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Top 10 Defiance hotels and places to stay

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
7.0 out of 10, Good, (1004)
"The check in was super easy, there was a lady being trained, and they were both so nice! It was super fast, in the selection for the continental breakfast was good!! The area felt good.I would definitely stay here again!! Hotel stuff was super friendly :)"
The price is ฿1,811
฿2,109 total
includes taxes & fees
16 Sept - 17 Sept
Super 8 by Wyndham Eureka/Six Flags Nearby

Super 8 by Wyndham St. Clair MO

2.0 star property
7.2 out of 10, Good, (899)
"Nice location amd staff were very nice would go there again!"
The price is ฿2,389
฿2,615 total
includes taxes & fees
1 Sept - 2 Sept
Super 8 by Wyndham St. Clair MO

Drury Plaza Hotel St. Louis Chesterfield

3.0 star property
9.6 out of 10, Exceptional, (1013)
"Great place to stay! "
The price is ฿4,203
฿4,875 total
includes taxes & fees
3 Sept - 4 Sept
Drury Plaza Hotel St. Louis Chesterfield

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
8.2 out of 10, Very good, (1012)
"Good hotel! "
The price is ฿2,721
฿3,143 total
includes taxes & fees
31 Aug - 1 Sept
Wingate by Wyndham St. Louis/Fenton Route 66

Comfort Inn St. Louis Airport

3.0 star property
8.4 out of 10, Very good, (896)
"Good experience during our stay. "
The price is ฿2,785
฿3,334 total
includes taxes & fees
29 Sept - 30 Sept
Comfort Inn St. Louis Airport

WoodSpring Suites St Peters-OFallon

2.5 star property
The price is ฿2,910
฿3,345 total
includes taxes & fees
29 Sept - 30 Sept
WoodSpring Suites St Peters-OFallon

Holiday Inn Express & Suites St Peters by IHG

2.5 star property
9.2 out of 10, Wonderful, (343)
"Very nice place. Clean... quiet and very friendly staff!! We will definitely stay here again!!"
The price is ฿3,007
฿3,648 total
includes taxes & fees
28 Sept - 29 Sept
Holiday Inn Express & Suites St Peters by IHG

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
7.6 out of 10, Good, (1003)
"And nice hotel at a nice price "
The price is ฿2,774
฿3,272 total
includes taxes & fees
29 Sept - 30 Sept
Comfort Inn & Suites St. Louis - O'Fallon

Best Western Plus St. Louis West-Westport

2.5 star property
8.0 out of 10, Very good, (1014)
"I STAY HERE ALOT ALWAYS A GOOD STAY"
The price is ฿2,881
฿3,342 total
includes taxes & fees
7 Sept - 8 Sept
Best Western Plus St. Louis West-Westport

Super 8 by Wyndham Warrenton

2.0 star property
7.4 out of 10, Good, (584)
"Staff was extremely accommodating and friendly."
The price is ฿2,309
฿2,643 total
includes taxes & fees
7 Sept - 8 Sept
Super 8 by Wyndham Warrenton

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (1006)
"Price and location is excellent "
The price is ฿2,034
฿2,337 total
includes taxes & fees
4 Sept - 5 Sept
Relax Inn Saint Charles

Baymont by Wyndham Warrenton

2.5 star property
7.4 out of 10, Good, (992)
"Very nice accommodations!"
The price is ฿2,910
฿3,331 total
includes taxes & fees
31 Aug - 1 Sept
Baymont by Wyndham Warrenton

Best Western Plus The Charles Hotel

3.0 star property
8.0 out of 10, Very good, (1008)
"I enjoyed my stay the food was good!"
The price is ฿2,858
฿3,314 total
includes taxes & fees
3 Sept - 4 Sept
Best Western Plus The Charles Hotel

La Quinta Inn & Suites by Wyndham St. Louis Westport

3.0 star property
7.2 out of 10, Good, (1042)
"Great stay"
The price is ฿2,794
฿3,240 total
includes taxes & fees
31 Aug - 1 Sept
La Quinta Inn & Suites by Wyndham St. Louis Westport

Economy Inn Wentzville

2.0 star property
6.4 out of 10, (453)
"Best value around this location. Not going to be as nice as holiday Inn , but way better than most budget friendly places."
The price is ฿2,263
฿2,568 total
includes taxes & fees
31 Aug - 1 Sept
Economy Inn Wentzville

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.4 out of 10, Very good, (1009)
"Very good hotel for the price"
The price is ฿2,881
฿3,328 total
includes taxes & fees
2 Sept - 3 Sept
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Extended Stay America Suites St Louis Westport Central

2.5 star property
7.4 out of 10, Good, (987)
"Good place to stay."
The price is ฿2,789
฿3,234 total
includes taxes & fees
15 Sept - 16 Sept
Extended Stay America Suites St Louis Westport Central

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

3.0 star property
9.0 out of 10, Wonderful, (1003)
"Great hotel, very clean"
The price is ฿3,271
฿3,794 total
includes taxes & fees
7 Sept - 8 Sept
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites St Louis Westport

2.5 star property
9.2 out of 10, Wonderful, (789)
"Great place to stay. Friendly staff. Spacious room and hearty yummy breakfast. "
The price is ฿3,949
฿4,580 total
includes taxes & fees
4 Sept - 5 Sept
Fairfield Inn & Suites St Louis Westport

Hilton Garden Inn St. Louis/O'Fallon MO

3.0 star property
8.8 out of 10, Excellent, (695)
"Nice location, with a couple restaurants nearby. Quiet, clean, nice beds/pillows."
The price is ฿4,628
฿5,487 total
includes taxes & fees
5 Sept - 6 Sept
Hilton Garden Inn St. Louis/O'Fallon MO
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Accommodation near Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

More cheap stays in Defiance

More cheap stays in Defiance

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Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West. See all available top hotels, or vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?
How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 17 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.