazing stay will def be coming back!"
United States
Victor
The price is ฿3,290
฿3,806 total
includes taxes & fees
29 Dec - 30 Dec
The Rambler

Quality Inn San Diego South - Chula Vista

Quality Inn San Diego South - Chula Vista
2.5 star property
Chula Vista
7.8 out of 10, Good, (1002)
"Good food for breakfast "
United States
Aaron
The price is ฿2,084
฿2,292 total
includes taxes & fees
7 Jan - 8 Jan 2026
Quality Inn San Diego South - Chula Vista

Motel 6 San Ysidro, CA - San Diego - Border

Motel 6 San Ysidro, CA - San Diego - Border
2.0 star property
San Ysidro
7.0 out of 10, Good, (1476)
"exceptional "
United States
Clarissa
The price is ฿2,181
฿2,481 total
includes taxes & fees
4 Jan - 5 Jan 2026
Motel 6 San Ysidro, CA - San Diego - Border

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
Chula Vista
9.2 out of 10, Wonderful, (1016)
"Clean room, great staff, and good breakfast"
United States
Jean
The price is ฿3,482
฿3,830 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express San Diego South - Chula Vista by IHG

El Primero Hotel

El Primero Hotel
2.5 star property
Downtown Chula Vista
9.2 out of 10, Wonderful, (1001)
"The owner was very hospitable. My room was so clean and tidy."
United States
Jiabao
The price is ฿2,626
฿2,888 total
includes taxes & fees
29 Dec - 30 Dec
El Primero Hotel

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
Otay Ranch
9.8 out of 10, Exceptional, (1117)
"Cozy room, ver nice staff and in a great location to restaurants and shopping. "
United States
Amanda
The price is ฿5,462
฿6,019 total
includes taxes & fees
2 Jan - 3 Jan 2026
Ayres Hotel San Diego South - Chula Vista

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
Otay
7.8 out of 10, Good, (1555)
"The breakfast was good there were healthy options. "
United States
Selene
The price is ฿3,139
฿3,453 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Chula Vista/Otay Valley Hotel

Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
Chula Vista
7.2 out of 10, Good, (2011)
"Great stay"
United States
Eleazar
The price is ฿1,918
฿2,109 total
includes taxes & fees
30 Dec - 31 Dec
Hotel Palmeras Chula Vista

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1002)
"Beautiful place "
United States
Joe
The price is ฿3,248
฿3,694 total
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Suites San Diego Otay Mesa

SureStay Hotel by Best Western Chula Vista San Diego Bay

SureStay Hotel by Best Western Chula Vista San Diego Bay
3.0 star property
Chula Vista
8.0 out of 10, Very good, (1554)
"Great stay, "
United States
chizomanze
The price is ฿2,486
฿2,740 total
includes taxes & fees
4 Jan - 5 Jan 2026
SureStay Hotel by Best Western Chula Vista San Diego Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
San Ysidro
7.8 out of 10, Good, (1426)
"The staff was nice "
United States
Claudia
The price is ฿2,172
฿2,475 total
includes taxes & fees
29 Dec - 30 Dec
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about South San Diego

Explore the family-friendly area of South San Diego—live music, theatres and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

Captured this guy doing a wheelie during a beautiful sunset! #imperialbeach #EndlessSummer #autographhotels #Marriott #piersouthresort
Photo by Karen Leone
Open Photo by Karen Leone

Top South San Diego Hotel Reviews

More cheap stays in South San Diego