Search Hotels Near Santa Fe Medical Center, Las Vegas

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Our top choices for Santa Fe Medical Center hotels

Lounge
Hotel Jefe at Ojos Locos

Hotel Jefe at Ojos Locos

Hotel Jefe at Ojos Locos
3.0 star property
2.7 km from Santa Fe Medical Center
7.8 out of 10, Good, (2247)
"Very good food and drinks at the bar"
United States
Kenneth
The price is ฿1,946
฿2,199 total
includes taxes & fees
29 Dec - 30 Dec
Hotel Jefe at Ojos Locos
Basic Double Room, 1 Queen Bed, Balcony, City View | Balcony
The Yellow Penthouse

The Yellow Penthouse

The Yellow Penthouse
2.5 star property
1.9 km from Santa Fe Medical Center
6.2 out of 10, (161)
"Not bad for that price "
United States
Habibullah
The Yellow Penthouse
Deluxe Suite (1 King Bed Non Smoking) | View from room
Sunrise Inn Hotel

Sunrise Inn Hotel

Sunrise Inn Hotel
2.5 star property
3 km from Santa Fe Medical Center
5.8 out of 10, (1000)
"Good price and comfortable beds"
United States
pierre
Sunrise Inn Hotel
Front of property
Studio 6 North Las Vegas, NV

Studio 6 North Las Vegas, NV

Studio 6 North Las Vegas, NV
2.5 star property
1.2 km from Santa Fe Medical Center
5.4 out of 10, (642)
"Nice and quiet but walkable to everywhere perfect location "
United States
Christine
The price is ฿2,242
฿2,533 total
includes taxes & fees
29 Dec - 30 Dec
Studio 6 North Las Vegas, NV
Exterior
Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
4.3 km from Santa Fe Medical Center
9.4 out of 10, Exceptional, (5395)
"We enjoyed our stay"
United States
Grecia
The price is ฿3,693
฿5,927 total
includes taxes & fees
29 Dec - 30 Dec
Circa Resort & Casino – Adults Only
Outdoor pool
Homewood Suites By Hilton North Las Vegas Speedway

Homewood Suites By Hilton North Las Vegas Speedway

Homewood Suites By Hilton North Las Vegas Speedway
2.0 star property
5.2 km from Santa Fe Medical Center
9.6 out of 10, Exceptional, (118)
"Nice stay"
United States
Prakash
The price is ฿4,046
฿4,572 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites By Hilton North Las Vegas Speedway
Outdoor pool
Element LAS Vegas Symphony Park

Element LAS Vegas Symphony Park

Element LAS Vegas Symphony Park
3.0 star property
5 km from Santa Fe Medical Center
9.4 out of 10, Exceptional, (29)
"The room was spacious and the staff was friendly. "
United States
Kimberly
The price is ฿5,245
฿6,703 total
includes taxes & fees
29 Dec - 30 Dec
Element LAS Vegas Symphony Park
Terrace/patio
Home2 Suites By Hilton Las Vegas North

Home2 Suites By Hilton Las Vegas North

Home2 Suites By Hilton Las Vegas North
3.0 star property
5.6 km from Santa Fe Medical Center
9.4 out of 10, Exceptional, (193)
"Very nice place to stay and the staff were great. "
United States
Steven
The price is ฿4,035
฿4,559 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites By Hilton Las Vegas North
Exterior
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
5.5 km from Santa Fe Medical Center
9.4 out of 10, Exceptional, (98)
"Amazing "
United States
Haned
The price is ฿5,555
฿6,277 total
includes taxes & fees
11 Jan - 12 Jan 2026
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
Seasonal outdoor pool
SpringHill Suites Las Vegas North Speedway

SpringHill Suites Las Vegas North Speedway

SpringHill Suites Las Vegas North Speedway
3.0 star property
4.9 km from Santa Fe Medical Center
9.2 out of 10, Wonderful, (646)
"Nice place"
United States
John
The price is ฿4,717
฿5,331 total
includes taxes & fees
25 Jan - 26 Jan 2026
SpringHill Suites Las Vegas North Speedway
Buffet
Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
4 km from Santa Fe Medical Center
8.8 out of 10, Excellent, (2811)
"Great location and price."
United States
Rhonda
The price is ฿934
฿2,213 total
includes taxes & fees
4 Jan - 5 Jan 2026
Main Street Station Hotel, Casino and Brewery
Property amenity
TownePlace Suites by Marriott Las Vegas North I-15

TownePlace Suites by Marriott Las Vegas North I-15

TownePlace Suites by Marriott Las Vegas North I-15
3.0 star property
7.8 km from Santa Fe Medical Center
9.8 out of 10, Exceptional, (499)
"This is second time staying in same hotel. Happy with location and stay."
United States
Siva
The price is ฿4,469
฿5,050 total
includes taxes & fees
30 Dec - 31 Dec
TownePlace Suites by Marriott Las Vegas North I-15
Exterior
Hampton Inn Las Vegas North Speedway

