Midtown Travel Guide
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis: Museum of Illusions Entry Ticket
St. Louis Premium Small Group Tour With Arch & River Cruise
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Driving Tour with Boat Ride & Arch
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Midtown
Element St. Louis Midtown
Breakfast was good and fresh but there needs to be a kids waffle or on cake option. Park situation needs better explanation when booking no good option outside of valet. Overall great experience.
Reviewed on 10 Apr 2026
Residence Inn by Marriott St Louis Downtown
Staff was great. The hotel could use work. One of the t.v.’s in the room didn’t work. Door stuck in bathroom. Pool area not stocked with towels and could be cleaner. Breakfast was good.
Reviewed on 8 Apr 2026
Clayton Plaza Hotel & Extended Stay
Staff was friendly and courteous going out of their way to satisfy you. Breakfast was the only downfall.
Reviewed on 11 Apr 2026
Drury Plaza Hotel St. Louis at the Arch
Food was good, rooms were clean, people are friendly. Would highly recommended
Reviewed on 11 Apr 2026
Pear Tree Inn St. Louis Near Union Station
The breakfast was delicious and all support staff were terrific. The bathroom was a little dirty and the towel handle was just sitting on the wall mount and fell off the moment i first dried my hands. Wasnt a big deal but was odd. It was a very busy weekend for them and i understand that not all ...
Reviewed on 10 Apr 2026
Hyatt Regency St. Louis at The Arch
Taller toilets! I feel i’m in elementary school in the bathroom there.
Reviewed on 10 Apr 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
