The Best Hotels Closest to Guana Tolomato Matanzas National Estuarine Research Reserve in Ponte Vedra Beach - 2026 Updated Prices

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Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

A modern cafe with a central island, bar stools, a refrigerated display, and a 'Top It' sign.

A modern hotel reception area with a curved desk, a large digital screen, and a seating area with blue cushions.

A modern office space with a red and blue seating area, a computer desk, and a large window providing a view of the outdoors.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

1. Tru By Hilton St. Augustine I-95

14.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jennifer

฿2,712

฿3,024 total

includes taxes & fees

27 Sept - 28 Sept

A spacious hotel lobby with a reception desk, seating area with sofas, and a large window providing natural light.

A spacious dining area with a long table and multiple chairs, a bar area with shelves of bottles, and a seating area with a sofa and chairs.

A spacious hotel lobby with a modern design, featuring a reception desk, seating area with sofas and chairs, and a large television on the wall.

A hotel with a covered entrance, multiple floors, and a sign indicating "Comfort Suites."

2. Comfort Suites St. Augustine Historic District Area

11.5 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Samuel

฿2,991

฿3,335 total

includes taxes & fees

18 Oct - 19 Oct

A wooden gazebo with a balcony, a staircase, and outdoor seating.

A living room with a brown leather sofa, blue armchairs, a coffee table, and a TV on a wooden cabinet.

A hotel room with two beds, a desk, a TV, and a bathroom.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a large window with curtains.

3. The Bayfront Inn

14.9 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Danielle

฿4,203

฿4,687 total

includes taxes & fees

20 Sept - 21 Sept

A two-story house with a porch, a front door, and a small front yard with plants.

A living room with a large flat-screen TV mounted on a wall, a wooden dresser, a gray sofa, and a hallway leading to another room.

A dining area with a glass table, metal chairs, a brick fireplace, and a chandelier.

A bedroom with a large bed, a ceiling fan, a window with shutters, and a dresser.

4. Carriage Way Inn

14.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Christopher

฿5,161

฿5,754 total

includes taxes & fees

22 Sept - 23 Sept

A waterfront marina with boats docked, a bridge, and a sunset over the water.

A fire feature with a view of a waterfront and a bridge in the background.

A dining table with two chairs, a wine glass, a rose, and a glass of beer.

A poolside area with lounge chairs and a view of the marina and sunset.

5. Marker 8 Hotel & Marina

14.7 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jose

฿4,785

฿5,336 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a marble floor, a reception desk, and a large wall mural.

A modern cafe interior with a central table, counter, and various food and drink dispensers.

A pool area with lounge chairs and a staircase leading to a building.

A hotel lobby with a seating area featuring green armchairs, a round coffee table, and a bar area in the background.

6. Hampton Inn St. Augustine Downtown Historic District

13.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jose

฿3,194

฿3,561 total

includes taxes & fees

12 Oct - 13 Oct

A spacious indoor area with hexagonal tile flooring, multiple seating arrangements including bar stools and tables, ceiling fans, and hanging pendant lights.

A modern meeting room with a large table, six grey chairs, a chandelier, large windows with sheer curtains, and a patterned carpet.

A modern bar area with a central bar, multiple seating options including bar stools and round tables, and a decorative ceiling.

A modern hotel lobby with a seating area, a dining table, and large windows.

7. Hyatt Place St. Augustine/Vilano Beach

12.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Alyssa

฿3,675

฿4,098 total

includes taxes & fees

27 Sept - 28 Sept

An indoor swimming pool with a wooden ceiling, clear pool area, and lounge chairs.

A modern cafe with seating areas, a coffee station, and a view of the outdoors.

A beach with people walking along the shore.

A modern hotel lobby with a reception desk, seating area, and large windows offering views of palm trees.

8. Holiday Inn Express St. Augustine - Vilano Beach by IHG

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Shannon

฿4,811

฿5,766 total

includes taxes & fees

21 Sept - 22 Sept

A modern kitchen with white countertops, a stainless steel sink, a coffee maker, and a window with a view of the outside.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a flat-screen TV, and a dining area with pink chairs.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a coffee maker, and a pink chair.

A living room with a green sofa, a wooden coffee table, and a wall mural depicting a beach scene. There are four framed artworks on the wall and two round stools.

9. Haleys Court Boutique Motel

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

John

฿2,436

฿4,579 total

includes taxes & fees

22 Sept - 23 Sept

A covered porch with wicker furniture and potted plants, overlooking a street with parked cars and palm trees.

