St. Marys Holiday Rentals, Saint Charles: Private House Rentals

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in St. Marys

Pet friendly

Apartment

Pool

Hot tub

Family friendly

Waterpark

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for St. Marys hotels

A sunroom with a glass ceiling, wicker furniture, and potted plants.

An indoor swimming pool with clear glass walls, white lounge chairs, and a tiled floor.

A spacious lobby with a high ceiling, a seating area with sofas and ottomans, a reception desk, and a staircase to an upper level.

A hotel room with a bed, a blue armchair, a desk, and a nightstand.

1. Baymont by Wyndham Des Moines Airport

Southwestern Hills

Michael

฿3,244

฿3,634 total

includes taxes & fees

23 Sept - 24 Sept

A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

A reception desk with a wooden finish, a sign reading "welcome to Des Moines," and a framed picture above the door.

A hotel room with a large bed, a desk, a television, and a window with a view of trees.

A vending machine with snacks and beverages, a shelf with various snack brands, and a sign indicating 'IA TREATS'.

2. Hampton Inn Des Moines-Airport

Greater South Side

Crystal

฿3,752

฿4,202 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

A buffet setup with various food items, including fruits and cereals, and a soup station.

A hotel room with a grey sofa, a matching ottoman, a flat-screen TV on a wooden desk, a standing lamp, and a framed abstract painting on the wall.

A hotel with a stone facade, a covered entrance, and an American flag.

3. Homewood Suites by Hilton Des Moines Airport

Des Moines

Galen

฿3,914

฿4,384 total

includes taxes & fees

13 Sept - 14 Sept

A hotel dining area with multiple tables and chairs, a central fireplace, and potted plants.

A fitness center with treadmills, elliptical machines, and exercise equipment.

A hotel lobby with a fireplace, green patterned chairs, a television mounted above the fireplace, and a patterned carpet.

A hotel room with a large bed, a desk, a TV, and a window with curtains.

4. Fairfield Inn & Suites by Marriott Des Moines Airport

Des Moines

Richard

฿4,347

฿4,868 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a reception desk, seating area, and a kitchen visible in the background.

A modern hallway with wooden cabinets, a white countertop, and a tiled backsplash.

A bar area with a polished bar counter, a variety of bottles and glasses, and a well-lit ambiance.

5. Hilton Garden Inn Des Moines Airport

Des Moines

Sara

฿4,427

฿4,958 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

An indoor swimming pool with clear windows, white chairs, and a blue and white color scheme.

A brick building with a covered entrance and a car parked in front.

6. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

John

฿2,317

฿2,596 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio with a fire pit, wooden pergola, and seating area.

A modern living room with a fireplace, two sofas, a coffee table, and a bookshelf.

A person floating on a pink inflatable ring in a pool.

A hotel with a covered entrance, multiple floors, and a sign reading 'COUNTRY INN & SUITES BY PADIBOSON.'

7. Country Inn & Suites by Radisson, Indianola, IA

Indianola

Rachel

฿3,888

฿4,354 total

includes taxes & fees

1 Oct - 2 Oct

A modern hotel lobby with a central reception desk, seating area with sofas and chairs, and a self-service kiosk.

A modern gym with exercise equipment, a wall-mounted TV, and a mirror.

A modern lobby with a reception desk, colorful chairs, a purple sofa, and a wall with a 'SOUTHEAST' sign.

8. Tru By Hilton Norwalk Des Moines

Norwalk

Nathan

฿2,942

฿3,295 total

includes taxes & fees

1 Oct - 2 Oct

A modern hotel entrance with a glass facade, outdoor seating, and a staircase leading to the entrance.

An indoor swimming pool with a tiled floor, a diving board, and a variety of colorful lounge chairs.

A hotel room with a large bed, two bedside tables with lamps, a chair, and a patterned carpet.

A modern bathroom with a glass shower enclosure, dual sinks, and a large mirror.

9. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

Reginald

฿3,456

฿3,871 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio with brick walls, ceiling fans, string lights, and outdoor seating.

A modern hotel lobby with a seating area, a reception desk, and a visible exit sign.

A hotel room with three beds, a desk with a television, and a window with curtains.

A hotel entrance with a sign reading "hotel pommier."

10. Hotel Pommier Indianola

Indianola

Kelli

฿2,871

฿3,215 total

includes taxes & fees

7 Sept - 8 Sept

An indoor swimming pool with a 30 ft depth sign, a reception area, and a 'No Lifeguard' warning sign.

A lobby with striped orange chairs, a green ottoman, and a fireplace.

A spacious dining area with a long table and multiple chairs, large windows, and orange walls.

A hotel room with two beds, a desk, a television, and a dresser.

