A cannon on a brick platform by a river, with a steamboat in the background.

Find hotels in New Madrid, MO from ฿2,050

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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for New Madrid hotels

Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (479 reviews)
"Nice!"
United States
theresa
The price is ฿3,063
฿3,468 total
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG
Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (68 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is ฿2,773
฿3,167 total
includes taxes & fees
17 Jul - 18 Jul
Super 8 By Wyndham Marston
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (592 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is ฿3,594
฿4,069 total
includes taxes & fees
13 Aug - 14 Aug
Hampton Inn Sikeston
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (786 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is ฿1,899
฿2,050 total
includes taxes & fees
19 Jul - 20 Jul
New Orleans Inn Portageville
Standard Room, 2 Double Beds, Non Smoking | Blackout curtains, iron/ironing board (on request), free WiFi

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (501 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is ฿2,043
฿2,344 total
includes taxes & fees
31 Jul - 1 Aug
Reelfoot Lake Inn
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (99 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is ฿3,683
฿4,170 total
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn & Suites by Marriott Sikeston
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ฿4,253
฿4,815 total
includes taxes & fees
23 Jul - 24 Jul
TownePlace Suites by Marriott Sikeston
Free WiFi, bed sheets

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (125 reviews)
"Quiet safe area."
United States
Frank
The price is ฿1,758
฿2,184 total
includes taxes & fees
14 Aug - 15 Aug
Travel Inn Marston I-55 by Hotel O
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

New Madrid Historical Museum

8.2/10 (36 reviews)
Explore the powerful 1811-1812 earthquakes that reshaped America's heartland at this historic museum. Engage with knowledgeable curators while viewing artefacts from Native American cultures and the Civil War.
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Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
A cannon on a brick platform by a river, with a steamboat in the background.

Top New Madrid Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"My 21 year old son stayed at this Hampton Inn on his way back to college in IL. He enjoyed the gym, the indoor pool, the large selection of breakfast items, and the close proximity to I-55. The room was clean and the staff was friendly, even to a 21 year old young man traveling alone. Thank you for a wonderfully positive experience!"
Caiden 1-night trip
Posted 4 hours ago
Hampton Inn Sikeston

More cheap stays in New Madrid

New Orleans Inn Portageville

New Orleans Inn Portageville

600 US-61 Portageville MO
The price is ฿1,899 per night from 19 Jul to 20 Jul
฿1,899
฿2,050 total
19 Jul - 20 Jul
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Holiday Inn Express & Suites Sikeston Southwest by IHG and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 59 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your itinerary are Mississippi River and River Ridge Winery. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for New Madrid is 1537 mm.