TOP Casino Hotels in St. Charles, MO for 2026

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Our top choices for St. Charles hotels with a casino

A brick building with a sign reading "Country Inn & Suites."

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

1. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

Stewart

฿4,133

฿4,750 total

includes taxes & fees

22 Nov - 23 Nov

A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

A large hotel building with a prominent sign for 'Embassy Suites.'

A grand hotel lobby with a central spiral staircase, multiple balconies, and a large indoor plant.

A reception area with three counters, each equipped with a computer and a phone. The walls are adorned with framed artwork.

2. Embassy Suites by Hilton St. Louis St. Charles

St. Charles

Elyse

฿4,402

฿5,059 total

includes taxes & fees

22 Nov - 23 Nov

A modern meeting room with a long table, comfortable seating, and a brick wall backdrop.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

A hotel room with a large bed, a desk, a chair, and a window with a view.

3. Hampton Inn & Suites St. Charles Old Town Area

St. Charles

Sara

฿3,989

฿4,793 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

4. Comfort Suites St Charles - St Louis

St. Charles

Bryan

฿3,137

฿3,605 total

includes taxes & fees

1 Nov - 2 Nov

A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

A bakery display case with various pastries and cakes.

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

5. Ameristar Casino Resort and Spa

St. Charles

Samuel

฿5,375

฿6,842 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

A living room with a brown leather sectional sofa, a glass coffee table, a wooden side table with drawers, a mirror, and a framed picture on the wall.

An indoor swimming pool with clear water, surrounded by chairs and a covered area.

A kitchenette with a coffee machine, a coffee dispenser, and a coffee maker.

6. Super 8 by Wyndham St Charles

St. Charles

Patrick

฿2,696

฿3,099 total

includes taxes & fees

1 Nov - 2 Nov

A multi-story hotel with a parking lot in front.

A person operating a front-loading washing machine in a laundromat with multiple machines.

A person in military uniform at a counter with a computer monitor, a card reader, and a coffee machine.

A hallway with a reception desk, a no-smoking sign, and a door.

7. WoodSpring Suites St Louis St Charles

St. Charles

Erica

฿2,868

฿3,296 total

includes taxes & fees

25 Oct - 26 Oct

A large hotel with a prominent tower and multiple parking areas.

A bar area with a long counter, multiple screens, and seating.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

8. Hollywood Casino & Hotel St. Louis

Riverport

Nicole

฿3,186

฿4,238 total

includes taxes & fees

2 Nov - 3 Nov

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Top St. Charles Hotel Reviews

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"The room was clean. The staff was friendly and inviting."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Our first time staying here, very near the airport but it won’t be the last. Solid facility and great staff with 24/7 shuttle service."

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent

"We really enjoyed our stay! The two-room suite was spacious, clean, and comfortable. Having a separate living area, two TVs, a microwave, and a mini fridge was especially convenient. The complimentary breakfast was enjoyable, and the hotel was generally quiet. The bathroom could use some updating, and an exhaust fan would have been appreciated. Overall, it was a pleasant stay, and we would definitely stay here again!"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Loved the location, amenities and large room with comfortable bed. We were able to walk to Enterprise Center. Particularly enjoyed the happy hour and breakfast. Did not appreciate the noise from the garbage collectors handling the huge dumpsters around 4am. For an upscale quality hotel you should contract to have quiet hours like midnight to 8am with any businesses your guest rooms face."

Ameristar Casino Resort and Spa

10/10 Excellent

"Great place"

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"We enjoyed the fresh popcorn and it was within walking distance from the train station."

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"just a. overnight stop & was great"

Hampton Inn St. Charles St. Peters

10/10 Excellent

"The hotel was in a great location close to restaurants and shopping, and seemed like a very safe area. The beds were very comfortable!"

Frequently asked questions

Searching for casino hotels in St. Charles?

Heading to St. Charles for some gaming? Lucky for you, you'll find Ameristar Casino St. Charles here, not to mention a lot more to see and do. Tourists speak highly of the historic landmarks, family-friendly activities and local cuisine. You might want to visit popular sights in the larger area including St. Louis Zoo.

What's the best hotel for some casino gaming in St. Charles?

Ameristar Casino Resort and Spa is a top hotel featuring a casino and a full-service spa.

How many hotels that are good for gaming are there in St. Charles?

Get your game on at one of Expedia's 178 lodging options in St. Charles.

When should I take my casino trip to St. Charles?

You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.

What is there to do in St. Charles?

Lucky gamers can head to Westport Plaza, Mid Rivers Mall and St. Louis Premium Outlets to spend their winnings. St. Charles is known for its historic sites and live music, and you can visit cultural spots such as Missouri Artists on Main, Hollywood Casino Amphitheatre and The Factory. In addition, you might want to visit Historic Main Street and Katy Trail.

What are my transportation options for my casino getaway to St. Charles?

Getting around St. Charles is easier with these transportation options: You can book a flight to the nearest airport, which is Lambert-St. Louis International Airport (STL), located 7.7 mi (12.5 km) from the city centre. If you'd like to venture out around the area, consider renting a car to explore more sights.

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Check availability on St. Charles Casino Hotels

Our top choices for St. Charles hotels with a casino

1. Country Inn & Suites by Radisson, St. Charles Historic District

2. Embassy Suites by Hilton St. Louis St. Charles