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Our top choices for Museum of Us hotels

Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from Museum of Us
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Memory-foam beds, blackout curtains, iron/ironing board, free WiFi
Stay Classy Hostel

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 2.3 km from Museum of Us
9.6 out of 10, Exceptional, (789)
"Good place to stay "
United States
sai
Stay Classy Hostel
Suite, 1 King Bed with Sofa bed, City View | View from room
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.5 km from Museum of Us
9.4 out of 10, Exceptional, (1006)
"The hotel and staff are amazing!"
United States
Barbara
The price is ฿4,935
฿5,721 total
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott Vacation Club®, San Diego
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 2.4 km from Museum of Us
9.4 out of 10, Exceptional, (1006)
"Great location "
United States
Mohammad
The price is ฿3,045
฿4,427 total
includes taxes & fees
25 Jan - 26 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
2.8 km from Museum of Us
9.4 out of 10, Exceptional, (1362)
"Amazing hotel, great staff and awesome food!"
United States
michael
The price is ฿7,107
฿8,155 total
includes taxes & fees
30 Dec - 31 Dec
Lafayette Hotel & Club
Exterior
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 2 km from Museum of Us
9.2 out of 10, Wonderful, (633)
"Great stay"
United States
Angelica
The price is ฿4,935
฿5,721 total
includes taxes & fees
4 Jan - 5 Jan 2026
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Standard Quadruple Room, Mixed Dorm | Shared kitchen facilities | Fridge, microwave, stovetop, toaster
Gaslamp Hostel

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 2.2 km from Museum of Us
9.2 out of 10, Wonderful, (542)
"Great location with clean, comfortable rooms. Amazing ambiance and professional staff. I would stay hear again."
United States
Anthony Michael
Gaslamp Hostel
Premium bedding, pillow-top beds, desk, laptop workspace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 2.4 km from Museum of Us
9.2 out of 10, Wonderful, (612)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is ฿3,403
฿4,845 total
includes taxes & fees
3 Jan - 4 Jan 2026
Sentral Gaslamp Quarter
3 restaurants, breakfast, lunch, dinner served; seafood
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 2.6 km from Museum of Us
9.2 out of 10, Wonderful, (1004)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is ฿8,535
฿11,526 total
includes taxes & fees
19 Jan - 20 Jan 2026
Pendry San Diego
Meeting facility
Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
2.4 km from Museum of Us
9.2 out of 10, Wonderful, (644)
"Loved this hotel. Near everything and the kids loved it. Staff was super friendly. "
United States
Wendy
The price is ฿8,038
฿9,330 total
includes taxes & fees
5 Jan - 6 Jan 2026
Residence Inn by Marriott San Diego Downtown/Bayfront
Lobby lounge
TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown
3.0 star property
1.4 km from Museum of Us
9.0 out of 10, Wonderful, (1002)
"Good breakfast, clean and comfortable rooms and attentive, pleasant staff, all at a great value."
United States
charles
The price is ฿3,838
฿4,450 total
includes taxes & fees
18 Jan - 19 Jan 2026
TownePlace Suites by Marriott San Diego Downtown
City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 1.6 km from Museum of Us
9.0 out of 10, Wonderful, (144)
"Great place to stay "
United States
Jacorey
The price is ฿3,786
฿4,390 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott San Diego Downtown Little Italy
Lobby
Best Western Plus Bayside Inn

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
2 km from Museum of Us
9.0 out of 10, Wonderful, (1000)
"Great area, staff was attentive and the balcony was an unexpected surprise! Great hotel! "
United States
Armando
The price is ฿3,945
฿4,566 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Bayside Inn
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 2 km from Museum of Us
9.0 out of 10, Wonderful, (1019)
"Great hotel, excellent location, excellent view on rooftop!"
United States
Rajeev
The price is ฿3,662
฿4,166 total
includes taxes & fees
18 Jan - 19 Jan 2026
Gaslamp Plaza Suites
Presidential Suite, 2 Bedrooms | Living room | 36-inch LCD TV with digital channels, TV, pay films
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel
4.0 star property
1.9 km from Museum of Us
9.0 out of 10, Wonderful, (881)
"Friendly staff throughout stay and clean rooms"
United States
Alvin
The price is ฿3,352
฿5,146 total
includes taxes & fees
4 Jan - 5 Jan 2026
Alma San Diego Downtown, a Tribute Portfolio Hotel
Outdoor pool, pool loungers
Westgate Hotel

