Photo by Ruslian

Search Hotels in Greenville Downtown, Greenville

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Greenville Downtown hotels

Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1000)
"I have stayed here several times and it is always clean and comfortable, also the staff is very nice. "
United States
Melissa
The price is ฿3,422
฿3,764 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Place Greenville Downtown

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (423)
"Absolutely one of the best hotels to stay at. "
United States
stephen
The price is ฿9,767
฿11,037 total
includes taxes & fees
14 Jan - 15 Jan 2026
Grand Bohemian Lodge Greenville, Autograph Collection

Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace
2.5 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1001)
"Clean and nice place to stay "
United States
Karina
The price is ฿4,056
฿4,583 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hyatt Regency Greenville

Hyatt Regency Greenville
3.5 star property
Greenville Downtown
8.6 out of 10, Excellent, (1000)
"clean room, very nice hotel, easy access to food / shopping"
United States
chad
The price is ฿4,199
฿4,758 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency Greenville

SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown
2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1007)
"Great spot and beautiful hotel!"
United States
Lisa
The price is ฿3,807
฿4,188 total
includes taxes & fees
1 Jan - 2 Jan 2026
SpringHill Suites by Marriott Greenville Downtown

Holiday Inn Express & Suites Greenville - Downtown by IHG

Holiday Inn Express & Suites Greenville - Downtown by IHG
2.5 star property
Greenville Downtown
8.8 out of 10, Excellent, (1004)
"Great location, very friendly staff, nice room"
United States
Coltin
The price is ฿3,112
฿3,424 total
includes taxes & fees
10 Jan - 11 Jan 2026
Holiday Inn Express & Suites Greenville - Downtown by IHG

Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1000)
"Beautiful hotel. "
United States
Mickey
The price is ฿3,708
฿4,190 total
includes taxes & fees
1 Jan - 2 Jan 2026
Homewood Suites by Hilton Greenville Downtown

AC Hotel By Marriott Greenville

AC Hotel By Marriott Greenville
3.5 star property
Greenville Downtown
9.4 out of 10, Exceptional, (708)
"excellent staff and location. enjoyed our stay!"
United States
JONATHAN
The price is ฿4,728
฿5,201 total
includes taxes & fees
22 Jan - 23 Jan 2026
AC Hotel By Marriott Greenville

The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1003)
"Great historic hotel. Great location and awesome staff."
United States
John
The price is ฿5,257
฿5,783 total
includes taxes & fees
25 Dec - 26 Dec
The Westin Poinsett Greenville

Courtyard by Marriott Greenville Downtown

Courtyard by Marriott Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1006)
"Great location, friendly staff, clean room, overall a nice place to stay. "
United States
Ma Fatima
The price is ฿4,072
฿4,479 total
includes taxes & fees
22 Jan - 23 Jan 2026
Courtyard by Marriott Greenville Downtown

Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1000)
"Super clean! Friendly staff and breakfast was great!"
United States
April
The price is ฿3,420
฿3,762 total
includes taxes & fees
30 Dec - 31 Dec
Home2 Suites by Hilton Greenville Downtown

Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace
3.5 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1000)
"Lovely stay"
United States
Teri
The price is ฿4,311
฿4,742 total
includes taxes & fees
11 Jan - 12 Jan 2026
Embassy Suites by Hilton Greenville Downtown Riverplace

Aloft Greenville Downtown

Aloft Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1000)
"Always a great place to stay. "
United States
Daniel
The price is ฿4,032
฿4,436 total
includes taxes & fees
1 Jan - 2 Jan 2026
Aloft Greenville Downtown

Mint House Greenville - Downtown

Mint House Greenville - Downtown
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (780)
"Spotless wonderful stay"
United States
Tanganica
The price is ฿4,451
฿5,030 total
includes taxes & fees
28 Dec - 29 Dec
Mint House Greenville - Downtown

Pettigru Place Bed & Breakfast

Pettigru Place Bed & Breakfast
3.5 star property
Greenville Downtown
10.0 out of 10, Exceptional, (125)
"Room was great, clean and comfortable. Staff was outstanding. Great breakfast as well. Super place to stay "
United States
Blake
The price is ฿6,159
฿6,775 total
includes taxes & fees
4 Jan - 5 Jan 2026
Pettigru Place Bed & Breakfast

