Midtown Travel Guide

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit

Things to do


Top hotels in Midtown

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
The price is ฿4,366 per night from 22 Oct to 23 Oct
฿4,366
฿5,105 total
22 Oct - 23 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
9/10 Wonderful! (599 reviews)
"I loved this place, the staff and even the people staying there were all super friendly!!"

Reviewed on 30 Sept 2025

Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave, St. Louis, MO
The price is ฿3,687 per night from 12 Oct to 13 Oct
฿3,687
฿4,385 total
12 Oct - 13 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,004 reviews)
"Overall, it was great. The breakfast was good, with many options. Staff service was good; however, they should smile more and be more attentive to guests' questions, responding kindly."

Reviewed on 30 Sept 2025

Residence Inn by Marriott St Louis Downtown
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is ฿3,331 per night from 19 Oct to 20 Oct
฿3,331
฿3,880 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,947 reviews)
"Great breakfast with homemade omelets. Even the cook was friendly and joking with us. Rooms were clean, great comfortable bed. Shower was large and took shower without getting hair wet(a plus to me). Humidity controlled mirror helped to get us in and out fast. Overall excellent service."

Reviewed on 30 Sept 2025

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
The price is ฿4,398 per night from 19 Oct to 20 Oct
฿4,398
฿5,143 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,122 reviews)
"I walked to the Arch a few times. The rooftop was amazing."

Reviewed on 30 Sept 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
The price is ฿3,946 per night from 2 Nov to 3 Nov
฿3,946
฿4,653 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,971 reviews)
"Great stay"

Reviewed on 30 Sept 2025

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
The price is ฿2,911 per night from 20 Oct to 21 Oct
฿2,911
฿3,426 total
20 Oct - 21 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (2,703 reviews)
"The staff was pleasant, the room was clean, and the breakfast was good."

Reviewed on 1 Oct 2025

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Midtown

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The Gate

While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis showing interior views

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Downtown West
Lafayette Square featuring a house and a park

Lafayette Square

The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.

Lafayette Square
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Shaw

Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
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The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove


Midtown Travel Guide