Search Hotels in Southwest Garden, St. Louis

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southwest Garden hotels

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
30.1 km from Southwest Garden
8.0 out of 10, Very good, (1000)
"I'd stay at this place again. "
United States
Suzanne
The price is ฿2,376
฿2,731 total
includes taxes & fees
29 Dec - 30 Dec
Super 8 by Wyndham St Charles

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
25.8 km from Southwest Garden
8.6 out of 10, Excellent, (772)
"Great hotel! "
United States
Royally
The price is ฿3,150
฿3,651 total
includes taxes & fees
28 Dec - 29 Dec
Tru by Hilton St. Charles St. Louis, MO

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
25.9 km from Southwest Garden
8.4 out of 10, Very good, (1000)
"Nice staff at reception. "
United States
Denise
The price is ฿2,448
฿2,813 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites St Charles - St Louis

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
25.7 km from Southwest Garden
9.2 out of 10, Wonderful, (636)
"Huge room. Great breakfast. "
United States
David
The price is ฿3,412
฿4,113 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites St. Charles Old Town Area

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
25.4 km from Southwest Garden
8.4 out of 10, Very good, (1008)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ฿4,779
฿6,106 total
includes taxes & fees
23 Dec - 24 Dec
Ameristar Casino Resort and Spa

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
26.6 km from Southwest Garden
8.8 out of 10, Excellent, (1016)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is ฿3,837
฿4,410 total
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites by Hilton St. Louis St. Charles

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
26.1 km from Southwest Garden
8.0 out of 10, Very good, (1005)
"The room is decent for a night. The price is great and hotel staff is friendly. "
United States
Jordan
The price is ฿2,776
฿3,219 total
includes taxes & fees
28 Dec - 29 Dec
Best Western Plus The Charles Hotel

Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South
2.5 star property
15.7 km from Southwest Garden
9.6 out of 10, Exceptional, (327)
"nice spot right off the interstate."
United States
Jeffrey
The price is ฿3,646
฿4,193 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis South

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 7.9 km from Southwest Garden
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is ฿5,308
฿6,207 total
includes taxes & fees
23 Dec - 24 Dec
Missouri Athletic Club

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
12.6 km from Southwest Garden
8.4 out of 10, Very good, (1372)
"Excellent staff , location was great but the breakfast wasn’t very good"
United States
Christian
The price is ฿2,954
฿3,455 total
includes taxes & fees
28 Dec - 29 Dec
Best Western St. Louis-Kirkwood Route 66

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 16.2 km from Southwest Garden
8.8 out of 10, Excellent, (1002)
"Clean room and very helpful staff"
United States
Amy
The price is ฿3,711
฿4,313 total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 7.5 km from Southwest Garden
9.0 out of 10, Wonderful, (1003)
"Was a great stay. "
United States
Lorilyn
The price is ฿3,043
฿3,620 total
includes taxes & fees
20 Jan - 21 Jan 2026
Courtyard by Marriott St. Louis Downtown/Convention Center

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 6.2 km from Southwest Garden
8.6 out of 10, Excellent, (1006)
"The hotel itself was just beautiful and grand! Beautifully decorated for the holidays and the amenities and attractions surrounding Union station were perfect for our family of 4! Our room was spacious and clean and we loved our stay! "
United States
Kelly
The price is ฿4,919
฿5,850 total
includes taxes & fees
4 Jan - 5 Jan 2026
St. Louis Union Station Hotel, Curio Collection by Hilton

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West, 7.1 km from Southwest Garden
8.0 out of 10, Very good, (609)
"Great stay "
United States
Kevin
The price is ฿2,447
฿2,861 total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton St. Louis Downtown

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
25.8 km from Southwest Garden
9.4 out of 10, Exceptional, (1003)
"Good stay."
United States
Steven
The price is ฿3,652
฿4,197 total
includes taxes & fees
18 Jan - 19 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 7.7 km from Southwest Garden
8.8 out of 10, Excellent, (1245)
"Great hospitality"
United States
Alejandro
The price is ฿3,451
฿4,104 total
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites by Hilton St. Louis Downtown

Marriott St. Louis West

Marriott St. Louis West
3.5 star property
19.7 km from Southwest Garden
8.6 out of 10, Excellent, (1001)
"Needs to fix the heat "
United States
Falah
The price is ฿4,245
฿4,934 total
includes taxes & fees
28 Dec - 29 Dec
Marriott St. Louis West

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West, 5.9 km from Southwest Garden
9.2 out of 10, Wonderful, (1006)
"Breakfast menu was fresh and tasty. Will return in the future with more time to go to the national park!"
United States
Silvar
The price is ฿3,361
฿4,010 total
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott St. Louis Downtown

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station
3.0 star property
Downtown West, 6 km from Southwest Garden
9.4 out of 10, Exceptional, (1302)
"Nice hotel"
United States
Vivian
The price is ฿3,737
฿4,445 total
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites St. Louis Union Station

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
20.8 km from Southwest Garden
8.4 out of 10, Very good, (1633)
"Great stay!"
United States
Ambrose
The price is ฿1,879
฿2,297 total
includes taxes & fees
4 Jan - 5 Jan 2026
Motel 6 Hazelwood, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southwest Garden

Find the best Southwest Garden areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Southwest Garden Hotel Reviews

Frequently asked questions

What is Southwest Garden like?
Travellers to St. Louis's Southwest Garden neighbourhood will be sure to enjoy a stay here.
How many hotels will I find in the Southwest Garden area?
Expedia has 30 hotels and other accommodation options in Southwest Garden to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Southwest Garden, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best options available in Southwest Garden.
What can I see and do in this St. Louis neighbourhood?
A few places to visit in the area around Southwest Garden include George Washington Carver Garden, Tower Grove Tennis Center and Missouri Botanical Gardens and Arboretum. While you're out sightseeing in St. Louis, make sure that you visit other sights such as St. Louis Science Center or Jewel Box.