11. Drury Inn & Suites West Des Moines

West Des Moines

Justin

฿3,291

฿3,686 total

includes taxes & fees

20 Sept - 21 Sept

A reception desk with a stone facade, a 'Quality by Choice Hotels' sign, and pendant lighting.

A swimming pool with a checkered border, a sunroof, and a seating area with white tables and chairs.

A hotel room with a bed, a sofa, a coffee table, and a desk.

12. Quality Inn & Suites Des Moines Airport

Greater South Side

JAVIER

฿2,099

฿2,350 total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, a sofa, an ottoman, a nightstand, a lamp, and two framed pictures on the wall.

A modern hotel with a glass facade, a covered entrance, and a landscaped area.

13. Hyatt Place West Des Moines Jordan Creek

West Des Moines

Gary

฿3,555

฿3,982 total

includes taxes & fees

27 Sept - 28 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a wooden cabinet.

A Holiday Inn Express & Suites hotel with a modern design, featuring a mix of brick and glass facade, multiple entry points, and a well-lit exterior.

A hotel lobby with green armchairs, a sofa, a small table, and framed artwork on the walls.

A modern breakfast area with a self-serve station, a large apple-shaped sign, and a kitchen display.

14. Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

West Des Moines

Timothy

฿3,753

฿4,203 total

includes taxes & fees

28 Sept - 29 Sept

A modern restaurant with a central bar area, multiple seating options including booths and tables, and pendant lighting.

A modern bar area with a white countertop, black bar stools, and pendant lighting.

A modern living room with a fireplace, green upholstered chairs, a round coffee table, and a large painting on the wall.

An outdoor patio with stone walls, a fire pit, and outdoor seating.

15. Fairfield Inn & Suites by Marriott® Norwalk Des Moines

Norwalk

Jodi

฿3,157

฿3,536 total

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with clear blue water, surrounded by lounge chairs and umbrellas.

A reception area with a curved glass partition, a reception desk, and a stone accent wall.

A restaurant with multiple tables and chairs, a bar area, and neon signs for Corona and Modelo beer brands.

A spacious lobby with a reception desk, seating area, and a large window offering a view of the outdoors.

16. Clarion Inn Des Moines Airport

Watrous South

CHRISTINA

฿2,158

฿2,417 total

includes taxes & fees

7 Sept - 8 Sept

A reception desk with a sign reading "AmericInn" and a clock on the wall.

A spacious living area with a wooden dining table, a sofa, and a floral armchair.

A restaurant with wooden furniture, a chalkboard wall, and a ceiling fan.

A living room with a sofa, a coffee table, and a dining area with chairs.

17. AmericInn by Wyndham Des Moines Airport

Greater South Side

Milagros

฿2,127

฿2,382 total

includes taxes & fees

10 Sept - 11 Sept

A hotel room with a bed, a desk with a chair, a television, a framed picture on the wall, a sink, and a microwave.

A modern hotel lobby with a bar area, seating, and a large blue accent wall.

A Hampton Inn Suites hotel with a clear entrance, American flags, and a welcoming sign.

An outdoor patio with tables and chairs, a covered seating area, and a building with stone and brick facade.

18. Hampton Inn & Suites West Des Moines/SW Mall Area

West Des Moines

Ronald

฿3,212

฿3,598 total

includes taxes & fees

27 Sept - 28 Sept

A hotel lobby with a reception desk, seating area, and a wall with a floral mural.

A hotel room with a large bed, two bedside tables with lamps, a chair, a desk, and a large window with curtains.

A spacious lobby with multiple seating areas, including sofas and tables, and a visible kitchen area in the background.

A modern hotel with a stone facade, multiple windows, and a covered entrance.

19. Sleep Inn & Suites West Des Moines near Jordan Creek

West Des Moines

Chris

฿2,607

฿2,920 total

includes taxes & fees

27 Sept - 28 Sept

A hotel entrance with a stone facade, a sign above the entrance, and a covered walkway.

A buffet setup with a bowl of oranges and a container of fruit.

A hotel lobby with a reception desk, a brown sofa, a small armchair, a coffee table, and a fireplace.

A hotel room with a large bed, a desk with a chair, a lamp, and a window with curtains.

20. Cobblestone Inn & Suites - Winterset, IA

Winterset

Joseph

฿3,283

฿3,677 total

includes taxes & fees

13 Sept - 14 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top St. Marys Hotel Reviews

Sleep Inn & Suites West Des Moines near Jordan Creek

10/10 Excellent

"Great"

Quality Inn & Suites Des Moines Airport

8/10 Good

"We were dead tired from 4 days of helping our daughter to move. We checked in and received a room right on the first floor, only a few steps from the main desk. We dove in the shower and piled into bed! It was perfect! The only thing was that the AC didn't seem to be as cool as I wanted, but we slepted like corpses all night without being too warm."