A dining room with a large mirror, multiple tables, chairs, and a view of the outside through large windows.

A coffee maker on a table by a window with a view of a beach and a road.

A bedroom with a large bed, wooden headboard, and blue patterned curtains.

10. Bayfront Westcott House St Augustine B&B

14.9 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Kelah Dlynn

฿6,606

฿7,366 total

includes taxes & fees

27 Sept - 28 Sept

An upper front porch with a white floor, black railings, and two rocking chairs.

A covered outdoor seating area with benches and a wooden ceiling.

A two-story building with a dark blue exterior and a white trim, featuring a large window and a flag.

A Zora Suite with a bed, a desk with a plant, a white furry rug, and a painting on the wall.

11. Zora's Sojourn

15 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Daniela

฿3,371

฿4,686 total

includes taxes & fees

21 Sept - 22 Sept

A two-story building with a porch, a 'Vacancy' sign, and a 'Easy Inn Office' sign.

A motel with a sign indicating 'No Vacancy' and an American flag.

A kitchen with white cabinets, a microwave, an oven, a sink, and a refrigerator.

A compact living space with a grey sofa, a small dining table, a white kitchen with a microwave and oven, and a decorative mirror.

12. The Cozy Inn

12.4 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Graciela

฿2,971

฿3,596 total

includes taxes & fees

20 Sept - 21 Sept

A building with a covered porch, outdoor lighting, and greenery.

A bathroom with a wooden vanity, a sink, a mirror, a microwave, and a coffee maker.

A hotel room with two beds, a desk, and a kitchenette.

A two-story building with a white exterior and a brick staircase.

13. Quality Inn St Augustine Historic District Area

11.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Miguel

฿1,881

฿2,097 total

includes taxes & fees

24 Sept - 25 Sept

A waterfront promenade with a white railing, a bench, and a view of a cityscape across the water.

A door leading to a balcony with a view of a calm body of water and a cityscape in the background.

A beachfront motel with multiple rooms, a pool, and a beach view.

A dining table with breakfast items and a view of a waterfront.

14. Edgewater Inn

14.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Beverly

฿3,357

฿3,743 total

includes taxes & fees

20 Sept - 21 Sept

A reception area with leather sofas, a glass coffee table, and a reception desk.

A hotel room with two beds, a small round table, a sofa, and a bathroom visible through an open door.

A building with a blue roof and a sign that reads "Regency Inn & Suites".

A modern living room with a glass coffee table, black leather sofas, and a flat-screen TV mounted on the wall.

15. Regency Inn & Suites

19.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

John

฿1,782

฿1,987 total

includes taxes & fees

20 Sept - 21 Sept

A wooden deck with a metal table and chairs, a yellow railing, and a view of parked cars and palm trees.

A wooden reception desk with a large mirror, glass-fronted cabinets, and framed pictures on the wall.

A neatly made bed with white linens, a vase with red roses, a champagne bucket, and a tray with glasses and a cake on a wooden table.

A two-story yellow building with a balcony, numbered 29, and a red umbrella.

16. Agustin Inn

14.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Yamir

฿3,131

฿3,491 total

includes taxes & fees

27 Sept - 28 Sept

A two-story building with a balcony, decorated with lights and plants.

A bathroom with a vanity, mirror, and three lights above the mirror.

A dining area with round tables and chairs, a wooden cabinet, and framed pictures on the walls.

A narrow brick pathway flanked by metal gates and potted plants, leading to a building with white siding and a window with a wooden frame.

17. 44 Spanish Street Inn - Adults Only

14.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Mildred

฿5,021

฿5,598 total

includes taxes & fees

20 Sept - 21 Sept

A building with a door, a sign, and a Pepsi sign.

A kitchen with granite countertops, a refrigerator, and a coffee machine.

An outdoor seating area with tables and chairs, a covered pavilion, and an American flag.

An outdoor patio area with a grill, seating, and a sign advertising new rooms.

18. Budget Inn St. Augustine

14.7 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Filiz

฿2,131

฿2,376 total

includes taxes & fees

23 Sept - 24 Sept

A hotel with a pool, a covered entrance, and a sign for 'City Express by Marriott.'

A modern hotel room with a wooden floor, a sofa, a small table, a chair, and a TV.

A hotel room with two beds, a TV, and artwork on the wall.

A modern dining area with tables and chairs, a kitchen area with a yellow and white chevron pattern wall, and a counter with various items.

