Clayton Travel Guide

St. Louis

The illuminated Gateway Arch at night with a city skyline in the background.
A city skyline with a prominent arch bridge reflecting on the water.
A city skyline with a prominent arch bridge at sunset.
A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.
A historic building with a courtyard, surrounded by lush green grass and trees.

Stay near popular Clayton attractions

Washington University in St. Louis

8.8/10 (1,777 reviews)
Explore the campus of Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
See properties

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

฿794
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis: Museum of Illusions Entry Ticket

St. Louis: Museum of Illusions Entry Ticket

฿1,158
per adult
88% of travellers recommend
St. Louis: Museum of Illusions Entry Ticket
Saint Louis Self Guided Driving and Walking Audio Tour

St. Louis & Gateway Arch NP Self Guided Drive & Walk Audio Tour

฿562
per traveller
St. Louis & Gateway Arch NP Self Guided Drive & Walk Audio Tour
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

฿5,791
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Downtown St. Louis Smartphone Guided Audio Walking Tour App

Downtown St. Louis Smartphone Guided Audio Walking Tour App

฿256
per adult
100% of travellers recommend
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Landmarks Downtown-West Walking Tour

Landmarks Downtown-West Walking Tour

฿662
per adult
Landmarks Downtown-West Walking Tour
See all activities in St. Louis

Top hotels in Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿3,037 per night from 30 Aug to 31 Aug
฿3,037
฿3,545 total
30 Aug - 31 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,338 reviews)
"Very helpful and courteous staff."

Reviewed on 17 Aug 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ฿5,043 per night from 23 Aug to 24 Aug
฿5,043
฿5,937 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is ฿4,027 per night from 23 Aug to 24 Aug
฿4,027
฿4,701 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park are ...
AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
The price is ฿4,321 per night from 23 Aug to 24 Aug
฿4,321
฿5,088 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the helpful staff in their ...
8.8/10 Excellent! (1,004 reviews)
"Everything and every were excellent."

Reviewed on 16 Aug 2026

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ฿4,444 per night from 28 Aug to 29 Aug
฿4,444
฿5,241 total
28 Aug - 29 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is ฿3,311 per night from 2 Sept to 3 Sept
฿3,311
฿4,847 total
2 Sept - 3 Sept
includes taxes & fees
Stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (2,222 reviews)
"Smell of fish in the hall outside room. Otherwise great."

Reviewed on 15 Aug 2026

Hollywood Casino & Hotel St. Louis
See all 1,986 properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Clayton

Find the best Clayton areas for the activities you enjoy most. Learn more about Clayton
Learn more about Clayton
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

An ornate hall with arched ceilings and intricate patterns.
Photo by Terry Eaves
Open Photo by Terry Eaves

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Clayton Travel Guide