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Check prices for these dates

In two weeks
9 Jan - 11 Jan
In two months
20 Feb - 22 Feb
In three months
20 Mar - 22 Mar
In four months
17 Apr - 19 Apr

Our top choices for Los Anastacios holiday rentals

House, 2 Bedrooms | Terrace/patio
Cabanas Rio Encantado

Cabin in Caldera

Cabanas Rio Encantado
3.0 star property
9.4 out of 10, Exceptional, (40)
"This was our favorite place. Clean, gorgeous grounds, comfortable rooms, killer pool, riverside, very accommodating host. Love, love, love."
United States
Kristin
The price is ฿3,182
฿3,500 total
includes taxes & fees
13 Jan - 14 Jan 2026
Cabanas Rio Encantado
Front of property
Aires frescos de Boquete

Condo resort in Alto Boquete

Aires frescos de Boquete
2.0 star property
9.0 out of 10, Wonderful, (4)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is ฿1,603
฿1,764 total
includes taxes & fees
28 Dec - 29 Dec
Aires frescos de Boquete
Exterior
Linda Vista Cabins

Cabin in Alto Boquete

Linda Vista Cabins
3.0 star property
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is ฿1,558
฿1,714 total
includes taxes & fees
3 Jan - 4 Jan 2026
Linda Vista Cabins
Tree House, Mountain View | View from room
Lucero - Luxury Treehouses

Treehouse in Jaramillo

Lucero - Luxury Treehouses
3.5 star property
8.6 out of 10, Excellent, (4)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
The price is ฿7,405
฿8,145 total
includes taxes & fees
4 Jan - 5 Jan 2026
Lucero - Luxury Treehouses
43-inch Smart TV with digital channels
Casa Mate by Villa Alejandro

Villa in Los Naranjos

Casa Mate by Villa Alejandro
3.5 star property
The price is ฿2,688
฿3,547 total
includes taxes & fees
7 Jan - 8 Jan 2026
Casa Mate by Villa Alejandro
Honeymoon Studio, Hot Tub, Valley View | Egyptian cotton sheets, premium bedding, Tempur-Pedic beds
Villa Alejandro

Villa in Boquete

Villa Alejandro
3.5 star property
8.8 out of 10, Excellent, (130)
"Priced right, easy walk to town, safe, quiet & overall great stay! "
United States
John
Villa Alejandro
Standard Apartment, 2 Bedrooms | Private kitchen | Microwave, coffee/tea maker
Peace N' Green

Apartment in David

Peace N' Green
3.0 star property
The price is ฿1,474
฿1,621 total
includes taxes & fees
27 Dec - 28 Dec
Peace N' Green
Front of property
Aparthotel Los Pinos

Apartment in Boquete

Aparthotel Los Pinos
2.5 star property
8.4 out of 10, Very good, (16)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
The price is ฿3,499
฿3,849 total
includes taxes & fees
25 Dec - 26 Dec
Aparthotel Los Pinos
Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub
Casa Reina by Villa Alejandro

Aparthotel in Boquete

Casa Reina by Villa Alejandro
4.0 star property
8.6 out of 10, Excellent, (14)
"The property is outside of the town proper, so is quiet and it is possible to see wildlife. The room was extremely clean and comfortable, and the staff was welcoming and friendly. The view from the balcony was amazing!"
Canada
Catherine
The price is ฿3,111
฿4,013 total
includes taxes & fees
5 Jan - 6 Jan 2026
Casa Reina by Villa Alejandro
Condo, 2 Bedrooms | 2 bedrooms, iron/ironing board, free WiFi
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Condo in El Tropezón

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
The price is ฿3,998
฿7,589 total
includes taxes & fees
19 Jan - 20 Jan 2026
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
Design Suite, 1 King Bed, Mountain View | Premium bedding, down duvets, individually decorated
El Cielo by Villa Alejandro

Apartment in Boquete

El Cielo by Villa Alejandro
3.5 star property
9.4 out of 10, Exceptional, (91)
"We stayed here for a week while in Boquete and already plan to stay here when we return in a few months. The accomodation was clean with a well-stocked kitchen. The location is perfect to walk around the wonderful shops and restaurants in Boquete. The management team was very responsive to questions, ect. The accomodation is bright and airy and is perfect for short and long-term stays. We cannot recommend El Cielo enough!"
United States
Susan
El Cielo by Villa Alejandro
Property grounds
Downtown Suites

Aparthotel in El Tropezón

Downtown Suites
3.0 star property
9.0 out of 10, Wonderful, (101)
"Good location, nice rooms, great value."
United States
Robert
Downtown Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Los Anastacios Hotel Reviews

Hampton by Hilton David

Hampton by Hilton David

10/10 Excellent
"Staff was awesomr"
CHRISTIAN 1-night trip
Posted 4 days ago
Hampton by Hilton David

Find out more about Los Anastacios

Search for holiday rentals in Los Anastacios on Expedia! You can easily find your home rentals, villas, holiday apartments in Los Anastacios using one of the methods below:

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Look no further and take a look at our great range of rental properties in Los Anastacios!

Frequently asked questions

Can I find a holiday rental in Los Anastacios?

Yes, there are holiday rentals close to the most popular sights in Los Anastacios, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Los Anastacios?

While you're exploring the area, Parque de las Madres and Miguel de Cervantes Saavedra Park are a couple of picturesque spots to get outside and enjoy nature. In the wider area, you’ll find Plaza El Terronal and Boquete Library.

What are holiday rentals like in Los Anastacios?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Los Anastacios. Holiday rentals feature amenities such as kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of safety away from public hotel lifts and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is a popular choice for a family getaway.