Hampton Inn Las Vegas North Speedway

Hampton Inn Las Vegas North Speedway
2.5 star property
4.9 km from Santa Fe Medical Center
8.8 out of 10, Excellent, (876)
"The staff was very friendly, great amenities and property was clean and well kept. "
United States
David
The price is ฿3,792
฿4,285 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn Las Vegas North Speedway
Exterior
La Quinta Inn & Suites by Wyndham Las Vegas Nellis

La Quinta Inn & Suites by Wyndham Las Vegas Nellis

La Quinta Inn & Suites by Wyndham Las Vegas Nellis
3.0 star property
6.3 km from Santa Fe Medical Center
9.2 out of 10, Wonderful, (1000)
"Even though the property was under construction, the staff, room and breakfast was awesome. Definitely recommend this place "
United States
Elsa
The price is ฿3,855
฿4,356 total
includes taxes & fees
29 Dec - 30 Dec
La Quinta Inn & Suites by Wyndham Las Vegas Nellis
Luxury Penthouse | Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Ahern Hotel Las Vegas

Ahern Hotel Las Vegas

Ahern Hotel Las Vegas
3.5 star property
7.4 km from Santa Fe Medical Center
9.4 out of 10, Exceptional, (11229)
"Great stay"
United States
Malikah
The price is ฿2,588
฿2,934 total
includes taxes & fees
11 Jan - 12 Jan 2026
Ahern Hotel Las Vegas
Premium bedding, pillow-top beds, desk, laptop workspace
My Place Hotel - North Las Vegas

My Place Hotel - North Las Vegas

My Place Hotel - North Las Vegas
2.5 star property
5.1 km from Santa Fe Medical Center
8.8 out of 10, Excellent, (1001)
"All was good with check in, room in great condition, location is what I wanted. "
United States
James
The price is ฿3,383
฿3,823 total
includes taxes & fees
11 Jan - 12 Jan 2026
My Place Hotel - North Las Vegas
Bar (on property)
Downtown Grand Las Vegas

Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
4.1 km from Santa Fe Medical Center
8.4 out of 10, Very good, (9939)
"Great place !"
United States
Annaelizabeth
The price is ฿1,210
฿2,735 total
includes taxes & fees
12 Jan - 13 Jan 2026
Downtown Grand Las Vegas
In-room safe, blackout curtains, iron/ironing board, free WiFi
El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
4.1 km from Santa Fe Medical Center
8.4 out of 10, Very good, (7097)
"Easy checkin and great staff"
United States
Cesar
El Cortez Hotel and Casino - 21 and Over
Lobby
Four Queens Hotel and Casino

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
4.3 km from Santa Fe Medical Center
8.4 out of 10, Very good, (6695)
"Would stay again"
United States
Mackena Ryann
The price is ฿1,740
฿1,966 total
includes taxes & fees
11 Jan - 12 Jan 2026
Four Queens Hotel and Casino
Pet-friendly
Desert Moon Motel

Desert Moon Motel

Desert Moon Motel
2.5 star property
4 km from Santa Fe Medical Center
8.4 out of 10, Very good, (401)
"I have to admit I was nervous when I arrived to the motel because the area around the motel was run down with closed and empty buildings but I was pleasantly surprised when I got my room it was newly updated and very clean. The staff was very friendly. I would stay again on my next trip to Vegas. "
United States
cynthia
Desert Moon Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Medical Center Hotel Reviews

Four Queens Hotel and Casino

Four Queens Hotel and Casino

10/10 Excellent
"The room was great!"
Linda 2-night trip
Posted 9 hours ago
Four Queens Hotel and Casino

Hotels near other Santa Fe Medical Center attractions

Planetarium Observatory

4.7/5 (43 reviews)
Enjoy a stop at Planetarium Observatory, an entertaining place to visit in North Las Vegas. Visit the casinos and lively bars in this family-friendly area.
See properties

Bighorn Casino

4.6/5 (32 reviews)
Why not roll the dice with a visit to Bighorn Casino during your time in North Las Vegas? Visit the casinos and shops in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Santa Fe Medical Center?
Santa Fe Medical Center is located in North Las Vegas. This family-friendly area is known for its first-class casinos and renowned opera house. If you're looking for a convenient place to stay, take a look at the 17 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Santa Fe Medical Center?
Located a short 0.8 mi (1.2 km) from Santa Fe Medical Center, Studio 6 North Las Vegas, NV is one of the top choices for your stay based on our traveller data. Other good choices within a few miles include The Yellow Penthouse and Hotel Jefe at Ojos Locos.
How many hotels should I expect to find near Santa Fe Medical Center?
Expedia has 17 hotels and other accommodation options within a mile from Santa Fe Medical Center.
If I need to cancel the hotel reservation for my stay near Santa Fe Medical Center, will I receive a refund?
Yes! Most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to view the top deals on offer near Santa Fe Medical Center.
What can I see and do near Santa Fe Medical Center?
You might want to spend some time browsing the exhibits at The Neon Museum, Mob Museum or Old Las Vegas Mormon Fort State Historic Park. First AME Church, Harrison House and West Las Vegas Arts Center are monuments to see when you're exploring the area around Santa Fe Medical Center. You can watch performances at Smith Center for the Performing Arts, West Las Vegas Library Theatre and Lowden Theater if you're interested in local theatre.