Drury Inn & Suites West Des Moines

10/10 Excellent

"Nice rooms and friendly staff"

AmericInn by Wyndham Des Moines Airport

10/10 Excellent

"Everything was excellent"

Lakeside Hotel Casino, a Travelodge by Wyndham

10/10 Excellent

"The staff was extremely friendly and accommodating. Good experience all around."

Residence Inn by Marriott Des Moines West at Jordan Creek Town Center

10/10 Excellent

"."

More cheap stays in St. Marys

Quality Inn & Suites Des Moines Airport

5231 Fleur Dr Des Moines IA

฿2,099

฿2,350 total

28 Sept - 29 Sept

includes taxes & fees

7.6/10 Good! (1,002 reviews)

Days Inn & Suites by Wyndham Des Moines Airport

1901 Hackley Ave Des Moines IA

฿2,317

฿2,596 total

20 Sept - 21 Sept

includes taxes & fees

Sleep Inn & Suites West Des Moines near Jordan Creek

885 S 51st St West Des Moines IA

฿2,607

฿2,920 total

27 Sept - 28 Sept

includes taxes & fees

8.8/10 Excellent! (1,002 reviews)

Hampton Inn & Suites West Des Moines/SW Mall Area

6160 Mills Civic Parkway West Des Moines IA

฿3,212

฿3,598 total

27 Sept - 28 Sept

includes taxes & fees

Baymont by Wyndham Des Moines Airport

6221 Willow Creek Ave Des Moines IA

฿3,244

฿3,634 total

23 Sept - 24 Sept

includes taxes & fees

Hampton Inn Des Moines-Airport

5001 Fleur Dr Des Moines IA

฿3,752

฿4,202 total

13 Sept - 14 Sept

includes taxes & fees

Frequently asked questions

What's the best place for a stay in St. Marys?

Days Inn & Suites by Wyndham Des Moines Airport, located 16.6 mi (26.7 km) from the heart of St. Marys, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are AmericInn by Wyndham Des Moines Airport and Drury Inn & Suites West Des Moines. See all available top hotels, or vacation rentals in St. Marys.

If I need to cancel my hotel reservation in St. Marys, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in St. Marys.

What is staying in St. Marys like?

Travellers to St. Marys will find plenty to explore and enjoy. There are 166 hotels and other accommodation options in the surrounding area. Find out more about St. Marys.

What should I see while I'm in St. Marys?

Places to visit in the wider area include Lake Ahquabi State Park, National Balloon Museum and Clark Tower. You'll also find John Wayne Birthplace Museum and Blank Park Zoo in the area. Take a look at what more there is to see and do in Expedia's St. Marys guide.

What's the weather like in St. Marys?

The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -2°C. The snowiest months in St. Marys are January, February, November and March, with each month seeing an average of 22 cm of snowfall.

Explore a world of travel with Expedia

More ways to book

Book Hotels in St. Marys on Expedia.com

Find hotels in St. Marys, IA from ฿2,350

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in St. Marys

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for St. Marys hotels

1. Baymont by Wyndham Des Moines Airport

2. Hampton Inn Des Moines-Airport

3. Homewood Suites by Hilton Des Moines Airport

4. Fairfield Inn & Suites by Marriott Des Moines Airport

5. Hilton Garden Inn Des Moines Airport

6. Days Inn & Suites by Wyndham Des Moines Airport

7. Country Inn & Suites by Radisson, Indianola, IA

8. Tru By Hilton Norwalk Des Moines

9. Holiday Inn Des Moines-Airport/Conf Center by IHG

10. Hotel Pommier Indianola

11. Drury Inn & Suites West Des Moines

12. Quality Inn & Suites Des Moines Airport

13. Hyatt Place West Des Moines Jordan Creek

14. Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

15. Fairfield Inn & Suites by Marriott® Norwalk Des Moines

16. Clarion Inn Des Moines Airport

17. AmericInn by Wyndham Des Moines Airport

18. Hampton Inn & Suites West Des Moines/SW Mall Area

19. Sleep Inn & Suites West Des Moines near Jordan Creek

20. Cobblestone Inn & Suites - Winterset, IA

Top St. Marys Hotel Reviews

Sleep Inn & Suites West Des Moines near Jordan Creek

Quality Inn & Suites Des Moines Airport

Drury Inn & Suites West Des Moines

AmericInn by Wyndham Des Moines Airport

Lakeside Hotel Casino, a Travelodge by Wyndham

Residence Inn by Marriott Des Moines West at Jordan Creek Town Center

More cheap stays in St. Marys

Quality Inn & Suites Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

Sleep Inn & Suites West Des Moines near Jordan Creek

Hampton Inn & Suites West Des Moines/SW Mall Area

Baymont by Wyndham Des Moines Airport

Hampton Inn Des Moines-Airport

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app