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Check prices for these dates

Tonight
15 Feb - 16 Feb
Tomorrow
16 Feb - 17 Feb
Next weekend
20 Feb - 22 Feb
In two weeks
27 Feb - 1 Mar

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Our top choices for Sioux Empire Medical Museum hotels

Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.8 out of 10, Exceptional, (11 reviews)
"We were the first people to stay in this room. Great front desk people. Will absolutely stay here again."
United States
Caden
The price is ฿4,195
฿4,664 total
includes taxes & fees
11 Mar - 12 Mar
Highpoint Hotel
Terrace/patio

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (604 reviews)
"Clean room | Breakfast Great | Wonderful and Helpful Staff"
United States
Natalie
The price is ฿3,287
฿3,668 total
includes taxes & fees
22 Feb - 23 Feb
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Interior detail

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,355 reviews)
"Nice place to stay"
United States
Andy
Hotel On Phillips
Exterior detail

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,019 reviews)
"The stay was fantastic!"
United States
Cleo
The price is ฿4,142
฿4,970 total
includes taxes & fees
16 Feb - 17 Feb
Clubhouse Hotel Suites Sioux Falls
Meeting facility

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (180 reviews)
"Amazing place to stay! "
United States
Marius
The price is ฿4,357
฿4,966 total
includes taxes & fees
23 Feb - 24 Feb
Canopy By Hilton Sioux Falls Downtown
Exterior

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay "
United States
Troy
The price is ฿3,287
฿3,668 total
includes taxes & fees
22 Feb - 23 Feb
Hampton Inn Sioux Falls
Meeting facility

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (899 reviews)
"Nice hotel! "
United States
Sara
The price is ฿3,542
฿4,072 total
includes taxes & fees
22 Feb - 23 Feb
Hilton Garden Inn Sioux Falls Downtown
Porch

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.5 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (56 reviews)
"It was a great place to stay and super interesting."
United States
Kathy
The price is ฿4,195
฿5,112 total
includes taxes & fees
16 Feb - 17 Feb
Historic Victorian Inn
Exterior

Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,189 reviews)
"Staff was awesome and the room was nice and clean beds were comfortable. The breakfast was great."
United States
Debra
The price is ฿2,744
฿3,072 total
includes taxes & fees
22 Feb - 23 Feb
Country Inn & Suites by Radisson, Sioux Falls
Exterior

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,004 reviews)
"Nice place to stay good restaurants and bars within the facility courteous service and good quality food also. "
United States
Paul
The price is ฿2,704
฿3,028 total
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Sioux Falls-City Centre by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (1,000 reviews)
"The breakfast was amazing and plenty of options with cold food and hot. The staff were great too and so was our room. "
United States
JACKIE
The price is ฿3,884
฿4,323 total
includes taxes & fees
24 Feb - 25 Feb
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Lobby

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,003 reviews)
"Clean and friendly "
United States
Eddie
The price is ฿3,011
฿3,365 total
includes taxes & fees
22 Feb - 23 Feb
Sheraton Sioux Falls Hotel & Convention Center
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (723 reviews)
"Friendly front staff"
United States
Susan
The Center Inn
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,000 reviews)
"Clean room Friendliness Great location for us "
United States
Rhonda or doug
Valley Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,512 reviews)
"Clean rooms, nice pool area, nice staff!!"
United States
Kristian
The price is ฿1,996
฿2,252 total
includes taxes & fees
22 Feb - 23 Feb
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
50-inch flat-screen TV with cable channels, fireplace, Netflix

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.4 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (3 reviews)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
The price is ฿8,362
฿9,483 total
includes taxes & fees
16 Feb - 17 Feb
Historic Twin Tudors Inn
Exterior

WoodSpring Suites Sioux Falls

WoodSpring Suites Sioux Falls
2.5 star property
2.8 km from Sioux Empire Medical Museum
5.4 out of 10, (61 reviews)
"Clean room, Friendly staff"
United States
Satoya
The price is ฿1,833
฿2,073 total
includes taxes & fees
16 Feb - 17 Feb
WoodSpring Suites Sioux Falls
Lobby

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.6 out of 10, (1,000 reviews)
"Good room for the price."
United States
Michael
The price is ฿1,638
฿1,859 total
includes taxes & fees
22 Feb - 23 Feb
Ramada by Wyndham Sioux Falls
Terrace/patio

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.8 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,000 reviews)
"This is such a great hotel. It's clean, nicely decorated, and the staff are so friendly. The breakfast is delicious, and it would be a great place to enjoy in the summer for the patio that overlooks a pond."
United States
Rachel
The price is ฿3,636
฿4,051 total
includes taxes & fees
1 Mar - 2 Mar
Hyatt Place Sioux Falls South
Breakfast, lunch and dinner served

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 3.4 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (857 reviews)
"Clean Room. Beautiful pool and hot tub area. Great location. "
United States
Carissa
The price is ฿3,325
฿3,710 total
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn & Suites Sioux Falls - Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Sioux Empire Medical Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains
Highpoint Hotel
3.0 star property
9.8
Exceptional
11 reviews
View
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4
Exceptional
604 reviews
View
Interior detail
Hotel On Phillips
2.5 star property
9.6
Exceptional
1,355 reviews
View
Exterior detail
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6
Exceptional
1,019 reviews
View
Meeting facility
Canopy By Hilton Sioux Falls Downtown
4.0 star property
9.4
Exceptional
180 reviews
View

Top Sioux Empire Medical Museum Hotel Reviews

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown

10/10 Excellent
"Room spotless. Staff professional and courteous. "
Teresa 1-night trip
Posted 3 days ago
Canopy By Hilton Sioux Falls Downtown

Hotels near other Sioux Empire Medical Museum attractions

Great Plains Zoo

4.3/5 (74 reviews)
Why not meet the animals who live at Great Plains Zoo during your holiday in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 127 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Valley Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free parking and free WiFi. Another good choice is Highpoint Hotel, located just 0.1 mi (0.2 km) away.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 127 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Old Courthouse Museum and Center for Western Studies feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Falls Park, Sherman Park or Fawick Park if you want a dose of fresh air.