TOP Casino Hotels in St. Charles, MO for 2026

A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

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Our top choices for St. Charles hotels with a casino

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

1. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District

Roseanna

฿4,471

฿5,139 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.

A multi-story hotel with a central courtyard, a parking lot, and a green-roofed building.

A high-rise hotel with multiple floors, each featuring balconies with red railings and green plants. The interior includes a central atrium with a winding pathway and seating areas.

A hotel room with a sofa, armchairs, a coffee table, a desk, and a large window with curtains.

2. Embassy Suites by Hilton St. Louis St. Charles

St. Charles

Anonymous traveller

฿4,651

฿5,345 total

includes taxes & fees

13 Oct - 14 Oct

A modern kitchen with a central island, breakfast bar, and various appliances.

A modern hotel lobby with a seating area, a coffee station, and a large window providing natural light.

A hotel room with a large bed, a desk, a chair, and a window with a view.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

3. Hampton Inn & Suites St. Charles Old Town Area

St. Charles

Daniel

฿3,825

฿4,602 total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

4. Comfort Suites St Charles - St Louis

St. Charles

Bryan

฿3,325

฿3,822 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A bar area with multiple seating arrangements, a stage, and a chandelier.

A bakery display case with various pastries and cakes.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

5. Ameristar Casino Resort and Spa

St. Charles

Melissa

฿5,695

฿7,214 total

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

An indoor swimming pool with clear water, surrounded by chairs and a covered area.

A living room with a brown leather sectional sofa, a glass coffee table, a wooden side table with drawers, a mirror, and a framed picture on the wall.

A bathroom with a sink, toilet, and shower.

6. Super 8 by Wyndham St Charles

St. Charles

Cortney

฿2,681

฿3,082 total

includes taxes & fees

1 Nov - 2 Nov

A person in military uniform at a counter with a computer monitor, a card reader, and a coffee machine.

A person sitting on a bed with a laptop, wearing a white shirt and a patterned tie.

A hallway with a reception desk, a no-smoking sign, and a door.

7. WoodSpring Suites St Louis St Charles

St. Charles

Erica

฿2,852

฿3,278 total

includes taxes & fees

15 Oct - 16 Oct

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

A large hotel with a prominent tower and multiple parking areas.

Three people at a bar with a neon sign reading "RODEO Hollywood Casino".

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

8. Hollywood Casino & Hotel St. Louis

Riverport

Nicole

฿2,794

฿4,287 total

includes taxes & fees

1 Nov - 2 Nov

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Top St. Charles Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Very friendly and helpful staff. Good breakfast and clean room."

Ameristar Casino Resort and Spa

10/10 Excellent

"Perfect place to stay, for a fun weekend. The pool was amazing!"

Comfort Suites St Charles - St Louis

8/10 Good

"Nice place"

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent

"Great location to next door restaurant, quite a walk into the old town for other choices but lots of parking behind all buildings. Hotel was modern and comfortable, free parking. Only complaint was the swimming pool water was COLD for an indoor pool."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Very friendly staff."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"It was a great hotel located in a very neat part of town. It was clean and fit our needs perfectly."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Walking distance to Lambo"

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"We stayed at this hotel several times over the years and they never disappoint! Rooms are in very good condition and clean. Staff is pleasant and professional. The breakfast and late afternoon food and drinks are wonderful options to start and end the day. The location is very walkable to shopping and eating."

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent

"I stayed in St Charles Missouri and Geneva was awesome she was at the front desk during check-in and she was great"

Frequently asked questions

Searching for casino hotels in St. Charles?

Heading to St. Charles for some gaming? Lucky for you, you'll find Ameristar Casino St. Charles here, not to mention a lot more to see and do. Tourists speak highly of the historic landmarks, family-friendly activities and local cuisine. You might want to visit popular sights in the larger area including St. Louis Zoo.

What's the best hotel for some casino gaming in St. Charles?

Ameristar Casino Resort and Spa is a top hotel featuring a casino and a full-service spa.

How many hotels that are good for gaming are there in St. Charles?

Get your game on at one of Expedia's 178 lodging options in St. Charles.

When should I take my casino trip to St. Charles?

You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.

What is there to do in St. Charles?

Lucky gamers can head to Westport Plaza, Mid Rivers Mall and St. Louis Premium Outlets to spend their winnings. St. Charles is known for its historic sites and live music, and you can visit cultural spots such as Missouri Artists on Main, Hollywood Casino Amphitheatre and The Factory. In addition, you might want to visit Historic Main Street and Katy Trail.

What are my transportation options for my casino getaway to St. Charles?

Getting around St. Charles is easier with these transportation options: You can book a flight to the nearest airport, which is Lambert-St. Louis International Airport (STL), located 7.7 mi (12.5 km) from the city centre. If you'd like to venture out around the area, consider renting a car to explore more sights.

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Room 1

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Check availability on St. Charles Casino Hotels

Our top choices for St. Charles hotels with a casino

1. Country Inn & Suites by Radisson, St. Charles Historic District

2. Embassy Suites by Hilton St. Louis St. Charles