Westgate Hotel

Westgate Hotel
4.5 star property
2 km from Museum of Us
9.0 out of 10, Wonderful, (1003)
"Everything about the Hotel including staff was fantastic"
Canada
Donna
The price is ฿4,986
฿6,860 total
includes taxes & fees
30 Dec - 31 Dec
Westgate Hotel
Lobby
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego
5.0 star property
1.9 km from Museum of Us
9.0 out of 10, Wonderful, (1003)
"I loved my stay here ! I would definitely stay here again . The staff were pleasant and welcoming. The amenities were great ! The only complaint I have is I wish parking was included in our stay if you’re staying at the hotel as a guest "
United States
Vanessa
The price is ฿9,279
฿10,759 total
includes taxes & fees
5 Jan - 6 Jan 2026
The US Grant, a Luxury Collection Hotel, San Diego
Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection
4.0 star property
2 km from Museum of Us
9.0 out of 10, Wonderful, (1199)
"Modern decor, great restaurant, convenient to all attractions in San Diego."
United States
Nelson
The price is ฿5,103
฿7,357 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Republic San Diego, Autograph Collection
Terrace/patio
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
2.3 km from Museum of Us
9.0 out of 10, Wonderful, (1080)
"Loved my stay! Def plan to stay here again "
United States
Lizbeth Flores
The price is ฿3,693
฿4,282 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Marina District, 2.5 km from Museum of Us
9.0 out of 10, Wonderful, (2712)
"Beautiful hotel, far surpasses any expectation of an older Victorian hotel. I highly recommend this stay! "
United States
Jessica
The Horton Grand, Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Museum of Us Hotel Reviews

Pendry San Diego

Pendry San Diego

10/10 Excellent
"The front desk manager was a pleasure to deal with. We are Elwood Members at the Pendry in Newport and we were do impressed with how we were treated, the staff and the beautiful room we stayed in. Highly recommend to stay at this property. If you want 5 star service, you will get it at this Pendry!"
Darin 1-night trip
Posted 1 day ago
Pendry San Diego

Hotels near other Museum of Us attractions

California Tower

California Tower

Learn about the local history of San Diego with a stop at California Tower. Discover the area's top-notch restaurants and its acclaimed art galleries.
See properties
Old Globe Theater featuring a garden and wildflowers

Old Globe Theater

You can enjoy a show at Old Globe Theater during your stay in San Diego. Discover the area's top-notch restaurants and its acclaimed theatre scene.
See properties

Frequently asked questions

What's the area like around Museum of Us?
Museum of Us is located in an area of San Diego known for its beautiful ocean views, array of dining options and popular zoo. If you're looking for a convenient place to stay, take a look at the 190 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Museum of Us?
The DEXTRO Little Italy, BW Premier Collection is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.9 mi (1.5 km) from Museum of Us. Other good choices within a short distance include Courtyard by Marriott San Diego Downtown Little Italy and Holiday Inn Express San Diego Downtown by IHG.
How many hotels will I find near Museum of Us?
Expedia has 190 hotels and other accommodation options within a mile from Museum of Us.
If I need to cancel the hotel reservation for my stay near Museum of Us, will I receive a refund?
Yes, the majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Museum of Us.
What can I see and do near Museum of Us?
San Diego Museum of Art, San Diego Natural History Museum and San Diego Air and Space Museum feature captivating exhibits. Hotel del Coronado, Casa de Balboa and Star of India are monuments to see when you're exploring the area around Museum of Us. You can watch performances at Old Globe Theater, San Diego Civic Theatre and The Rady Shell at Jacobs Park if you're interested in local theatre.