Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience
฿972
per adult
96% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
฿5,880
per adult
100% of travellers recommend
San Antonio: Witte Museum Admission Ticket
฿558
per adult
84% of travellers recommend
Dining at Hard Rock Cafe San Antonio
฿1,314
per traveller
74% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
฿1,051
per adult
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,946 per night from 6 Jul to 7 Jul
฿2,946
฿3,482 total
6 Jul - 7 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,452 reviews)
"Muy tranquilo. Tiene todo lo necesario"
Reviewed on 4 Jul 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ฿3,852 per night from 19 Jul to 20 Jul
฿3,852
฿4,577 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,098 reviews)
"Very nice hotel Had a great experience"
Reviewed on 2 Jul 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿2,986 per night from 26 Jul to 27 Jul
฿2,986
฿3,529 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,372 reviews)
"Friendly staff clean rooms"
Reviewed on 4 Jul 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is ฿2,953 per night from 17 Jul to 18 Jul
฿2,953
฿3,490 total
17 Jul - 18 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,008 reviews)
"A well-maintained interior property, building exterior is a little rough. Staff was very helpful and the property is secured. Enjoyed the stay."
Reviewed on 4 Jul 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is ฿4,246 per night from 19 Jul to 20 Jul
฿4,246
฿5,019 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,848 reviews)
"Everyone was very professional and helpful. Very much friendly and amazing"
Reviewed on 4 Jul 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is ฿2,956 per night from 6 Jul to 7 Jul
฿2,956
฿3,494 total
6 Jul - 7 Jul
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,455 reviews)
"Everything was meh..Also for some reason after 10:30pm the Valet guy didn't seem like he wanted to go get my car. He said "most places a closed.""
Reviewed on 5 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.
