Clayton Travel Guide

St. Louis

Clayton
Photo by Najib Tecle
Photo by kirk allen
Photo by Sarah Mather

Popular places to visit

Things to do


Top hotels in Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is ฿3,342 per night from 19 Oct to 20 Oct
฿3,342
฿3,893 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,947 reviews)
"Great breakfast with homemade omelets. Even the cook was friendly and joking with us. Rooms were clean, great comfortable bed. Shower was large and took shower without getting hair wet(a plus to me). Humidity controlled mirror helped to get us in and out fast. Overall excellent service."

Reviewed on 30 Sept 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave, St. Louis, MO
The price is ฿3,959 per night from 2 Nov to 3 Nov
฿3,959
฿4,612 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (188 reviews)
"My room was very cold"

Reviewed on 30 Sept 2025

AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave, St. Louis, MO
The price is ฿5,210 per night from 2 Nov to 3 Nov
฿5,210
฿6,121 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (659 reviews)
"The room was clean and service was excellent."

Reviewed on 7 Sept 2025

Le Méridien St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ฿4,098 per night from 31 Oct to 1 Nov
฿4,098
฿4,815 total
31 Oct - 1 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the helpful staff in their ...
8.8/10 Excellent! (883 reviews)
"Friendly and helpful people. They can improve breakfast options. Breakfast was the only negative"

Reviewed on 15 Sept 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
The price is ฿4,413 per night from 19 Oct to 20 Oct
฿4,413
฿5,160 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,122 reviews)
"I walked to the Arch a few times. The rooftop was amazing."

Reviewed on 30 Sept 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
The price is ฿3,959 per night from 2 Nov to 3 Nov
฿3,959
฿4,669 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,971 reviews)
"Great stay"

Reviewed on 30 Sept 2025

Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Clayton

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Dogtown

When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.

Dogtown
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University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
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Ladue

Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out.

Ladue
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The Hill

While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.

The Hill
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
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The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove


Clayton Travel Guide