Search Hotels in Clayton, St. Louis

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
7 Oct - 8 Oct
Tomorrow
8 Oct - 9 Oct
This weekend
10 Oct - 12 Oct
Next weekend
17 Oct - 19 Oct

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Clayton, St. Louis

Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2958)
"Great staff and hotel!"
The price is ฿3,342
฿3,901 total
includes taxes & fees
19 Oct - 20 Oct
Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton
2 bars/lounges, rooftop bar

AC Hotel St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (192)
"Enjoyed my stay"
The price is ฿4,218
฿4,924 total
includes taxes & fees
19 Oct - 20 Oct
AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (663)
"The room was clean and service was excellent."
The price is ฿5,209
฿6,133 total
includes taxes & fees
2 Nov - 3 Nov
Le Méridien St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Outdoor dining

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property
9.0 out of 10, Wonderful, (884)
"Will definitely stay again."
The price is ฿4,097
฿4,824 total
includes taxes & fees
26 Oct - 27 Oct
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Homewood Suites by Hilton St Louis - Galleria
Exterior

Homewood Suites by Hilton St Louis - Galleria

3.0 star property
8.0 out of 10, Very good, (1002)
"The staff was friendly"
The price is ฿4,137
฿4,912 total
includes taxes & fees
26 Oct - 27 Oct
Homewood Suites by Hilton St Louis - Galleria
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (550)
"Service is exceptional!!!"
The price is ฿20,083
฿23,445 total
includes taxes & fees
2 Nov - 3 Nov
The Ritz-Carlton, St. Louis
Residence Inn By Marriott St. Louis Clayton
View from property

Residence Inn By Marriott St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (182)
"Nice, large room. Quiet."
The price is ฿5,224
฿6,281 total
includes taxes & fees
31 Oct - 1 Nov
Residence Inn By Marriott St. Louis Clayton
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very good, (573)
"Staff was excellent and the court yard was a wonderful place to sit and have a glass of wine. The upscale bathroom is off the charts! "
The price is ฿4,542
฿5,613 total
includes taxes & fees
12 Oct - 13 Oct
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (3117)
"Wonderful hotel only place we will stay"
The price is ฿4,412
฿5,159 total
includes taxes & fees
20 Oct - 21 Oct
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2709)
"Friendly staff, clean rooms, and convenient! "
The price is ฿2,920
฿3,437 total
includes taxes & fees
20 Oct - 21 Oct
Pear Tree Inn St. Louis Airport
Drury Inn & Suites St. Louis Union Station
Indoor pool

Drury Inn & Suites St. Louis Union Station

3.0 star property
9.4 out of 10, Exceptional, (1249)
"Great property wonderful staff"
The price is ฿3,861
฿4,591 total
includes taxes & fees
13 Oct - 14 Oct
Drury Inn & Suites St. Louis Union Station
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.6 out of 10, Excellent, (3994)
"Wonderful stay."
The price is ฿3,963
฿4,673 total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency St. Louis at The Arch
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1902)
"Great staff; nice rooftop"
The price is ฿4,412
฿5,248 total
includes taxes & fees
3 Nov - 4 Nov
Moonrise Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.2 out of 10, Very good, (1010)
"Clean room and staff was great "
The price is ฿2,758
฿3,185 total
includes taxes & fees
2 Nov - 3 Nov
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Embassy Suites by Hilton St. Louis Downtown
Exterior

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
8.8 out of 10, Excellent, (1217)
"Good Hotel"
The price is ฿3,902
฿4,640 total
includes taxes & fees
2 Nov - 3 Nov
Embassy Suites by Hilton St. Louis Downtown
21C Museum Hotel St Louis
Interior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1402)
"Wonderful stay! "
The price is ฿4,942
฿5,940 total
includes taxes & fees
2 Nov - 3 Nov
21C Museum Hotel St Louis
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1586)
"We enjoyed our stay!"
The Wildwood Hotel
The West End
Terrace/patio

The West End

2.0 star property
8.4 out of 10, Very good, (335)
"hotel rooms were very clean. it was a nice quiet hotel. loved my stay"
The West End
Live by Loews - St.Louis
Breakfast, lunch and dinner served

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1051)
"Incredible hotel! "
The price is ฿5,483
฿6,521 total
includes taxes & fees
12 Oct - 13 Oct
Live by Loews - St.Louis
The Cheshire
Terrace/patio

The Cheshire

4.0 star property
8.6 out of 10, Excellent, (1005)
"Great staff, wonderful property."
The price is ฿3,735
฿4,435 total
includes taxes & fees
26 Oct - 27 Oct
The Cheshire
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Clayton

Find the best Clayton areas for the activities you enjoy most. Learn more about Clayton
Learn more about Clayton

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Central West End

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Lewis & Clark Boathouse and Nature Center while in the area.

St. Louis showing interior views

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Clayton Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Clean room and staff was great "
Beth 2-night trip
Posted 1 day ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Clayton?
Clayton is a welcoming neighbourhood known for its array of dining options and sporting events. Make sure that you visit Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.
Where is the best place to stay in Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Clayton. This hotel offers 2 restaurants and 2 bars. Other top choices in the neighbourhood include The Ritz-Carlton, St. Louis and Residence Inn By Marriott St. Louis Clayton.
How many hotels will I find in Clayton?
With 10 Expedia hotels and other accommodation options in Clayton to choose from, this is a good starting point for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Clayton, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the top deals on offer in Clayton.
What are the top things to see and do in Clayton?
A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, Tao Tennis Center and Center of Creative Arts are also worth a stop.
How can I get around Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.