Medical Center District Travel Guide

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,919 per night from 23 Aug to 24 Aug
฿2,919
฿3,450 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ฿2,947 per night from 28 Aug to 29 Aug
฿2,947
฿3,484 total
28 Aug - 29 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Medical Center San Antonio
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿2,958 per night from 25 Aug to 26 Aug
฿2,958
฿3,497 total
25 Aug - 26 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ฿3,539 per night from 20 Sept to 21 Sept
฿3,539
฿4,205 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,151 reviews)
"Please don’t expect any help or flexibility from this Hotel. I notified them within 24 hours regarding my cancellation and they wouldn’t cooperate. Unlike any other hotel chain, they would want you to pay in advance. I visit the area a lot for business and I’ll never stay in that property."

Reviewed on 19 Aug 2026

San Antonio Marriott Northwest Medical Center
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is ฿2,355 per night from 7 Sept to 8 Sept
฿2,355
฿3,441 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is ฿4,207 per night from 30 Aug to 31 Aug
฿4,207
฿4,973 total
30 Aug - 31 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,132 reviews)
"An exemplary experience at a family owned 4 star establishment."

Reviewed on 20 Aug 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

Uptown

If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.



Medical Center District Travel Guide