
Find hotels in Byron, MN from ฿1,989
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Byron
Family friendly
Check prices for these dates
Our top choices for Byron hotels

Americas Best Value Inn & Suites Spring Valley
Americas Best Value Inn & Suites Spring ValleySpring Valley
8.2 out of 10, Very good, (442 reviews)
The price is ฿2,495
฿2,754 total
includes taxes & fees
3 May - 4 May

America's Stay Inn Stewartville
America's Stay Inn StewartvilleStewartville
8.0 out of 10, Very good, (432 reviews)
The price is ฿1,929
฿2,071 total
includes taxes & fees
27 Apr - 28 Apr

Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo ClinicRochester
8.8 out of 10, Excellent, (1,002 reviews)
The price is ฿1,976
฿2,275 total
includes taxes & fees
17 May - 18 May

AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.2 out of 10, Very good, (1,260 reviews)
The price is ฿2,451
฿2,821 total
includes taxes & fees
19 Apr - 20 Apr

Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,002 reviews)
The price is ฿2,947
฿3,393 total
includes taxes & fees
17 May - 18 May

Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.4 out of 10, Exceptional, (439 reviews)
The price is ฿2,623
฿3,020 total
includes taxes & fees
3 May - 4 May

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.2 out of 10, Good, (1,042 reviews)
The price is ฿2,278
฿2,622 total
includes taxes & fees
17 May - 18 May

Birch Hill Suite Rochester – Med City
Birch Hill Suite Rochester – Med CityRochester
7.6 out of 10, Good, (30 reviews)
The price is ฿1,618
฿1,862 total
includes taxes & fees
19 Apr - 20 Apr

Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-NorthRochester
9.2 out of 10, Wonderful, (1,000 reviews)
The price is ฿3,646
฿4,198 total
includes taxes & fees
10 May - 11 May

Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (961 reviews)
The price is ฿2,199
฿2,531 total
includes taxes & fees
17 May - 18 May

Quality Inn near Medical Center
Quality Inn near Medical CenterRochester
7.8 out of 10, Good, (868 reviews)
The price is ฿1,903
฿2,191 total
includes taxes & fees
27 Apr - 28 Apr

Sleep Inn & Suites West-Near Medical Center
Sleep Inn & Suites West-Near Medical CenterRochester
9.0 out of 10, Wonderful, (622 reviews)
The price is ฿2,878
฿3,314 total
includes taxes & fees
9 May - 10 May

Americas Best Value Inn Zumbrota
Americas Best Value Inn ZumbrotaZumbrota
7.2 out of 10, Good, (520 reviews)
The price is ฿2,016
฿2,164 total
includes taxes & fees
20 Apr - 21 Apr

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sRochester
8.2 out of 10, Very good, (884 reviews)
The price is ฿3,009
฿3,464 total
includes taxes & fees
13 May - 14 May

Super 8 by Wyndham Rochester Mayo Clinic Area
Super 8 by Wyndham Rochester Mayo Clinic AreaRochester
7.8 out of 10, Good, (1,001 reviews)
The price is ฿1,659
฿1,910 total
includes taxes & fees
26 Apr - 27 Apr

Country Inn & Suites by Radisson, Rochester, MN
Country Inn & Suites by Radisson, Rochester, MNRochester
7.4 out of 10, Good, (1,000 reviews)
The price is ฿2,132
฿2,454 total
includes taxes & fees
19 Apr - 20 Apr

Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic AreaRochester
7.2 out of 10, Good, (763 reviews)
The price is ฿1,903
฿2,191 total
includes taxes & fees
22 Apr - 23 Apr

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Microtel Inn & Suites by Wyndham Rochester North Mayo ClinicRochester
8.0 out of 10, Very good, (1,000 reviews)
The price is ฿2,121
฿2,442 total
includes taxes & fees
19 Apr - 20 Apr

Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ฿3,164
฿3,642 total
includes taxes & fees
17 May - 18 May

Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical CenterRochester
9.0 out of 10, Wonderful, (593 reviews)
The price is ฿2,998
฿3,452 total
includes taxes & fees
26 Apr - 27 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Byron attractions
Top Byron Hotel Reviews

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
8/10 Good
More cheap stays in Byron

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
The price is ฿2,419 per night from 20 Apr to 21 Apr
฿2,419
฿2,784 total
20 Apr - 21 Apr
includes taxes & fees
7.8/10 Good! (1,011 reviews)









































































