Byron Holiday Rentals, Minnesota: Private House Rentals

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Our top choices for Byron hotels

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Jon

฿3,695

฿4,254 total

includes taxes & fees

18 Sept - 19 Sept

An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

A Staybridge Suites hotel with a stone facade, multiple windows, and a signboard.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a pool capacity sign.

A Staybridge Suites hotel with a stone facade, a covered entrance, and multiple windows.

2. Staybridge Suites Rochester - Commerce Dr NW by IHG

Rochester

Tamra

฿4,205

฿4,841 total

includes taxes & fees

5 Sept - 6 Sept

A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.

A swimming pool with a lifeguard sign, tiled walls, and a clear blue pool.

A hotel reception area with a reception desk, a waiting area with a sofa, and a clear view of the lobby.

A hotel dining area with multiple tables and chairs, a coffee station, and a seating area with sofas.

3. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Kutzky Park

Janet

฿3,576

฿4,117 total

includes taxes & fees

4 Sept - 5 Sept

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern lounge area with a sofa, chairs, and tables.

A modern restaurant with a counter, seating area, and a TV screen.

4. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

Vickie

฿4,046

฿4,657 total

includes taxes & fees

5 Sept - 6 Sept

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

5. Hampton Inn Rochester-South

Rochester

Lynne

฿3,367

฿3,876 total

includes taxes & fees

7 Sept - 8 Sept

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A modern kitchen with granite countertops, a built-in microwave, and a sink. There are two wooden chairs and a small table.

A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.

A hotel room with a kitchen area, a bed, a TV, and a seating area.

6. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Rochester

Margita

฿3,271

฿3,766 total

includes taxes & fees

20 Sept - 21 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern lounge area with seating, a fireplace, and a bar area.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

7. Residence Inn by Marriott Rochester Mayo Clinic Area South

Rochester

Richard

฿4,536

฿5,222 total

includes taxes & fees

11 Sept - 12 Sept

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

A modern bar area with seating and a counter.

8. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Mary Jo

฿4,768

฿5,489 total

includes taxes & fees

18 Sept - 19 Sept

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A gym with treadmills, elliptical machines, and a stationary bike.

9. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Deborah

฿2,747

฿3,162 total

includes taxes & fees

30 Sept - 1 Oct

A spacious lobby with a reception desk, sofas, and a coffee table.

An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

A hotel room with a large bed, a sofa, a TV, and a desk.

10. Sleep Inn & Suites West-Near Medical Center

Rochester

Kaitlin

฿2,750

฿3,166 total

includes taxes & fees

20 Sept - 21 Sept

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A conference room with a long table, multiple chairs, and decorative wall art.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

11. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park

MATTHEW

฿3,743

฿4,309 total

includes taxes & fees

4 Sept - 5 Sept

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A hotel with a covered entrance, multiple floors, and a parking lot.

A small, well-organized pantry with shelves stocked with snacks and beverages.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

12. Spark by Hilton Rochester South

Rochester

Helena

฿2,552

฿2,938 total

includes taxes & fees

5 Sept - 6 Sept

A modern hotel lobby with a reception desk, seating area, and a dining space.

A hotel room with a bed, desk, chair, and a bathroom.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

A Holiday Inn Express building with a stone facade and illuminated signage.

13. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Stephanie

฿3,477

฿4,003 total

includes taxes & fees

3 Sept - 4 Sept

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.

A spacious lobby with a central seating area, a reception desk, and a fireplace.

14. Comfort Inn & Suites West - Medical Center

Rochester

Gary

฿2,803

฿3,226 total

includes taxes & fees

27 Sept - 28 Sept

A modern dining area with high tables, chairs, and pendant lighting.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

15. Hampton Inn & Suites Rochester-North

Rochester

Albert

฿3,231

฿3,720 total

includes taxes & fees

5 Sept - 6 Sept

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A reception area with a reception desk, two armchairs, a clock, and a framed artwork on the wall.

A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.

A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

16. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Rochester

Siddhartha

฿2,308

฿2,657 total

includes taxes & fees

1 Sept - 2 Sept

An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.

A hotel reception area with a coffee station, seating area, and a fireplace.

A hotel reception area with a red 'Hello' sign, a reception desk, a coffee station, and a fireplace.

A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.

17. TownePlace Suites by Marriott Rochester

Rochester

Larry

฿3,245

฿3,736 total

includes taxes & fees

6 Sept - 7 Sept

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

An indoor swimming pool with a slide, seating areas, and a lifeguard station.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.

18. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Jason

฿2,505

฿2,884 total

includes taxes & fees

6 Sept - 7 Sept

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A garden with a water feature, rocks, and yellow umbrellas.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

19. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Sarah

฿3,781

฿4,353 total

includes taxes & fees

5 Sept - 6 Sept

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A bar with wooden stools and a neon sign.

A hotel room with two beds, a desk, a chair, and a mirror.

An indoor swimming pool with a slide, seating area, and a large frog statue.

20. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

Cathy

฿2,580

฿2,970 total

includes taxes & fees

6 Sept - 7 Sept

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Stay near popular Byron attractions

Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the top-notch restaurants or cosy cafes in this walkable area.

