The Best Hotels in Clayton, St. Louis - 2026 Updated Prices

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Property	Property class	Guest rating
Residence Inn By Marriott St. Louis Clayton	3.0 star property	9.4 Exceptional 248 reviews	View
AC Hotel St. Louis Clayton	2.0 star property	9.2 Wonderful 421 reviews	View
The Ritz-Carlton, St. Louis	5.0 star property	9.2 Wonderful 586 reviews	View
Clayton Plaza Hotel & Extended Stay	3.5 star property	9.0 Wonderful 3,514 reviews	View
Le Méridien St. Louis Clayton	4.0 star property	8.8 Excellent 797 reviews	View

Where to stay in Clayton

Find the best Clayton areas for the activities you enjoy most. Learn more about Clayton

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A large airplane suspended in a net structure in an urban setting with modern buildings in the background.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

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Top Clayton Hotel Reviews

Hyatt Regency St. Louis at The Arch

8/10 Good

"Over all, our stay was fine. Staff was very kind. We visited for an event that took place in one of the 2nd floor ballrooms where I was a vendor. The food served for us at breakfast was delicious. However, one of the first things that happened to me upon getting to our room was my mother coming out from the bathroom and going, "Uh, someone pooped in our shower?". Turns out, it was just a very convincing rust spot, so I'm glad we didn't complain and look completely foolish, but still. The beds were comfortable though, and the water ran quite hot. The halls are a bit of a twist-and-turn to navigate and we were on the side of the building facing the MLK Bridge, which is a nice view. You are, however, literally right next to the Arch. All you have to do is step outside on Chestnut street and look to your left. The bar and common areas downstairs were nicely furnished; I spent some time with my laptop down there while my travel companions turned in early. Interesting spot to people watch. They also have a designated area for DoorDashers and other delivery folks to leave items, but I was usually waiting for them right at the door. My only complaint is that parking is far too high! We parked down the street a bit instead, and other than our GPS leading us on the longest route back to the hotel imaginable, we saved at least $50 on our two night stay, and the garage was perfectly walkable, even with our luggage and vending supplies."

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Even though most of the reviews were great, I was still skeptical because I've had a horrible experience at a highly rated hotel. I must say, the people were telling the truth! The staff was super nice, and the rooms were cleaned. I especially like being able to control the shower temperature digitally. The only downside is that the light in the room is super dim, not great for older eyes. Also, some of the furniture in the room could stand a good deep cleaning. I spray everything down like a mad woman, though. The breakfast buffet was good; however, it never changed in the 3 days I was there, and things like the hash browns and oatmeal were cold. The pool was warm, but could stand a cleaning. Overall, I would stay here again because it was within a 15-minute drive from all of my activities, and as I said, the staff was very nice."

Live by Loews - St.Louis

10/10 Excellent

"This was the perfect spot to stay for the weekend. Came up for the Hockey game and wanted a unique experience of downtown STL while also feeling safe. The staff is extremely welcoming and the overall feel is not overwhelming, it’s super clean, and being right next Busch Ballpark is awesome with great views. Parking deck is tight but easy to access. Cannot wait to go back during a baseball game and stay here."

Frequently asked questions

What's it like in Clayton?

Clayton is a welcoming neighbourhood known for its array of dining options and sporting events. Make sure that you visit Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center as part of your Clayton travel plans.

Where is the best place to stay in Clayton?

Based on our traveller data, Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay in Clayton. This hotel offers free breakfast and an indoor pool. Other good choices for your stay in the neighbourhood include AC Hotel St. Louis Clayton and Le Méridien St. Louis Clayton.

How many hotels will I find in Clayton?

Expedia has 21 hotels and other accommodation options in Clayton to choose from, making this an ideal home base for exploring the greater St. Louis area.

If I need to cancel my hotel reservation in Clayton, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the top deals on offer in Clayton.

What are the top things to see and do in Clayton?

A few attractions you might want to check out while you're in Clayton are Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. When you're sightseeing in St. Louis, St. Louis Zoo and Tao Tennis Center are also worth a stop.

How can I get around Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.

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Our top choices for Clayton hotels

1. Residence Inn By Marriott St. Louis Clayton

2. The Ritz-Carlton, St. Louis

3. Le Méridien St. Louis Clayton

4. AC Hotel St. Louis Clayton

5. Clayton Plaza Hotel & Extended Stay

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

7. Homewood Suites by Hilton St Louis - Galleria

8. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

9. The Knight Center at Washington University

10. SpringHill Suites St. Louis Brentwood

11. The Cheshire

12. Drury Plaza Hotel St. Louis Brentwood

13. Moonrise Hotel

14. Hampton Inn & Suites St. Louis at Forest Park

15. Wingate by Wyndham St. Louis Airport

16. Renaissance St. Louis Airport Hotel

17. Home2 Suites by Hilton St. Louis/Forest Park

18. The Royal Sonesta Chase Park Plaza St. Louis

19. Hampton Inn By Hilton St Louis Airport

20. DoubleTree by Hilton St. Louis Forest Park

Compare popular hotels in Clayton

Where to stay in Clayton

Downtown St. Louis

St. Charles Historic District

Central West End

Creve Coeur

Downtown West

Top Clayton Hotel Reviews

Hyatt Regency St. Louis at The Arch

Frequently asked questions

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