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Check prices for these dates

In two weeks
16 Jan - 18 Jan
In two months
27 Feb - 1 Mar
In three months
27 Mar - 29 Mar
In four months
24 Apr - 26 Apr

Our top choices for Santee holiday rentals

Beach nearby
Coronado Beach Resort

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (754)
"Room was clean, Staff pleasant. "
United States
Vicki
The price is ฿6,182
฿6,800 total
includes taxes & fees
5 Jan - 6 Jan 2026
Coronado Beach Resort
Premium bedding, pillow-top beds, desk, laptop workspace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (614)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is ฿3,449
฿4,911 total
includes taxes & fees
3 Jan - 4 Jan 2026
Sentral Gaslamp Quarter
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace
Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
8.0 out of 10, Very good, (154)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
Kasa Gaslamp Quarter San Diego
Outdoor pool, a heated pool
Wave Crest Resort

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (144)
"Great location "
United States
Erin
The price is ฿6,449
฿8,354 total
includes taxes & fees
6 Jan - 7 Jan 2026
Wave Crest Resort
Suite, 2 Bedrooms, Non Smoking | Private kitchen | Full-sized fridge, microwave, oven, stovetop
San Diego Country Estates

San Diego Country Estates

San Diego Country Estates
2.5 star property
San Diego Country Estates
9.4 out of 10, Exceptional, (246)
"The staff was amazing, the suite super clean and quiet place to relax"
United States
Javier
The price is ฿3,057
฿4,151 total
includes taxes & fees
8 Jan - 9 Jan 2026
San Diego Country Estates
Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Lobby sitting area
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (265)
"Overall good place."
United States
Isaac
The price is ฿3,228
฿3,639 total
includes taxes & fees
4 Jan - 5 Jan 2026
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Outdoor pool
Kasa Little Italy San Diego

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (357)
"Clean room, Kitchen was fully equipped. Had a great stay!"
United States
Miranda
The price is ฿6,260
฿9,893 total
includes taxes & fees
4 Jan - 5 Jan 2026
Kasa Little Italy San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

10/10 Excellent
"I absolutely love the special touches this hotel – especially in the lobby. It smells really good clean. It’s very welcoming and they have a beautiful Christmas tree for those of us traveling and not being able to be home for the holidays. The rooms are very clean modern and the beds are super comfortable. Definitely a great find!"
Karla 1-night trip
Posted 2 days ago
Best Western Plus Marina Gateway Hotel

Find out more about Santee

Search for holiday rentals in Santee on Expedia! You can easily find your home rentals, villas, holiday apartments in Santee using one of the methods below:

  • View our selection of featured holiday rentals in Santee
  • Use the map to find apartments and other holiday homes in the Santee neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santee while they last

Look no further and take a look at our great range of rental properties in Santee!

Frequently asked questions

Can I find a holiday rental in Santee?

Yes, we offer holiday rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a secluded option if you want a quiet place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

How many holiday rentals are there in Santee?

Expedia has 6 holiday rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Mission Trails Regional Park and Sportsplex USA Santee are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Petco Park are other popular places to visit in the area.

What are holiday rentals like in Santee?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santee. Holiday rentals offer extras such as kitchens and laundry facilities so your stay will be comfortable. If you're concerned about a clean environment, a holiday rental can provide a sense of seclusion away from shared hotel lifts and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular choice for a family trip or a small group gathering.