Photo by Southernmost Illinois Tourism Bureau
Find hotels in Southern Illinois, IL from ฿1,561
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southern Illinois
Check prices for these dates
Our top choices for Southern Illinois hotels

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1008)
The price is ฿2,796
฿3,103 total
includes taxes & fees
1 Feb - 2 Feb

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1001)
The price is ฿2,757
฿3,087 total
includes taxes & fees
25 Jan - 26 Jan

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1000)
The price is ฿2,929
฿3,280 total
includes taxes & fees
1 Feb - 2 Feb

Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very good, (1008)
The price is ฿2,396
฿2,660 total
includes taxes & fees
1 Feb - 2 Feb

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1612)
The price is ฿3,463
฿3,905 total
includes taxes & fees
15 Jan - 16 Jan

Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (815)
The price is ฿2,130
฿2,322 total
includes taxes & fees
9 Jan - 10 Jan

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51Vandalia
8.4 out of 10, Very good, (1000)
The price is ฿2,005
฿2,185 total
includes taxes & fees
18 Jan - 19 Jan

Comfort Suites Effingham Central
Comfort Suites Effingham CentralEffingham
8.8 out of 10, Excellent, (581)
The price is ฿2,982
฿3,340 total
includes taxes & fees
1 Feb - 2 Feb

Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1002)
The price is ฿2,636
฿2,952 total
includes taxes & fees
3 Feb - 4 Feb

Super 8 by Wyndham Carbondale
Super 8 by Wyndham CarbondaleCarbondale
7.4 out of 10, Good, (1001)
The price is ฿1,880
฿2,161 total
includes taxes & fees
12 Jan - 13 Jan

Innkeeper Motel
Innkeeper MotelHamel
7.0 out of 10, Good, (2)
The price is ฿1,517
฿1,684 total
includes taxes & fees
8 Feb - 9 Feb

Holiday Inn Express & Suites Vandalia by IHG
Holiday Inn Express & Suites Vandalia by IHGVandalia
8.8 out of 10, Excellent, (783)
The price is ฿3,477
฿3,789 total
includes taxes & fees
25 Jan - 26 Jan

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (699)
The price is ฿3,314
฿3,678 total
includes taxes & fees
16 Jan - 17 Jan

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1001)
The price is ฿2,036
฿2,443 total
includes taxes & fees
22 Jan - 23 Jan

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (658)
The price is ฿3,276
฿3,668 total
includes taxes & fees
21 Jan - 22 Jan

Ramada by Wyndham Effingham
Ramada by Wyndham EffinghamEffingham
7.6 out of 10, Good, (1004)
The price is ฿1,678
฿1,878 total
includes taxes & fees
8 Feb - 9 Feb

Best Western Heartland Inn
Best Western Heartland InnMattoon
8.2 out of 10, Very good, (556)
The price is ฿2,263
฿2,534 total
includes taxes & fees
11 Jan - 12 Jan

Eighteen-Ninety Sleepover
Eighteen-Ninety SleepoverCasey
9.6 out of 10, Exceptional, (319)
The price is ฿3,790
฿4,245 total
includes taxes & fees
12 Jan - 13 Jan

Best Western Marion Hotel
Best Western Marion HotelMarion
8.2 out of 10, Very good, (1007)
The price is ฿2,209
฿2,650 total
includes taxes & fees
17 Jan - 18 Jan

Comfort Suites Mattoon East
Comfort Suites Mattoon EastMattoon
8.8 out of 10, Excellent, (889)
The price is ฿2,600
฿2,912 total
includes taxes & fees
25 Jan - 26 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southern Illinois, IL
Showing deals for:16 Jan - 18 Jan
Image gallery for Red Bud Country Inn

Red Bud Country Inn
Red Bud
9.0/10Wonderful (52 reviews)
25% off
Price is ฿2,004
฿4,447 total
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southern Illinois attractions
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews

Red Lion Inn & Suites Pontoon Beach
10/10 Excellent

Budget Motel Granite City/St Louis Area
10/10 Excellent
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ฿1,358 per night from 19 Jan to 20 Jan
฿1,358
฿1,561 total
19 Jan - 20 Jan
includes taxes & fees
7/10 Good! (1,009 reviews)













































































