Photo by Southernmost Illinois Tourism Bureau

Find hotels in Southern Illinois, IL from ฿1,725

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Our top choices for Southern Illinois hotels

Free daily self-service breakfast
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (513)
Located near Parkview Park and Town Square, this hotel offers a refreshing indoor pool and complimentary hot breakfast each morning. Enjoy the convenience of free WiFi and parking while the attentive staff ensures a pleasant stay for business and leisure travellers alike.
"Room was clean and amenities are fantastic. My family will certainly make this our top hotel choice in the area."
United States
Christian
The price is ฿3,499
฿3,883 total
includes taxes & fees
8 Jan - 9 Jan
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Lobby
SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (916)
This business-friendly hotel offers a peaceful base for exploring Southern Illinois. Wake up to continental breakfast before heading to nearby Pheasant Hollow Winery or hiking trails. Clean rooms, comfortable beds, and helpful staff ensure a pleasant, value-packed experience.
"Great place to stay."
United States
Stephen
The price is ฿2,269
฿2,519 total
includes taxes & fees
11 Jan - 12 Jan
SureStay Hotel by Best Western Whittington Rend Lake
Studio Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, rollaway beds
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale
2.0 star property
Carbondale
7.4 out of 10, Good, (1009)
Peaceful and business-friendly motel with complimentary WiFi, parking, and breakfast. Located close to African American Museum of Southern Illinois, with helpful staff ready to assist. Clean rooms provide comfort after exploring nearby attractions.
"Absolutely amazing staff , very professional and friendly and helpful. Clean rooms and good breakfast. Clean environment."
United States
Jerry
The price is ฿1,891
฿2,175 total
includes taxes & fees
5 Jan - 6 Jan
Super 8 by Wyndham Carbondale
Terrace/patio
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1011)
"It's great for travelers!"
United States
Kerry
The price is ฿3,546
฿3,999 total
includes taxes & fees
1 Feb - 2 Feb
Comfort Suites Mount Vernon
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Larger Room) | Pillow-top beds, desk, laptop workspace, blackout curtains
Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1002)
This Mascoutah hotel offers a refreshing indoor pool and fitness centre to keep your routine on track. Free parking, airport shuttle, and breakfast add value while clean rooms provide relaxation after exploring nearby Shiloh-Scott Station.
"Clean rooms, bed slept well, and a good breakfast."
United States
Kathryn
The price is ฿3,453
฿3,936 total
includes taxes & fees
7 Jan - 8 Jan
Best Western Plus MidAmerica Hotel
Lobby
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1005)
Modern hotel just 4 minutes from Williamson County Regional Airport. Take a morning dip in the indoor pool or unwind in the hot tub after exploring Marion Stadium. Enjoy complimentary WiFi, parking, and breakfast before heading to Kokopelli Golf Club.
"It was good hotel when we traveled "
United States
Olga
The price is ฿3,405
฿4,085 total
includes taxes & fees
18 Jan - 19 Jan
Comfort Inn & Suites Marion I-57
Seasonal outdoor pool, pool umbrellas, pool loungers
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very good, (1004)
Located near I-70 and Hwy 51, this quiet hotel offers free breakfast, WiFi and parking. The seasonal outdoor pool provides refreshing relaxation, while rooms include refrigerators and microwaves. Vandalia State House attractions are just moments away.
"Great staff, clean rooms"
United States
Hannah
The price is ฿2,010
฿2,190 total
includes taxes & fees
25 Jan - 26 Jan
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Suite, Accessible, Non Smoking | Blackout curtains, soundproofing, iron/ironing board, free WiFi
Laketree Inn And Suites Marion

Laketree Inn And Suites Marion

Laketree Inn And Suites Marion
2.0 star property
Marion
8.0 out of 10, Very good, (178)
Hike nearby Shawnee National Forest trails before returning to this welcoming hotel. With free WiFi and parking, plus a 24-hour front desk, convenience meets comfort. Goreville City Park and Lake of Egypt provide additional outdoor recreation options.
"Neat little Mom and Pop hotel on the edge of Shawnee National Forest. Very few perks, no breakfast or pool, but solid internet and there's a great BBQ place right down the road. We will be back."
United States
Sarah
The price is ฿2,522
฿2,798 total
includes taxes & fees
5 Jan - 6 Jan
Laketree Inn And Suites Marion
Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi
Best Western U. S. Inn

Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (395)
This quiet Nashville retreat offers a serene escape with free breakfast, WiFi, and parking. Swim in the outdoor pool after exploring nearby Nashville Memorial Park. Centralia Station is just 25 minutes away by car.
"Great and clean hotel"
United States
Jose
The price is ฿3,467
฿3,779 total
includes taxes & fees
5 Jan - 6 Jan
Best Western U. S. Inn
Lobby
Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (814)
Escape to this peaceful hotel where the helpful staff creates a welcoming atmosphere. Enjoy morning swims in the seasonal outdoor pool, workout in the fitness centre, and start each day with complimentary breakfast. Near Vandalia State House with free WiFi and parking.
"Very Clean, big bed. Would stay again, just know you definitely hear the highway all night."
United States
Amanda
The price is ฿2,144
฿2,336 total
includes taxes & fees
5 Jan - 6 Jan
Ramada by Wyndham Vandalia
Free daily buffet breakfast
Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1004)
Conveniently located near King City Square Shopping Centre, this welcoming hotel offers an indoor pool for morning swims and a 24-hour fitness centre. Guests praise the comfortable beds, helpful staff, and complimentary breakfast, WiFi, and parking.
"Second time staying here. Always easy and a good place to stay. Breakfast is good too. "
United States
Erik
The price is ฿3,121
฿3,527 total
includes taxes & fees
9 Jan - 10 Jan
Holiday Inn Express & Suites Mount Vernon by IHG
Indoor pool
Quality Inn Effingham North

Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.4 out of 10, Very good, (1007)
"Friendly staff, remodeled room."
United States
Nancy
The price is ฿2,412
฿2,676 total
includes taxes & fees
26 Jan - 27 Jan
Quality Inn Effingham North
Desk, iron/ironing board, free cots/infant beds, free rollaway beds
Super 8 by Wyndham Marion

Super 8 by Wyndham Marion

Super 8 by Wyndham Marion
2.0 star property
Marion
7.6 out of 10, Good, (1007)
Conveniently located just 4 minutes from Williamson County Regional Airport, this motel offers free breakfast, WiFi, and parking. Visit nearby Marion Stadium or Kokopelli Golf Club. Guests consistently praise the helpful staff and clean accommodation.
"Good hotel, clean, friendly, just off interstate with lots of food choices"
United States
Larry
The price is ฿2,049
฿2,459 total
includes taxes & fees
5 Jan - 6 Jan
Super 8 by Wyndham Marion
Lobby
Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area
2.5 star property
Carbondale
7.6 out of 10, Good, (520)
Enjoy the indoor pool and 24-hour fitness centre at this conveniently located hotel near Southern Illinois University. Just minutes from African American Museum and The Science Centre, guests praise the helpful staff. Free breakfast, WiFi and parking enhance your stay.
"Seemed a bit dated and needing fixed up in areas."
United States
Brandon
The price is ฿2,611
฿3,002 total
includes taxes & fees
18 Jan - 19 Jan
Comfort Inn & Suites Carbondale University Area
Lobby
Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL
2.0 star property
Troy
7.8 out of 10, Good, (1003)
Located minutes from Bella Vista and Villa Marie wineries, this Troy hotel offers an indoor pool for year-round swimming. Wake up to free continental breakfast and enjoy convenient amenities like WiFi and parking, all with attentive staff ready to assist.
"it was very good place to stay"
United States
Kent
The price is ฿2,142
฿2,377 total
includes taxes & fees
10 Jan - 11 Jan
Red Roof Inn St Louis - Troy, IL
Property entrance
Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.4 out of 10, Exceptional, (690)
"Very clean, nice hot breakfast, and kind staff. "
United States
Erin
The price is ฿3,335
฿3,701 total
includes taxes & fees
11 Jan - 12 Jan
Hampton Inn & Suites Effingham
Lobby
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1610)
Unwind in this quiet retreat featuring both indoor and outdoor pools, plus a hot tub. The 24-hour fitness centre keeps your routine on track while free breakfast energises your day. Convenient to restaurants, shops, and Veterans Memorial Park with helpful staff ready to assist.
"Clean nice people great place to stay"
United States
John
The price is ฿2,963
฿3,351 total
includes taxes & fees
11 Jan - 12 Jan
Drury Plaza Hotel Mt. Vernon
Exterior detail
Cobblestone Hotel & Suites - Newton

Cobblestone Hotel & Suites - Newton

Cobblestone Hotel & Suites - Newton
2.5 star property
Newton
9.2 out of 10, Wonderful, (326)
Enjoy gaming at the casino or maintain your workout at the fitness centre. The bar invites you to unwind after a busy day exploring nearby Jasper County Museum. Guests rave about helpful staff and outstanding property condition.
"Clean, pet friendly, nice breakfast,nice bar area staff was helpful and friendly "
United States
LaVae
The price is ฿2,979
฿3,306 total
includes taxes & fees
5 Jan - 6 Jan
Cobblestone Hotel & Suites - Newton
Indoor pool
Best Western Troy Hotel

Best Western Troy Hotel

Best Western Troy Hotel
2.5 star property
Troy
8.2 out of 10, Very good, (923)
This hotel offers a quiet retreat with an indoor pool and 24-hour fitness centre. Guests praise the helpful staff and clean rooms. Located near Bella Vista Winery, with free parking and WiFi for a comfortable, serene experience.
"Rooms were as expected and clean. "
United States
Adrienne
The price is ฿2,667
฿2,960 total
includes taxes & fees
7 Jan - 8 Jan
Best Western Troy Hotel
Gastropub
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

Baymont by Wyndham Effingham
2.5 star property
Effingham
8.0 out of 10, Very good, (1003)
Enjoy the 24-hour fitness centre and dine at RainTree Restaurant serving American cuisine for dinner. This Effingham hotel offers free breakfast, WiFi, and parking near Lake Sara and Cross at the Crossroads. Guests praise the helpful staff and clean rooms.
"Clean rooms, toiletries available, great breakfast and friendly staff!"
United States
Angela
The price is ฿2,385
฿2,647 total
includes taxes & fees
10 Jan - 11 Jan
Baymont by Wyndham Effingham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Holiday Rentals in Southern Illinois

Cottage
House (3 Bedrooms) | Interior
Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg Home w/ Private Yard + Screened Porch!
3.0 star property
Harrisburg
10.0 out of 10, Exceptional, (1)
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Harrisburg Home w/ Private Yard + Screened Porch!
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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

4.8/5 (32 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties

Harrah's Metropolis

4.0/5 (164 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards programme to maximise your experience while enjoying Southern classics at the on-site restaurants.
See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois
Southern Illinois featuring landscape views, a sunset and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

10/10 Excellent
"Amazing hotel. Price is fare. Renovated, clean spacious, friendly staff, well organized. Would recommend!!!! Thank You so much!!!! "
Oleksandr 1-night trip
Posted 4 days ago
Red Lion Inn & Suites Pontoon Beach

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
The price is ฿1,501 per night from 11 Jan to 12 Jan
฿1,501
฿1,725 total
11 Jan - 12 Jan
includes taxes & fees
7/10 Good! (1,007 reviews)