Search Gay-Friendly Hotels in Uptown - Upper Duval

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Check prices for these dates

Tonight
12 Nov - 13 Nov
Tomorrow
13 Nov - 14 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Our top choices for Uptown - Upper Duval LGBT-friendly hotels

A two-story building with a white picket fence, palm trees, and a sign that reads 'DUVAL GARDENS.'

1. Duval Gardens - Adults Only

Duval Gardens - Adults Only
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (925 reviews)
"Great rooms and staff, the breakfast is amazing "
United States
JoAnn
The price is ฿4,839
฿6,773 total
includes taxes & fees
8 Dec - 9 Dec
Duval Gardens - Adults Only
A beach with a wooden pier, palm trees, and beach umbrellas.

2. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1,069 reviews)
"Clean room,staff,beach view,bar"
United States
Andrzej
The price is ฿7,867
฿11,130 total
includes taxes & fees
19 Nov - 20 Nov
The Reach Key West, Curio Collection by Hilton
A tropical outdoor area with palm trees, hanging plants, and string lights.

3. Douglas House - Adults Only

Douglas House - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (591 reviews)
"Clean place, courteous staff, great location"
United States
Sandra
The price is ฿6,533
฿9,429 total
includes taxes & fees
17 Nov - 18 Nov
Douglas House - Adults Only
A deck with sun loungers and a railing overlooking the sea.

4. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (3,660 reviews)
"Beautiful hotel, loved our stay"
United States
Damian
The price is ฿7,125
฿10,599 total
includes taxes & fees
30 Nov - 1 Dec
Southernmost Beach Resort and Guesthouses
A pool area with lounge chairs and a table, surrounded by palm trees.

5. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,007 reviews)
"Fantastic property. Love staying here 💗"
United States
Jessica
The price is ฿8,492
฿9,553 total
includes taxes & fees
1 Dec - 2 Dec
Orchid Key Inn - Adults Only
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.

6. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very good, (1,023 reviews)
"Great place"
United States
Nguyen
The price is ฿8,047
฿11,332 total
includes taxes & fees
23 Nov - 24 Nov
Casa Marina Key West, Curio Collection by Hilton
A swimming pool with water splashing, surrounded by palm trees and a building in the background.

7. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
3.5 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,040 reviews)
"Very central location"
United States
TODD
The price is ฿5,113
฿8,022 total
includes taxes & fees
2 Dec - 3 Dec
Silver Palms Inn & Historic Homes
A room with a door featuring horizontal blinds, a visible outdoor view through the window, and a patterned carpet.

8. Alexander Palms Court

Alexander Palms Court
2.5 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,007 reviews)
"We love staying at Alexander’s!!!"
United States
Brenda
The price is ฿5,744
฿6,463 total
includes taxes & fees
1 Dec - 2 Dec
Alexander Palms Court
A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

9. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,002 reviews)
"Great spot for a visit to Key West, staff was very helpful and well located for a walk down Duval St."
United States
Ryan
The price is ฿6,138
฿7,746 total
includes taxes & fees
1 Dec - 2 Dec
The Grand Guesthouse
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with a white facade.

10. Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns
3.5 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,000 reviews)
"Staff was amazing, room was spotless, beautiful property, quiet, and convenient"
United States
Elizabeth
The price is ฿6,754
฿9,308 total
includes taxes & fees
30 Nov - 1 Dec
Lighthouse Hotel - Key West Historic Inns
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Uptown - Upper Duval

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A two-story building with a white picket fence, palm trees, and a sign that reads 'DUVAL GARDENS.'
Duval Gardens - Adults Only
4.0 star property
9.2
Wonderful
925 reviews
View
A beach with a wooden pier, palm trees, and beach umbrellas.
The Reach Key West, Curio Collection by Hilton
4.0 star property
8.6
Excellent
1,069 reviews
View
A tropical outdoor area with palm trees, hanging plants, and string lights.
Douglas House - Adults Only
3.5 star property
9.8
Exceptional
591 reviews
View
A deck with sun loungers and a railing overlooking the sea.
Southernmost Beach Resort and Guesthouses
4.0 star property
8.6
Excellent
3,660 reviews
View
A pool area with lounge chairs and a table, surrounded by palm trees.
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,007 reviews
View

Top Uptown - Upper Duval Hotel Reviews

A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Old Town Key West

10/10 Excellent

Everything was great
United Kingdom
John
Reviewed July 15, 2026
Almond Tree Inn Hotel - Adults Only

Frequently Asked Questions

How do I find LGBTQ-friendly accommodation in Uptown - Upper Duval?

Whether you are travelling with your partner or flying solo, you'll find Uptown - Upper Duval hotels that are members of the International Gay & Lesbian Travel Association on Expedia. Discover the people, places and traditions found only in Uptown - Upper Duval.

What's the best LGBTQ-friendly accommodation in Uptown - Upper Duval?

Southernmost Beach Resort and Guesthouses is a top LGBTQ-friendly hotel, and features 3 outdoor pools and pillowtop beds. The Reach Key West, Curio Collection by Hilton and Douglas House - Adults Only are two other good options for your stay.

How many gay-friendly accommodation options are there in Uptown - Upper Duval?

There are currently 6 gay-friendly hotels in Uptown - Upper Duval.

What should I see while I'm in Uptown - Upper Duval?

During your trip, get out and enjoy everything Uptown - Upper Duval has to offer. You and your travelling companions may want to visit Duval Street and Florida Keys Beaches. While you're here, create some great memories of your trip with stops at Key West Butterfly and Nature Conservatory, South Beach and Southernmost Point.

What is a gay-friendly hotel in Uptown - Upper Duval?

LGBTQ-friendly hotels welcome all travellers who identify as LGBTQIA+. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In Uptown - Upper Duval, hotels affiliated with IGLTA prioritise a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.

What can I expect from an LGBTQ-friendly Uptown - Upper Duval hotel?

Stay at a gay-friendly hotel in Uptown - Upper Duval and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer concierge services that provide information about nearby LGBTQ restaurants and local events.