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Find hotels in Panacea, FL from ฿2,777

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Top 10 Panacea hotels and places to stay

Our top choices for Panacea hotels

The Lodge at Wakulla Springs

3.0 star property
9.4 out of 10, Exceptional, (974)
"We love staying here!!"
The Lodge at Wakulla Springs

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (916)
"We absolutely love this venue and stay here when we visit our family every year! "
The price is ฿3,768
฿4,202 total
includes taxes & fees
11 Sept - 12 Sept
Best Western Wakulla Inn & Suites

Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1002)
"An enjoyable stay. Thank you."
The price is ฿4,515
฿5,165 total
includes taxes & fees
27 Aug - 28 Aug
Wildwood Inn

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (111)
"Needed a place for overnight on our journey. Small & quaint. Rooms are clean & have coffee, fridge & microwave . No one on property but there is an available #to call if needed. Would stay again."
The Panacea Motel

Franklin Inn

2.0 star property
7.8 out of 10, Good, (432)
"Food options are close and very good"
The price is ฿2,777
฿3,069 total
includes taxes & fees
27 Aug - 28 Aug
Franklin Inn

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (352)
"The area around the resort is beautiful. it was Sunday, was supposed to have breakfast in the restaurant per its menu in the room, but it was not available. The room was not clean, but the sheets and towels were good. "
The price is ฿5,165
฿5,707 total
includes taxes & fees
27 Aug - 28 Aug
St James Bay Golf & Pickleball Resort

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very good, (34)
" Clean rooms :) "
The price is ฿5,863
฿6,479 total
includes taxes & fees
27 Aug - 28 Aug
The Moorings Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Top Panacea Hotel Reviews

More cheap stays in Panacea

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Frequently asked questions

Where is the best place to stay in Panacea?

Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

What's the best dog-friendly place to stay in Panacea?

The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

How is it to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 198 hotels and other accommodation options to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Wilson Beach and Alligator Point Beach. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Bald Point State Park and Public Beach Access. Take a look at what more there is to see and do in Expedia's Panacea guide.

What's the seasonal weather in Panacea?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.