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Our top choices for Federal Medical Center hotels

Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 2.1 km from Federal Medical Center
9.6 out of 10, Exceptional, (547)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is ฿5,424
฿6,245 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hilton Rochester Mayo Clinic Area
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 2.8 km from Federal Medical Center
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is ฿4,020
฿4,628 total
includes taxes & fees
10 Jan - 11 Jan 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 2.3 km from Federal Medical Center
9.2 out of 10, Wonderful, (1008)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is ฿4,589
฿5,283 total
includes taxes & fees
24 Jan - 25 Jan 2026
Hyatt House Rochester/Mayo Clinic Area
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 2.1 km from Federal Medical Center
9.2 out of 10, Wonderful, (168)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is ฿4,986
฿5,740 total
includes taxes & fees
9 Jan - 10 Jan 2026
Broadway Plaza, Trademark Collection by Wyndham
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 2.1 km from Federal Medical Center
8.8 out of 10, Excellent, (894)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is ฿2,532
฿2,915 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 2.2 km from Federal Medical Center
8.8 out of 10, Excellent, (856)
"Yes the workers are amazing "
United States
Luciana
The price is ฿3,367
฿3,876 total
includes taxes & fees
30 Jan - 31 Jan 2026
Hilton Garden Inn Rochester Downtown, MN
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 2.5 km from Federal Medical Center
8.8 out of 10, Excellent, (1003)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is ฿3,561
฿4,099 total
includes taxes & fees
1 Jan - 2 Jan 2026
Brentwood Inn & Suites
Front of property – evening/night
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 2.3 km from Federal Medical Center
8.4 out of 10, Very good, (1850)
"Room was clean staff was excellent! "
United States
Helen
The price is ฿3,925
฿4,518 total
includes taxes & fees
2 Jan - 3 Jan 2026
Kahler Grand Hotel
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest, 2.7 km from Federal Medical Center
8.6 out of 10, Excellent, (1003)
"the breakfast and the friendly check-in staff"
United States
Ella
The price is ฿4,306
฿4,957 total
includes taxes & fees
14 Jan - 15 Jan 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
View from property
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
3.5 star property
Downtown Rochester, 2.2 km from Federal Medical Center
8.4 out of 10, Very good, (527)
"it was a fantastic "
United States
Paul
The price is ฿5,316
฿6,121 total
includes taxes & fees
30 Jan - 31 Jan 2026
Marriott Rochester Mayo Clinic
Terrace/patio
Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 2.6 km from Federal Medical Center
8.4 out of 10, Very good, (200)
"Breakfast great and staff very helpful. "
Canada
John
The price is ฿4,716
฿5,429 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott Rochester Mayo Clinic Area
Room, 2 Queen Beds | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester, 2.5 km from Federal Medical Center
8.0 out of 10, Very good, (1523)
"Clean room, good room service and good breakfast."
United States
Donald
The price is ฿3,806
฿4,382 total
includes taxes & fees
6 Jan - 7 Jan 2026
Kahler Inn and Suites - Mayo Clinic Area
Exterior
Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
3 km from Federal Medical Center
7.2 out of 10, Good, (723)
"The room was very clean and quiet.. coffee at the morning breakfast was very strong.. and not to my liking. "
United States
Frank
The price is ฿1,937
฿2,230 total
includes taxes & fees
11 Jan - 12 Jan 2026
Baymont by Wyndham Rochester Mayo Clinic Area
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 3.4 km from Federal Medical Center
9.4 out of 10, Exceptional, (971)
"The staff was very friendly and the room spotless. "
United States
Judith
The price is ฿3,608
฿4,217 total
includes taxes & fees
2 Jan - 3 Jan 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 3.4 km from Federal Medical Center
9.4 out of 10, Exceptional, (425)
"This was an amazing find in Rochester. Looking forward to staying here again. "
United States
Kellie
The price is ฿4,530
฿5,278 total
includes taxes & fees
18 Jan - 19 Jan 2026
Staybridge Suites Rochester - Mayo Clinic Area by IHG
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 4.1 km from Federal Medical Center
9.6 out of 10, Exceptional, (680)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is ฿3,102
฿3,571 total
includes taxes & fees
18 Jan - 19 Jan 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Terrace/patio
The Berkman

The Berkman

The Berkman
3.0 star property
Folwell, 3.8 km from Federal Medical Center
9.6 out of 10, Exceptional, (373)
"Staff was great, as was the room."
United States
Scott
The price is ฿5,295
฿6,157 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Berkman
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
4.2 km from Federal Medical Center
9.6 out of 10, Exceptional, (887)
"Great stay,clean and friendly"
United States
Janet
The price is ฿3,756
฿4,324 total
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
BBQ/picnic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
4.2 km from Federal Medical Center
9.6 out of 10, Exceptional, (256)
"Rooms were clean staff was courteous. "
United States
Michael
The price is ฿4,399
฿5,065 total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Rochester Mayo Clinic Area South
Exterior
Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
3.6 km from Federal Medical Center
9.2 out of 10, Wonderful, (455)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is ฿3,051
฿3,513 total
includes taxes & fees
6 Jan - 7 Jan 2026
Candlewood Suites Rochester Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Federal Medical Center Hotel Reviews

Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"Room was great. They put us near their pool which was requested. Food was great at their restaurant."
Frederik 1-night trip
Posted 4 days ago
Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"It was an amazing stay. Shuttle to the hospital saved parking headaches. "
Tricia 2-night trip
Posted 2 weeks ago
AmericInn by Wyndham Rochester Near Mayo Clinic

Hotels near other Federal Medical Center attractions

Quarry Hill Nature Center

Explore the great outdoors at Quarry Hill Nature Center, a lovely green space in Rochester. You can attend a sporting event while in the area.
See properties

Regional Sports Center

4.4/5 (19 reviews)
Catch an event at Regional Sports Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Frequently asked questions

What's the area like around Federal Medical Center?
Federal Medical Center is located in Rochester. Travellers love the area for its array of dining options, sporting events and major shopping area. If you're looking for a convenient place to stay, take a look at the 25 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Federal Medical Center?
Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. It's located 1.5 mi (2.3 km) from Federal Medical Center. Other good choices within a few miles include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find close to Federal Medical Center?
Expedia has 25 hotels and other accommodation options within a mile from Federal Medical Center.
If I need to cancel the hotel reservation for my stay near Federal Medical Center, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view top deals close to Federal Medical Center.
What can I see and do near Federal Medical Center?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Sights like Assisi Heights and Plummer House highlight some of the local culture. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.