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Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for St. Charles hotels with a casino

A brick building with a sign reading "Country Inn & Suites."

1. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,111 reviews)
"Very convenient to downtown St Charles. As per previous visits this hotel is excellent for the price range of the rooms."
United States
Stewart
The price is ฿4,291
฿4,932 total
includes taxes & fees
29 Nov - 30 Nov
Country Inn & Suites by Radisson, St. Charles Historic District
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

2. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,000 reviews)
"Great place to stay"
United States
Elyse
The price is ฿4,381
฿5,035 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites by Hilton St. Louis St. Charles
A modern kitchen with a central island, breakfast bar, and various appliances.

3. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.2 out of 10, Wonderful, (758 reviews)
"Great stay!"
United States
Sara
The price is ฿3,970
฿4,770 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites St. Charles Old Town Area
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

4. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,000 reviews)
"Great stay."
United States
Bryan
The price is ฿3,085
฿3,545 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Suites St Charles - St Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,091 reviews)
"Great place"
United States
Samuel
The price is ฿5,374
฿6,841 total
includes taxes & fees
22 Nov - 23 Nov
Ameristar Casino Resort and Spa
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

6. Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,002 reviews)
"Clean room, staff was polite and helpful!"
United States
Tammie
The price is ฿2,656
฿3,053 total
includes taxes & fees
6 Dec - 7 Dec
Super 8 by Wyndham St Charles
A hallway with a reception desk, a no-smoking sign, and a door.

7. WoodSpring Suites St Louis St Charles

WoodSpring Suites St Louis St Charles
2.5 star property
St. Charles
5.6 out of 10, (308 reviews)
"Clean and staff was nice."
United States
Erica
The price is ฿2,856
฿3,282 total
includes taxes & fees
9 Nov - 10 Nov
WoodSpring Suites St Louis St Charles
A bar area with a long counter, multiple screens, and seating.

8. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
Riverport
8.6 out of 10, Excellent, (2,243 reviews)
"Always love staying here! Rooms are so spacious and comfy"
United States
Shayla
The price is ฿2,336
฿3,235 total
includes taxes & fees
6 Dec - 7 Dec
Hollywood Casino & Hotel St. Louis
A spacious bar area with a long wooden counter, multiple bar stools, and a variety of bar tools.

9. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
Earth City
7.6 out of 10, Good, (1,000 reviews)
"It was clean and have no complaints."
United States
Vincent
The price is ฿2,531
฿2,936 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn St. Louis Arpt West-Earth City by IHG
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

10. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1,012 reviews)
"Loved my stay"
United States
Thadora
The price is ฿3,684
฿4,568 total
includes taxes & fees
19 Nov - 20 Nov
Hyatt Select St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

A modern kitchen with a central island, breakfast bar, and various appliances.
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
St. Charles

10/10 Excellent

Everything was good from arrival, staff very helpful and good breakfast
United Kingdom
Nicola
Reviewed August 3, 2026
Hampton Inn & Suites St. Charles Old Town Area

Frequently Asked Questions

Searching for casino hotels in St. Charles?

Heading to St. Charles for some gaming? Lucky for you, you'll find Ameristar Casino St. Charles here, not to mention a lot more to see and do. Tourists speak highly of the historic landmarks, family-friendly activities and local cuisine. You might want to visit popular sights in the larger area including St. Louis Zoo.

What's the best hotel for some casino gaming in St. Charles?

Ameristar Casino Resort and Spa is a top hotel featuring a casino and a full-service spa.

How many hotels that are good for gaming are there in St. Charles?

Get your game on at one of Expedia's 178 lodging options in St. Charles.

When should I take my casino trip to St. Charles?

You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.

What is there to do in St. Charles?

Lucky gamers can head to Westport Plaza, Mid Rivers Mall and St. Louis Premium Outlets to spend their winnings. St. Charles is known for its historic sites and live music, and you can visit cultural spots such as Missouri Artists on Main, Hollywood Casino Amphitheatre and The Factory. In addition, you might want to visit Historic Main Street and Katy Trail.

What are my transportation options for my casino getaway to St. Charles?

Getting around St. Charles is easier with these transportation options: You can book a flight to the nearest airport, which is Lambert-St. Louis International Airport (STL), located 7.7 mi (12.5 km) from the city centre. If you'd like to venture out around the area, consider renting a car to explore more sights.