Midtown Travel Guide
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Narrated Trolley Tour
St. Louis Ghost Tour: Sinister Sins & Shadows
St Louis Self-Guided Driving and Walking Audio Tour
St. Louis: Museum of Illusions Entry Ticket
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch
Top hotels in Midtown
Element St. Louis Midtown
Clean room, staff, location
Reviewed on 30 Dec 2025
Hyatt Regency St. Louis at The Arch
Clean, comfortable room. Great location.
Reviewed on 5 Jan 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Awesome location to the Gateway National Arch, Economy Museum, and dome. Loved the friendly staff! The building was very secure and safe feeling with my family in the city. The breakfast area is very well kept and kept stocked well.
Reviewed on 5 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hotel and room were very clean
Reviewed on 4 Jan 2026
21C Museum Hotel St Louis
6 day stay was wonderful
Reviewed on 3 Jan 2026
Clayton Plaza Hotel & Extended Stay
The room was very cozy and welcoming. The staff was great and friendly from checking in to the breakfast host to checking out.
Reviewed on 5 Jan 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