19. City Express By Marriott St. Augustine

12.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

David

฿2,796

฿3,118 total

includes taxes & fees

21 Sept - 22 Sept

A multi-story hotel with a waterfront view, featuring a reflective pool in front.

A spacious lobby with a modern bar area, seating arrangements, and a herringbone-patterned wall.

An outdoor patio with wicker furniture, a grill, and a view of the building's interior.

A coastal hotel with a beach view, a parking lot, and a boardwalk over the water.

20. Homewood Suites by Hilton St. Augustine San Sebastian

14.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Annie

฿3,794

฿4,231 total

includes taxes & fees

23 Sept - 24 Sept

View all properties

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Property	Property class	Guest rating
Tru By Hilton St. Augustine I-95	9.4 Exceptional 445 reviews	View
Comfort Suites St. Augustine Historic District Area	9.2 Wonderful 1,808 reviews	View
The Bayfront Inn	9.4 Exceptional 1,006 reviews	View
Carriage Way Inn	9.8 Exceptional 878 reviews	View
Marker 8 Hotel & Marina	9.6 Exceptional 1,002 reviews	View

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

Quality Inn St Augustine Historic District Area

10/10 Excellent

"Super staff room was clean and bright great location"

The Flagler Inn

10/10 Excellent

"Great place to stay, staff was great. Location was perfect not too far from downtown. Room was very comfortable and clean. Room AC worked very good, breakfast was could’ve been better."

Hyatt Place St. Augustine/Vilano Beach

10/10 Excellent

"Nice staff, clean rooms"

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

8.6/10 (9 reviews)

Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area.

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South Ponte Vedra Beach

Why not spend a lazy afternoon at South Ponte Vedra Beach during your trip to Ponte Vedra Beach?

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Guana River Wildlife Management Area

You can take time to visit Guana River Wildlife Management Area during your travels to Ponte Vedra Beach.

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Water + Stone Gallery

You can browse the exhibits at Water + Stone Gallery, a museum with a storied past, during your travels to St. Augustine. Wander the beautiful beaches and seaside in the area.

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Castle Otttis

8.8/10 (8 reviews)

Castle Otttis is just one of the places to see in St. Augustine, so why not enjoy the other things to explore during your travels? Wander the beautiful beaches and seaside in the area.

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Usina Beach

Why not spend a care-free afternoon at Usina Beach during your travels in Ponte Vedra Beach?

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The Schoolyard

The Schoolyard is just one of the places to see in Nocatee, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around Guana Tolomato Matanzas National Estuarine Research Reserve?

Guana Tolomato Matanzas National Estuarine Research Reserve is located in a family-friendly area of Ponte Vedra Beach known for its interesting historical sites and major shopping area. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Comfort Suites St. Augustine Historic District Area is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. You'll find it 7.1 mi (11.5 km) from Guana Tolomato Matanzas National Estuarine Research Reserve.

How many hotels should I expect to find close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Expedia has 49 hotels and other accommodation options within a mile from Guana Tolomato Matanzas National Estuarine Research Reserve.

If I need to cancel the hotel reservation for my stay near Guana Tolomato Matanzas National Estuarine Research Reserve, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Guana Tolomato Matanzas National Estuarine Research Reserve.

Search Hotels Near Guana Tolomato Matanzas National Estuarine Research Reserve, Ponte Vedra Beach

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Treat yourself

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Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

1. Tru By Hilton St. Augustine I-95

2. Comfort Suites St. Augustine Historic District Area

3. The Bayfront Inn

4. Carriage Way Inn

5. Marker 8 Hotel & Marina

6. Hampton Inn St. Augustine Downtown Historic District

7. Hyatt Place St. Augustine/Vilano Beach

8. Holiday Inn Express St. Augustine - Vilano Beach by IHG

9. Haleys Court Boutique Motel

10. Bayfront Westcott House St Augustine B&B

11. Zora's Sojourn

12. The Cozy Inn

13. Quality Inn St Augustine Historic District Area

14. Edgewater Inn

15. Regency Inn & Suites

16. Agustin Inn

17. 44 Spanish Street Inn - Adults Only

18. Budget Inn St. Augustine

19. City Express By Marriott St. Augustine

20. Homewood Suites by Hilton St. Augustine San Sebastian

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

Quality Inn St Augustine Historic District Area

The Flagler Inn

Hyatt Place St. Augustine/Vilano Beach

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

South Ponte Vedra Beach

Guana River Wildlife Management Area

Water + Stone Gallery

Castle Otttis

Usina Beach

The Schoolyard

Frequently asked questions