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Check availability on Seneca Family-Friendly Hotels

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Seneca family-friendly hotels

Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is ฿3,569
฿3,926 total
includes taxes & fees
31 Dec - 1 Jan 2026
Fairfield Inn & Suites Seneca Clemson Univ Area
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (52)
"Excellent stay."
United States
Beonca
The price is ฿2,762
฿4,404 total
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very good, (1001)
"Clean room, staff nice"
United States
Selena
The price is ฿2,351
฿2,609 total
includes taxes & fees
29 Dec - 30 Dec
Microtel Inn & Suites by Wyndham Anderson/Clemson
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (785)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is ฿4,624
฿5,133 total
includes taxes & fees
20 Jan - 21 Jan 2026
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

10/10 Excellent
"Property, room, and front desk were all very nice. Safety strips in the bathtub would be my only suggestion. "
Norma 1-night trip
Posted 1 month ago
Quality Inn Seneca Clemson Area US-123

Frequently asked questions

What's Seneca like for family-friendly holidays?
The welcoming destination of Seneca is a good choice if you've been considering a getaway with your children. The boating, lake views and sporting events are just some of the things that make this the perfect spot for family trips. Fly into Greenville, SC (GSP-Greenville-Spartanburg Intl.), which is located 44.1 mi (71 km) from the city centre.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly holiday in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.
What's there to see and do with your family in Seneca?
While you and your family are holidaying in Seneca, you may want to visit some family-friendly attractions such as Oconee County Library Seneca Branch and The Gauntlet. Make sure that you have lots of time for activities such as Bertha Lee Strickland Cultural Museum and Golden Corner Plaza.