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Our top choices for National Great Rivers Museum hotels

Exterior
Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
5.4 km from National Great Rivers Museum
9.0 out of 10, Wonderful, (644)
"The staff were very professional and friendly. The breakfast had a great selection."
United States
Melissa
The price is ฿3,586
฿4,087 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites St. Louis/Alton
Exterior
Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel
2.5 star property
5.2 km from National Great Rivers Museum
8.2 out of 10, Very good, (1002)
"Staff was excellent when checking in"
United States
larry
The price is ฿2,407
฿2,743 total
includes taxes & fees
18 Jan - 19 Jan 2026
Best Western Plus Parkway Hotel
Exterior
Bel Air Motel

Bel Air Motel

Bel Air Motel
3.5 star property
4.1 km from National Great Rivers Museum
8.6 out of 10, Excellent, (196)
"Great place super clean. Only thing missing no coffee and our room could have had a nice bistro table to sit at"
United States
James
The price is ฿2,485
฿3,041 total
includes taxes & fees
1 Jan - 2 Jan 2026
Bel Air Motel
Free daily buffet breakfast
Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
5.2 km from National Great Rivers Museum
9.2 out of 10, Wonderful, (163)
"Staff and location were perfect"
United States
Ileta
The price is ฿3,583
฿4,084 total
includes taxes & fees
3 Jan - 4 Jan 2026
Holiday Inn Express and Suites Alton St Louis Area by IHG
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
3.9 km from National Great Rivers Museum
7.8 out of 10, Good, (762)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
The price is ฿2,647
฿3,017 total
includes taxes & fees
25 Jan - 26 Jan 2026
The Great Rivers, an Ascend Collection Hotel
Lobby
Comfort Inn Alton near I-255

Comfort Inn Alton near I-255

Comfort Inn Alton near I-255
2.5 star property
3.9 km from National Great Rivers Museum
7.6 out of 10, Good, (508)
"Perfect accommodations for a brief overnight stay. "
United States
Steffany
The price is ฿2,513
฿2,865 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Alton near I-255
Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham Alton

Super 8 by Wyndham Alton

Super 8 by Wyndham Alton
2.0 star property
5.4 km from National Great Rivers Museum
7.0 out of 10, Good, (872)
"The place was clean and plenty of room for our boat"
United States
David
The price is ฿2,831
฿3,227 total
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Alton
Premium bedding, pillow-top beds, blackout curtains, iron/ironing board
Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis
2.0 star property
12.4 km from National Great Rivers Museum
6.2 out of 10, (246)
"Overall the stay was adequate, right off the highway so convenient."
United States
Henry
The price is ฿2,159
฿2,482 total
includes taxes & fees
11 Jan - 12 Jan 2026
Econo Lodge Inn & Suites Granite City - St. Louis
Lobby lounge
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
2.5 star property
14.9 km from National Great Rivers Museum
9.2 out of 10, Wonderful, (488)
"This hotel was well kept,the breakfast was excellent. Stsff was friendly. "
United States
Dennis M
The price is ฿3,523
฿3,910 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Lobby
Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach
2.0 star property
15.3 km from National Great Rivers Museum
6.2 out of 10, (571)
"Bed was soooooooo comfortable and front desk guy that checked me in was great as well "
United States
Maurice
The price is ฿2,032
฿2,255 total
includes taxes & fees
18 Jan - 19 Jan 2026
Days Inn by Wyndham Pontoon Beach
Exterior
Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area
2.0 star property
12.4 km from National Great Rivers Museum
6.4 out of 10, (15)
"Its nice here"
United States
Sheila
The price is ฿2,108
฿2,297 total
includes taxes & fees
7 Jan - 8 Jan 2026
Budget Motel Granite City/St Louis Area
Lobby sitting area
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
15.5 km from National Great Rivers Museum
8.6 out of 10, Excellent, (806)
"Staff and very nice, good breakfast, soft bed…. I would definitely stay again "
United States
LaSonya
The price is ฿2,689
฿2,985 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Pontoon Beach
Blackout curtains, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
14.3 km from National Great Rivers Museum
7.8 out of 10, Good, (583)
"Yes, very good, yes good breakfast, yes truck parking."
United States
mark
The price is ฿1,840
฿2,083 total
includes taxes & fees
1 Jan - 2 Jan 2026
Red Lion Inn & Suites Pontoon Beach
Free daily buffet breakfast
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
17.4 km from National Great Rivers Museum
9.2 out of 10, Wonderful, (823)
"Always a good stay here!"
United States
Chelsie
The price is ฿3,649
฿4,196 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
17.5 km from National Great Rivers Museum
8.6 out of 10, Excellent, (650)
"The room was very clean and the staff is always friendly "
United States
Lynn
The price is ฿2,863
฿3,291 total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Hearth Inn & Suites Edwardsville St. Louis
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
17.3 km from National Great Rivers Museum
8.4 out of 10, Very good, (810)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
The price is ฿3,218
฿3,700 total
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Inn Edwardsville - St. Louis
Exterior
Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area

Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area

Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
2.0 star property
15.4 km from National Great Rivers Museum
5.6 out of 10, (657)
"It was good "
United States
Todd
The price is ฿1,925
฿2,137 total
includes taxes & fees
14 Jan - 15 Jan 2026
Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
Free daily self-service breakfast
La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
15.6 km from National Great Rivers Museum
7.6 out of 10, Good, (514)
"The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. "
United States
Kari
The price is ฿2,800
฿3,219 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham Pontoon Beach
Reception
Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville
2.5 star property
18.3 km from National Great Rivers Museum
7.4 out of 10, Good, (73)
"We enjoyed our stay"
United States
Susan
The price is ฿3,328
฿3,726 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hampton Inn & Suites St. Louis-Edwardsville
Breakfast area
Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis
2.5 star property
19.2 km from National Great Rivers Museum
7.6 out of 10, Good, (1000)
"Hotel very old, not taken care of. Poor breakfast, OJ was rotten in the dispenser. Do not recommend "
United States
Thomas
The price is ฿2,095
฿2,475 total
includes taxes & fees
7 Jan - 8 Jan 2026
Quality Inn Florissant - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top National Great Rivers Museum Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"We didn’t eat breakfast. Room was clean and tidy. Not enough conditioner in the container to cleanse hair. Only complaint. "
Heather 1-night trip
Posted 2 days ago
Hyatt Regency St. Louis at The Arch

Hotels near other National Great Rivers Museum attractions

Ellis Island

Commune with nature and explore the great outdoors at Ellis Island during your travels in West Alton. While you're in the area, wander around the parks.
See properties

Fast Eddie's Bon Air

4.7/5 (3 reviews)
You can search for that perfect souvenir at Fast Eddie's Bon Air during your visit to Alton. Visit the shops in this family-friendly area or simply enjoy its restaurants.
See properties

Frequently asked questions

What's the area like around National Great Rivers Museum?
National Great Rivers Museum is located in an area of Alton that travellers like for its university setting. You'll find 24 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to National Great Rivers Museum?
Best Western Plus Pontoon Beach is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. You'll find it 9.6 mi (15.5 km) from National Great Rivers Museum. Other good choices around the area include Hyatt Regency St. Louis at The Arch and Renaissance St. Louis Airport Hotel.
How many hotels will I be able to find close to National Great Rivers Museum?
Expedia has 24 hotels and other accommodation options a few miles from National Great Rivers Museum.
If I need to cancel the hotel reservation for my stay near National Great Rivers Museum, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near National Great Rivers Museum.
What can I see and do near National Great Rivers Museum?
You'll want to browse the exhibits at Historic Museum of Torture Devices and Alton Prison. You can enjoy nature at Ellis Island, Jones-Confluence Point State Park or Columbia Bottom Conservation Area. Looking for a little shopping break? A trip to Fast Eddie's Bon Air, Alton Square Mall and Mineral Springs Mall might be just the ticket while you're in the area around National Great Rivers Museum.