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Check availability on Louisville Spa Hotels

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Louisville hotels with a spa

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3895)
"Great place to stay! "
United States
Rochelle
The price is ฿4,137
฿4,868 total
includes taxes & fees
5 Jan - 6 Jan 2026
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1744)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is ฿5,189
฿6,106 total
includes taxes & fees
2 Jan - 3 Jan 2026
Omni Louisville Hotel
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very good, (1003)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is ฿3,383
฿4,376 total
includes taxes & fees
29 Dec - 30 Dec
Caesars Southern Indiana - A Caesars Rewards Destination
Full-sized fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is ฿5,121
฿7,496 total
includes taxes & fees
30 Dec - 31 Dec
The Reserve on Main
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is ฿4,314
฿5,231 total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (57)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is ฿4,208
฿4,884 total
includes taxes & fees
28 Dec - 29 Dec
Central Park Bed & Breakfast
Bar (on property)
Pillow and Paddock B&B

Pillow and Paddock B&B

Pillow and Paddock B&B
3.5 star property
La Grange
10.0 out of 10, Exceptional, (52)
"Courteous staff and the room was outstanding. It was our second stay at the inn. Everything is first class. We highly recommend it."
United States
Fran
The price is ฿11,557
฿12,740 total
includes taxes & fees
5 Jan - 6 Jan 2026
Pillow and Paddock B&B
Nightclub
Bourbon Manor B&B

Bourbon Manor B&B

Bourbon Manor B&B
4.0 star property
Bardstown
9.8 out of 10, Exceptional, (76)
"Clean room, friendly staff"
United States
Heather
Bourbon Manor B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisville Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Everything was amazing from Check in to check out"
William 1-night trip
Posted 4 days ago
Galt House Hotel Trademark Collection by Wyndham

Frequently asked questions

Looking for a spa hotel in Louisville?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers love the riverfront in Louisville. Make sure you pay a visit to the museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Louisville?
Galt House Hotel Trademark Collection by Wyndham is a top spa hotel featuring 4 restaurants, a fitness centre, a hair salon and a bar. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and manicures/pedicures. In-room massages are also available. Other popular spa hotels in Louisville include Omni Louisville Hotel and 21c Museum Hotel Louisville.
How many spa hotels will I find in Louisville?
Among Expedia's 2237 accommodation options in Louisville, there are 5 spa hotels.
What's there to see and do in Louisville?
Experience Louisville and visit KFC Yum Center, Whiskey Row and Belle of Louisville. If you have a little extra time during your trip, you might want to check out Riverfront Plaza Belvedere and Evan Williams Bourbon Experience.
What is a Louisville spa hotel?
Spa hotels in Louisville provide lodging and have an on-site spa which offers services such as massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.