Residence Inn by Marriott Greenville Downtown

Residence Inn by Marriott Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (339)
"Clean rooms, friendly staff, great location and great breakfast choices."
United States
Demetrius
The price is ฿4,733
฿5,206 total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Greenville Downtown

Swamp Rabbit Inn

Swamp Rabbit Inn
3.0 star property
Greenville Downtown
9.0 out of 10, Wonderful, (362)
"Great location and fun place to stay. "
United States
alfred
The price is ฿3,051
฿3,668 total
includes taxes & fees
1 Jan - 2 Jan 2026
Swamp Rabbit Inn

Holiday Inn Express & Suites Greenville S- Piedmont by IHG

Holiday Inn Express & Suites Greenville S- Piedmont by IHG
2.5 star property
10.3 km from Greenville Downtown
9.0 out of 10, Wonderful, (485)
"Nice place to sleep and relax on my way to NC. Clean, good breakfast, very helpful staff!"
United States
Alan Jesus
The price is ฿3,950
฿4,385 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Greenville S- Piedmont by IHG

Comfort Suites Piedmont - Greenville South

Comfort Suites Piedmont - Greenville South
2.5 star property
10.5 km from Greenville Downtown
8.6 out of 10, Excellent, (928)
"Staff was super friendly "
United States
Brittany
The price is ฿3,336
฿3,702 total
includes taxes & fees
13 Jan - 14 Jan 2026
Comfort Suites Piedmont - Greenville South

Best Western Plus Greenville South

Best Western Plus Greenville South
2.5 star property
10.4 km from Greenville Downtown
8.2 out of 10, Very good, (674)
"It was thanksgiving breakfast staff was off which was ok with us. Cause they needed to be with their family also. We had an amazing stay either way we will stay again."
United States
Lea
The price is ฿3,173
฿3,522 total
includes taxes & fees
27 Dec - 28 Dec
Best Western Plus Greenville South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Greenville Downtown

Find the best Greenville Downtown areas for the activities you enjoy most.

Nicholtown

If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.

West End

Visitors to West End like its restaurants and waterfalls, and Bi Lo Center is a sight worth a stop.

Payne-Logan

While Payne-Logan may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Fluor Field at the West End and The Peace Center.

Green Avenue

While there might not be top attractions in Green Avenue, you can explore the larger area and discover places like Fluor Field at the West End and The Peace Center.

Pettigru Street Historic District

Visitors to Pettigru Street Historic District enjoy its restaurants, and if you want to do some exploring, Museum and Library of Confederate History is worth a stop.

Top Greenville Downtown Hotel Reviews

Frequently asked questions

What is Greenville Downtown like?
Travellers love the Greenville Downtown neighbourhood for its stunning river views, array of dining options and major shopping area. Are you looking for Greenville Downtown travel tips? Make sure that you visit The Peace Center and Bon Secours Wellness Arena while you're in the neighbourhood.
Where is the best place to stay in Greenville Downtown?
Based on Expedia customer reviews, Hyatt Place Greenville Downtown is the highest ranked property in Greenville Downtown. This hotel offers a restaurant and an indoor pool. Other top choices in the neighbourhood include Courtyard by Marriott Greenville Downtown and Grand Bohemian Lodge Greenville, Autograph Collection.
How many hotels should I expect to find in the Greenville Downtown area?
Expedia has 94 hotels and other accommodation options in Greenville Downtown to choose from, making this an ideal home base for exploring the greater Greenville area.
If I need to cancel my hotel reservation in Greenville Downtown, will I receive a refund?
Yes, the majority of room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Greenville Downtown.
What is there to do in this Greenville neighbourhood?
The Children's Museum of the Upstate, Greenville Zoo and Shoeless Joe Jackson Museum are fun stops for the whole family while you're in Greenville Downtown. The Peace Center and Bon Secours Wellness Arena are also a couple of places to visit in the neighbourhood. Alchemy Comedy Theater, Piazza Bergamo and Centre Stage are just a few of the places to visit in and around Greenville Downtown. Greenville County Museum of Art and Kilgore Lewis House are also worth a visit when you're out sightseeing in Greenville.