Find hotels in Ladys Island, SC from ฿2,080

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 Ladys Island hotels and places to stay

Our top choices for Ladys Island hotels

Montage Palmetto Bluff

5.0 star property
9.6 out of 10, Exceptional, (239)
"Great property and staff is amazing!! Super service!"
The price is ฿16,463
฿20,063 total
includes taxes & fees
22 Sept - 23 Sept
Montage Palmetto Bluff

City Loft Hotel

3.5 star property
9.4 out of 10, Exceptional, (733)
"The property was immaculate and the staff was friendly! "
The price is ฿5,317
฿6,316 total
includes taxes & fees
31 Aug - 1 Sept
City Loft Hotel

Rhett House Inn

4.0 star property
9.2 out of 10, Wonderful, (616)
"The Rhett house takes you to great southern hospitality at its best. The Inn sits on a corner of downtown that is walkable to many restaurants and steps away from the bay. The checkin was easy and offerings of cheese tray followed by deserts was a great bonus to the spacious cottage room we had. The next morning we sat on the veranda for a delightful breakfast. The Rhett House Inn is a must for hospitality and location."
The price is ฿6,006
฿7,928 total
includes taxes & fees
30 Aug - 31 Aug
Rhett House Inn

Beaufort Inn

3.5 star property
9.2 out of 10, Wonderful, (1004)
"Beautiful Inn in a great location. "
Beaufort Inn

Hilton Garden Inn Beaufort

3.0 star property
8.4 out of 10, Very good, (1003)
"Professional staff and great area. Will definitely stay here again in the near future. "
The price is ฿3,231
฿3,554 total
includes taxes & fees
14 Sept - 15 Sept
Hilton Garden Inn Beaufort

Best Western Sea Island Inn

2.5 star property
9.4 out of 10, Exceptional, (996)
"Great location."
The price is ฿4,803
฿5,283 total
includes taxes & fees
8 Sept - 9 Sept
Best Western Sea Island Inn

Best Western Plus Bluffton / Hilton Head Hotel

2.5 star property
9.4 out of 10, Exceptional, (115)
"Great place to stay."
The price is ฿4,203
฿4,623 total
includes taxes & fees
7 Sept - 8 Sept
Best Western Plus Bluffton / Hilton Head Hotel

The Emerald Boutique Stays

2.5 star property
9.2 out of 10, Wonderful, (190)
" the place was relaxing and inviting to all my sense and visit in the future"
The price is ฿4,616
฿5,078 total
includes taxes & fees
1 Sept - 2 Sept
The Emerald Boutique Stays

Simple Rewards Inn

2.5 star property
8.6 out of 10, Excellent, (1001)
"Clean, quiet stay and staff are great!"
The price is ฿2,644
฿2,909 total
includes taxes & fees
14 Sept - 15 Sept
Simple Rewards Inn

Quality Inn

2.5 star property
7.6 out of 10, Good, (183)
"It’s was nice and the best breakfast around In my opinion."
The price is ฿2,080
฿2,350 total
includes taxes & fees
21 Sept - 22 Sept
Quality Inn

Hampton Inn Yemassee/Point South

2.5 star property
8.8 out of 10, Excellent, (729)
"Great location with close fast food options. Easy & fast check-in. Room was large, clean, & comfortable. "
The price is ฿3,803
฿4,297 total
includes taxes & fees
23 Sept - 24 Sept
Hampton Inn Yemassee/Point South

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

3.0 star property
8.2 out of 10, Very good, (1002)
"We enjoy staying here when staying in Beaufort. Enjoyed breakfast buffet."
The price is ฿3,228
฿3,622 total
includes taxes & fees
14 Sept - 15 Sept
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

607 Bay Inn Downtown Beaufort

2.5 star property
9.8 out of 10, Exceptional, (68)
"Clean and staff was friendly"
607 Bay Inn Downtown Beaufort

Home2 Suites BY Hilton Beaufort, SC

3.0 star property
9.2 out of 10, Wonderful, (671)
"Amazingly large rooms and equipped with everything! "
The price is ฿3,540
฿3,894 total
includes taxes & fees
8 Sept - 9 Sept
Home2 Suites BY Hilton Beaufort, SC

Circa 1785

4.0 star property
9.6 out of 10, Exceptional, (107)
"Beautiful inn, close enough to walk to the waterfront, but far enough away to be quiet at night. Easy check in, comfortable and spacious rooms. "
The price is ฿4,968
฿5,465 total
includes taxes & fees
31 Aug - 1 Sept
Circa 1785

Oasis Inn

2.5 star property
7.4 out of 10, Good, (590)
"Worth the stay,relaxing atmosphere for me. Had access to shops and restaurants and every other convenient thing,nice stay."
The price is ฿3,486
฿3,835 total
includes taxes & fees
30 Aug - 31 Aug
Oasis Inn

Beach House Resort Hilton Head

4.0 star property
8.8 out of 10, Excellent, (819)
"The location directly on the beach was wonderful! The pool area was very nice! "
The price is ฿4,736
฿6,395 total
includes taxes & fees
14 Sept - 15 Sept
Beach House Resort Hilton Head

Red Roof Inn Yemassee

2.0 star property
7.6 out of 10, Good, (576)
"Overall a great stay "
The price is ฿2,388
฿2,627 total
includes taxes & fees
1 Sept - 2 Sept
Red Roof Inn Yemassee

514 Sunsuite

3.0 star property
The price is ฿4,995
฿11,844 total
includes taxes & fees
9 Sept - 10 Sept
514 Sunsuite

The Inn & Club at Harbour Town

4.0 star property
9.8 out of 10, Exceptional, (203)
"Great hotel! "
The price is ฿12,041
฿13,245 total
includes taxes & fees
1 Sept - 2 Sept
The Inn & Club at Harbour Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Ladys Island

Check out the local area in Ladys Island—home to attractions like Coosaw Island and Cat Island Driving Range.

Photo by Michael Schuier
Open Photo by Michael Schuier

Top Ladys Island Hotel Reviews

More cheap stays in Ladys Island

More cheap stays in Ladys Island

Explore a world of travel with Expedia

Explore a world of travel with Expedia