A tropical island with a beach, clear turquoise waters, and lush greenery.

Find hotels in Santa Isabel from ฿9,912

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Isabel hotels

Reserve now, pay later
Exterior

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
The price is ฿68,492
฿75,341 total
includes taxes & fees
1 Aug - 2 Aug
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Property grounds

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
The price is ฿9,011
฿9,912 total
includes taxes & fees
2 Aug - 3 Aug
Cabins on paradise San Blas island
Exterior

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
The price is ฿11,894
฿13,083 total
includes taxes & fees
4 Aug - 5 Aug
Cabañas Nalunega San Blas
View from property

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
The price is ฿12,896
฿14,186 total
includes taxes & fees
4 Aug - 5 Aug
Cabañas Isla Nubesidub San Blas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkelling. Hike through lush rainforest trails to spot colourful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

See all hotels in Santa Isabel
A tropical island with a beach, clear turquoise waters, and lush greenery.

Top Santa Isabel Hotel Reviews

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 5 months ago
Private Ocean-Front Cabin with private bathroom on San Blas Island

More cheap stays in Santa Isabel

Cabins on paradise San Blas island

Cabins on paradise San Blas island

9.587566, -78.879820 Narganá San Blas
The price is ฿9,011 per night from 2 Aug to 3 Aug
฿9,011
฿9,912 total
2 Aug - 3 Aug
includes taxes & fees

Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 17 mi (27.3 km) from the heart of Santa Isabel, Cocoloco - Catamaran Lagoon 52F SAN BLAS is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Private Ocean-Front Cabin with private bathroom on San Blas Island and Private wood Cabins on San Blas island - private bathroom. See all available top hotels, or vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer, including its parks. There are 39 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Museum, Chagres National Park and Porvenir Museum. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the weather like in Santa Isabel?
The hottest months are usually June and September, with an average temperature of 27°C, while the coldest months are February and March, with an average of 26°C. The rainiest months in Santa Isabel are October, August, July and November, with each month seeing an average of 310 mm of rainfall.