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Salem Glen Winery

You can enjoy a tasting or tour at Salem Glen Winery during your travels to Byron. Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Salem Town Hall

After visiting Salem Town Hall, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Cheery Meadows Center

You can do some window-shopping at Cheery Meadows Center during your trip to Byron. Amble around the area's parks or experience its art scene.

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Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

See properties

Valley View Park

Valley View Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Top Byron Hotel Reviews

Brentwood Inn & Suites

10/10 Excellent

"My room was very clean, the staff were friendly and helpful, and the room rate for two queen beds was very reasonable."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great property. Free breakfast, happy hour a few days, huge lobby and patio are. Convenient shuttle to Mayo Clinic. Fully stocked kitchens, coffee, and dishwasher. Laundry on site if needed."

Aspen Select

10/10 Excellent

"Construction in the area is crazy, but if you are looking for a good price near the Mayo Clinic then this is your hotel. The sister property was almost 3x the price. Still has good access during Mayo construction. Directly across from Saint Mary’s"

Kahler Grand Hotel

8/10 Good

"Toilets were too low for seniors….put higher toilets in. It is ridicules to have to sit almost of the floor, especially in room 562!!! Otherwise every thing was wonderful!!"

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"This property has a good location and since it’s newer, that’s an added bonus. They have a complimentary, elevated breakfast which is great."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The hotel was nice and clean, staff were very pleasant, breakfast was a big tasty buffet. The only complaint was the parking garage was very little and barely fit my mid size SUV because of how low the ceiling was, but there is another garage next to the hotel that was actually cheaper. Also, being on the side where all the construction was going on, but I get it they had to start super early because of the heat. Most importantly though it was with walking distance from all of my Mayo appts and several restaurants."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"

More cheap stays in Byron

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN

฿1,801

฿2,074 total

6 Sept - 7 Sept

includes taxes & fees

7.8/10 Good! (1,002 reviews)

Quality Inn near Medical Center

5708 Bandel Road NW Rochester MN

฿2,083

฿2,398 total

20 Sept - 21 Sept

includes taxes & fees

7.8/10 Good! (950 reviews)

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

฿2,503

฿2,882 total

31 Aug - 1 Sept

includes taxes & fees

8/10 Very good! (1,007 reviews)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

฿3,271

฿3,766 total

20 Sept - 21 Sept

includes taxes & fees

Hampton Inn Rochester-South

1755 S Broadway Rochester MN

฿3,367

฿3,876 total

7 Sept - 8 Sept

includes taxes & fees

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

฿4,139

฿4,765 total

3 Sept - 4 Sept

includes taxes & fees

8.8/10 Excellent! (1,002 reviews)

Frequently asked questions

Where is the best place to stay in Byron?

Located 9 mi (14.4 km) from the heart of Byron, Kahler Grand Hotel is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Byron.

If I need to cancel my hotel reservation in Byron, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.

How is it to stay in Byron?

Visitors can enjoy all that Byron has to offer, including the zoo, golf courses and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 3 hotels and other accommodation options to choose from. Find out more about Byron.

What should I see while I'm in Byron?

Favourite places to visit include Links of Byron Mini Golf, Cheery Meadows Center and High Point Shopping Center. A couple of additional sights to add to your itinerary are Byron Town Square and Somerby Golf Club. Take a look at what more there is to see and do in Expedia's Byron guide.

What's the seasonal weather in Byron?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

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Book Hotels in Byron on Expedia.com

Find hotels in Byron, MN from ฿1,886

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Byron

Check prices for these dates

Filter by

Star rating

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Our top choices for Byron hotels

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

2. Staybridge Suites Rochester - Commerce Dr NW by IHG

3. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

4. Home2 Suites by Hilton Rochester Mayo Clinic Area

5. Hampton Inn Rochester-South

6. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

7. Residence Inn by Marriott Rochester Mayo Clinic Area South

8. Hyatt House Rochester/Mayo Clinic Area

9. Comfort Inn & Suites Rochester South Mayo Clinic

10. Sleep Inn & Suites West-Near Medical Center

11. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

12. Spark by Hilton Rochester South

13. Holiday Inn Express Rochester South - Mayo Area by IHG

14. Comfort Inn & Suites West - Medical Center

15. Hampton Inn & Suites Rochester-North

16. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

17. TownePlace Suites by Marriott Rochester

18. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

19. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

20. AmericInn by Wyndham Rochester Near Mayo Clinic

Stay near popular Byron attractions

Somerby Park

Oxbow Park

Salem Glen Winery

East Brookfield Park

Salem Town Hall

Cheery Meadows Center

Somerby Golf Club

Valley View Park

Top Byron Hotel Reviews

Brentwood Inn & Suites

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Aspen Select

Kahler Grand Hotel

Hyatt House Rochester/Mayo Clinic Area

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kahler Inn and Suites - Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

More cheap stays in Byron

Super 8 by Wyndham Rochester Mayo Clinic Area

Quality Inn near Medical Center

Med City Inn & Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hampton Inn Rochester-South

Brentwood Inn & Suites

Frequently asked questions

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