TOP Casino Hotels in St. Charles, MO for 2026

A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

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Our top choices for St. Charles hotels with a casino

A brick building with a sign reading "Country Inn & Suites."

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

1. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

Roseanna

฿4,459

฿5,124 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.

A hotel room with a sofa, armchairs, a coffee table, a desk, and a large window with curtains.

A grand staircase with a wooden railing leading to a lower level, surrounded by potted plants and a patterned carpet.

A multi-story hotel with a central courtyard, a parking lot, and a green-roofed building.

2. Embassy Suites by Hilton St. Louis St. Charles

St. Charles

Anonymous traveller

฿4,651

฿5,345 total

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen with a central island, breakfast bar, and various appliances.

A hotel room with a large bed, a desk, a chair, and a window with a view.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

3. Hampton Inn & Suites St. Charles Old Town Area

St. Charles

Daniel

฿3,825

฿4,602 total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

4. Comfort Suites St Charles - St Louis

St. Charles

Bryan

฿3,235

฿3,718 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A bakery display case with various pastries and cakes.

A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

5. Ameristar Casino Resort and Spa

St. Charles

Laura

฿5,677

฿7,191 total

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

An indoor swimming pool with clear water, surrounded by chairs and a covered area.

A bathroom with a sink, toilet, and shower.

A kitchenette with a coffee machine, a coffee dispenser, and a coffee maker.

6. Super 8 by Wyndham St Charles

St. Charles

Cortney

฿2,681

฿3,082 total

includes taxes & fees

1 Nov - 2 Nov

A person in military uniform at a counter with a computer monitor, a card reader, and a coffee machine.

A hallway with a reception desk, a no-smoking sign, and a door.

A person sitting on a bed with a laptop, wearing a white shirt and a patterned tie.

7. WoodSpring Suites St Louis St Charles

St. Charles

Erica

฿2,852

฿3,278 total

includes taxes & fees

5 Oct - 6 Oct

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

Three people at a bar with a neon sign reading "RODEO Hollywood Casino".

A bar area with a long counter, multiple screens, and seating.

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

8. Hollywood Casino & Hotel St. Louis

Riverport

Nicole

฿2,794

฿4,287 total

includes taxes & fees

1 Nov - 2 Nov

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Top St. Charles Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Nice hotel"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Great location Easy parking Wonderful staff Clean room"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"I have no complaints about this hotel. The staff was pleasant and helpful. It was wonderfully clean throughout. The Renaissance Hotel has my highest recommendation as a wonderful place to stay."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"This location was one of the best hotel experiences I've had in America. The only deficiency with my stay here, was it wasn't long enough. I'd stay for a week next time, and there will be a next time."

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"Everything was very clean. All the staff was wonderful. The room was perfect. Thank you! I will definitely stay here again."

Comfort Suites St Charles - St Louis

8/10 Good

"Second time staying here for the St. Charles Oktoberfest. Reasonably priced for how close to the fest it is."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Walking distance to Lambo"

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent

"I stayed in St Charles Missouri and Geneva was awesome she was at the front desk during check-in and she was great"

Frequently asked questions

Searching for casino hotels in St. Charles?

Heading to St. Charles for some gaming? Lucky for you, you'll find Ameristar Casino St. Charles here, not to mention a lot more to see and do. Tourists speak highly of the historic landmarks, family-friendly activities and local cuisine. You might want to visit popular sights in the larger area including St. Louis Zoo.

What's the best hotel for some casino gaming in St. Charles?

Ameristar Casino Resort and Spa is a top hotel featuring a casino and a full-service spa.

How many hotels that are good for gaming are there in St. Charles?

Get your game on at one of Expedia's 178 lodging options in St. Charles.

When should I take my casino trip to St. Charles?

You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.

What is there to do in St. Charles?

Lucky gamers can head to Westport Plaza, Mid Rivers Mall and St. Louis Premium Outlets to spend their winnings. St. Charles is known for its historic sites and live music, and you can visit cultural spots such as Missouri Artists on Main, Hollywood Casino Amphitheatre and The Factory. In addition, you might want to visit Historic Main Street and Katy Trail.

What are my transportation options for my casino getaway to St. Charles?

Getting around St. Charles is easier with these transportation options: You can book a flight to the nearest airport, which is Lambert-St. Louis International Airport (STL), located 7.7 mi (12.5 km) from the city centre. If you'd like to venture out around the area, consider renting a car to explore more sights.

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Room 1

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Check availability on St. Charles Casino Hotels

Our top choices for St. Charles hotels with a casino

1. Country Inn & Suites by Radisson, St. Charles Historic District

2. Embassy Suites by Hilton St. Louis St. Charles