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Check prices for these dates

Tonight
4 Mar - 5 Mar
Tomorrow
5 Mar - 6 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for Downtown hotels

Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (683 reviews)
"Everting was good"
United States
Susan
The price is ฿2,460
฿2,898 total
includes taxes & fees
15 Mar - 16 Mar
Quality Inn Seneca Clemson Area US-123
Property amenity

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (598 reviews)
"Clean, quiet, comfortable stay- staff is always friendly and helpful!"
United States
Lori
The price is ฿3,254
฿3,612 total
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Economy Room, 1 King Bed, Non Smoking | Rollaway beds, free WiFi, bed sheets

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (176 reviews)
"Older hotel with great staff. It was safe and provided a great place for a stop over on the way to TN. I would definitely stay here again. "
United States
Laura
The price is ฿2,282
฿2,544 total
includes taxes & fees
3 Apr - 4 Apr
Rodeway Inn & Suites Walhalla
Free daily on-the-go breakfast

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (729 reviews)
"Very nice and helpful at the fronte desk. Nice room and very comfortable bed"
United States
Crystal
The price is ฿2,282
฿2,511 total
includes taxes & fees
7 Mar - 8 Mar
Days Inn by Wyndham Seneca / Clemson Area
Hallway

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (801 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is ฿4,707
฿5,225 total
includes taxes & fees
8 Mar - 9 Mar
The Inn at Patrick Square
Front of property

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (83 reviews)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
Liberty Hall Bed and Breakfast
Lobby

Americas Best Value Inn Anderson, SC

Americas Best Value Inn Anderson, SC
2.0 star property
27.9 km from Downtown
6.0 out of 10, (158 reviews)
"Nice little motel with friendly owners. Beds were a little too firm and breakfast a bit lacking, but for the price, it was fine. We enjoyed our stay. "
United States
Heather
The price is ฿2,180
฿2,420 total
includes taxes & fees
6 Mar - 7 Mar
Americas Best Value Inn Anderson, SC
Free breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very good, (1,009 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
The price is ฿2,881
฿3,197 total
includes taxes & fees
8 Mar - 9 Mar
Best Western Plus Clemson Hotel & Conference Center
Hallway

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (390 reviews)
"Room was clean and staff was very friendly."
United States
clay
The price is ฿4,142
฿4,921 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Lavonia
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (210 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
The price is ฿3,949
฿4,344 total
includes taxes & fees
9 Mar - 10 Mar
Fairfield Inn & Suites Seneca Clemson Univ Area
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.2 out of 10, Very good, (1,001 reviews)
"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "
United States
Delaney
The price is ฿3,196
฿3,548 total
includes taxes & fees
11 Mar - 12 Mar
Comfort Inn & Suites Clemson - University Area
Golf

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (980 reviews)
"Everything was very nice "
United States
Paige
The price is ฿4,707
฿5,225 total
includes taxes & fees
9 Mar - 10 Mar
Clemson University's James F. Martin Inn
Lobby

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
29.6 km from Downtown
7.0 out of 10, Good, (900 reviews)
"Bueno was "
Mexico
Alejandro
The price is ฿1,702
฿1,890 total
includes taxes & fees
29 Mar - 30 Mar
Quality Inn Clemson near University
Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
7.8 out of 10, Good, (1,006 reviews)
"The room was spotless, the property well kept, the staff was kind and helpful and the location was great! "
United States
Kayla
The price is ฿1,987
฿2,206 total
includes taxes & fees
8 Mar - 9 Mar
Days Inn by Wyndham Anderson
Property amenity

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
3.0 star property
25.1 km from Downtown
9.8 out of 10, Exceptional, (96 reviews)
"fabulous stay, great service and staff, excellent price, lovely amenities. "
United States
Corrina
The price is ฿4,517
฿5,014 total
includes taxes & fees
15 Mar - 16 Mar
Residence Inn by Marriott Anderson Clemson
Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is ฿3,443
฿4,274 total
includes taxes & fees
8 Mar - 9 Mar
Lakeside Lodge Clemson
Lobby

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
24.8 km from Downtown
8.2 out of 10, Very good, (1,000 reviews)
"Room was clean, front desk people were very nice. "
United States
Caressa
The price is ฿2,525
฿2,803 total
includes taxes & fees
8 Mar - 9 Mar
Microtel Inn & Suites by Wyndham Anderson/Clemson
Exterior

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (958 reviews)
"Nice facility "
United States
Rishandrea
The price is ฿3,885
฿4,313 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express & Suites Clemson by IHG
Snack bar

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
25 km from Downtown
8.8 out of 10, Excellent, (413 reviews)
"EXCELLENT hotel and staff"
United States
Douglas
The price is ฿3,586
฿3,980 total
includes taxes & fees
3 Apr - 4 Apr
Hampton Inn Anderson
View from property

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (63 reviews)
"Excellent stay."
United States
Beonca
The price is ฿2,180
฿3,788 total
includes taxes & fees
19 Mar - 20 Mar
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Female Kayaker on Lake Keowee at Sunset

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Seneca City Hall and Oconee County Library Seneca Branch.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Seneca City Hall and Oconee County Library Seneca Branch are some notable places to visit nearby.

Top Downtown Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"Clean room, courtesy of staff, safety"
Nancy 2-night trip
Posted 4 days ago
Best Western Plus Clemson Hotel & Conference Center

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels will I be able to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodation options in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Seneca Historic District, Oconee County Library Seneca Branch and Seneca City Hall are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Wyndham Plaza or Cross Creek Plantation Golf.