A coastal town with colorful buildings, a mountain range in the background, and boats in the water.

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Check availability on Samos Luxury Hotels

Tonight
9 Oct - 10 Oct
Tomorrow
10 Oct - 11 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Samos luxury hotels

A modern resort with a central pool, lounge areas, and mountain views.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A spa area with two massage tables, a stone floor, and a bamboo partition.

1. Casa Cook Samos

Casa Cook Samos
Samos
  • Beachfront luxury meets spa indulgence at Casa Cook Samos, where Mediterranean elegance awaits.
฿7,084
฿8,325 total
includes taxes & fees
21 Oct - 22 Oct
Casa Cook Samos
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A serene outdoor setting with a pool, a person in a white dress, and a view of the sea.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.

2. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Private beachfront luxury meets seaside serenity at this adults-only Samos resort offering spa indulgences and ocean-view dining.
฿5,574
฿6,671 total
includes taxes & fees
18 Oct - 19 Oct
Proteas Blu Resort - Adults Only
An infinity pool with lounge chairs and a view of a coastal town.
A modern multi-story building with a landscaped courtyard, featuring a mix of flat and sloped roofs, and a variety of plants and trees.
A modern outdoor seating area with a view of a coastal town and mountains.
A modern interior with a dark wood reception desk, a sofa, a large abstract painting, and a potted plant.

3. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
฿5,264
฿6,331 total
includes taxes & fees
24 Oct - 25 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
View all properties

Top Samos Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"A gorgeous property, great location, courteous staff… would def stay there again!! Perfect room!!😊"
Athanasios 2-night trip
Posted 13 days ago
Doryssa Seaside Resort

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Samos?
Arrange a flight into Samos (SMI-Samos Intl.) Airport or Ikaria Island (JIK) Airport, and then treat yourself to a stay at one of 6 luxurious hotels. Samos has some interesting things to see and do including Port of Samos and Samos Port, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Samos?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your trip.
How many luxury hotels are there in Samos?
Lie in the lap of luxury during your getaway to Samos in one of Expedia's 6 luxury hotels.
When can I expect good weather in Samos?
Planning for the weather is an important factor for making your trip to Samos a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 13°C. Average annual precipitation for Samos is 837 mm.
What's there to see and do in Samos?
Enjoy Samos and visit Port of Samos, Samos Port and Gagou Beach. If you have extra time while you're in the area, you might want to see Psili Amos Beach and Glicorisa Beach.