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Check prices for these dates

This weekend
22 May - 24 May
Next weekend
29 May - 31 May

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Our top choices for Sioux Empire Medical Museum hotels

Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.8 out of 10, Exceptional, (91 reviews)
"We had a great stay"
United States
jaime
The price is ฿4,953
฿5,498 total
includes taxes & fees
4 Jun - 5 Jun
Highpoint Hotel
Terrace/patio

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (643 reviews)
"Hotel was and room were nice, clean, spacious"
United States
Michael
The price is ฿4,208
฿4,681 total
includes taxes & fees
24 May - 25 May
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Interior detail

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,418 reviews)
"Our favorite SF stay, every time"
United States
Danielle
The price is ฿5,685
฿6,302 total
includes taxes & fees
7 Jun - 8 Jun
Hotel On Phillips
Exterior detail

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,064 reviews)
"Wonderful place to stay with my family, great amenities on site!"
United States
Chelsey
The price is ฿4,367
฿5,238 total
includes taxes & fees
24 May - 25 May
Clubhouse Hotel Suites Sioux Falls
Meeting facility

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (215 reviews)
"Excellent hotel will stay there again"
United States
Ryan
The price is ฿5,362
฿6,078 total
includes taxes & fees
24 May - 25 May
Canopy By Hilton Sioux Falls Downtown
Exterior

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,015 reviews)
"we usually stay here we like the location, breakfast, staff, parking, etc"
United States
janice
The price is ฿3,948
฿4,397 total
includes taxes & fees
26 May - 27 May
Hampton Inn Sioux Falls
Meeting facility

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (932 reviews)
"Great stay!"
United States
Marius
The price is ฿3,711
฿4,267 total
includes taxes & fees
7 Jun - 8 Jun
Hilton Garden Inn Sioux Falls Downtown
Porch

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.5 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (59 reviews)
"Property is very beautifully restored. The room was comfortable and cozy. The owner was very friendly and helpful. We will definately book again"
United States
Kathy
The price is ฿3,780
฿4,681 total
includes taxes & fees
16 Jun - 17 Jun
Historic Victorian Inn
Exterior

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean rooms, friendly staff, good breakfast"
United States
Steve
The price is ฿4,070
฿4,530 total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Exterior

Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,232 reviews)
"Nice hotel great location"
United States
Mark
The price is ฿3,526
฿3,933 total
includes taxes & fees
25 May - 26 May
Country Inn & Suites by Radisson, Sioux Falls
Exterior

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,000 reviews)
"Great stay in March!"
Canada
Matthew
The price is ฿4,070
฿5,019 total
includes taxes & fees
31 May - 1 Jun
Holiday Inn Sioux Falls-City Centre by IHG
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (776 reviews)
"Very nice affordable place right next to the Avera Hospital."
United States
Colette
The price is ฿3,104
฿3,471 total
includes taxes & fees
22 May - 23 May
The Center Inn
Lobby

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay"
United States
Justin
The price is ฿3,432
฿3,830 total
includes taxes & fees
7 Jun - 8 Jun
Sheraton Sioux Falls Hotel & Convention Center
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,001 reviews)
"Others a great stay and a location for the reason for my travel."
United States
Mike
The price is ฿3,194
฿3,569 total
includes taxes & fees
22 May - 23 May
Valley Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,564 reviews)
"The rooms were clean and stay was great. "
Canada
John
The price is ฿2,403
฿2,701 total
includes taxes & fees
25 May - 26 May
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Exterior

WoodSpring Suites Sioux Falls

WoodSpring Suites Sioux Falls
2.5 star property
2.8 km from Sioux Empire Medical Museum
5.4 out of 10, (75 reviews)
"Yes woodsprings is a nice living area.Its clean,staff is friendly.Its in a great location.Thank you Woodsprings for all you do..."
United States
Arie
The price is ฿2,247
฿2,530 total
includes taxes & fees
24 May - 25 May
WoodSpring Suites Sioux Falls
Lobby

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.6 out of 10, (1,000 reviews)
"AC is super quiet and effective. Staff are super helpful and friendly."
United States
Randall C.
The price is ฿2,279
฿2,566 total
includes taxes & fees
24 May - 25 May
Ramada by Wyndham Sioux Falls
Terrace/patio

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.8 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,001 reviews)
"Was very clean, breakfast was great, property was beautiful! "
United States
Chris
The price is ฿4,461
฿4,959 total
includes taxes & fees
16 Jun - 17 Jun
Hyatt Place Sioux Falls South
Exterior

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 3.4 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (881 reviews)
"Nice rooms and great staff "
United States
Darcy
The price is ฿4,135
฿4,602 total
includes taxes & fees
31 May - 1 Jun
Holiday Inn & Suites Sioux Falls - Airport by IHG
Property amenity

Staybridge Suites Sioux Falls by IHG

Staybridge Suites Sioux Falls by IHG
3.0 star property
Mall District, 3.2 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,001 reviews)
"Great breakfast great pool area great place!"
United States
Jacob
The price is ฿3,171
฿3,544 total
includes taxes & fees
25 May - 26 May
Staybridge Suites Sioux Falls by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Sioux Empire Medical Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains
Highpoint Hotel
3.0 star property
9.8
Exceptional
91 reviews
View
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4
Exceptional
643 reviews
View
Interior detail
Hotel On Phillips
2.5 star property
9.6
Exceptional
1,418 reviews
View
Exterior detail
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6
Exceptional
1,064 reviews
View
Meeting facility
Canopy By Hilton Sioux Falls Downtown
4.0 star property
9.4
Exceptional
215 reviews
View

Top Sioux Empire Medical Museum Hotel Reviews

Highpoint Hotel

Highpoint Hotel

8/10 Good
"ok"
John 1-night trip
Posted 1 hour ago
Highpoint Hotel

Hotels near other Sioux Empire Medical Museum attractions

Great Plains Zoo

4.3/5 (136 reviews)
Why not meet the animals who live at Great Plains Zoo during your holiday in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 129 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Highpoint Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices close by include Valley Inn and Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 129 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Old Courthouse Museum and Center for Western Studies feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Falls Park, Sherman Park or Fawick Park if you want a dose of fresh air.