Photo by Southernmost Illinois Tourism Bureau
Find hotels in Southern Illinois, IL from ฿1,938
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southern Illinois
Pet friendly
Check prices for these dates
Our top choices for Southern Illinois hotels
Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,663 reviews)
"Beautiful hotel and loved the kickback and breakfast."
Lori
The price is ฿3,585
฿4,044 total
includes taxes & fees
3 May - 4 May
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,007 reviews)
"Clean room, comfy beds, easy and friendly check in. "
Renee
The price is ฿2,793
฿3,099 total
includes taxes & fees
12 Apr - 13 Apr
Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay!"
Tiffany
The price is ฿3,683
฿4,152 total
includes taxes & fees
19 Apr - 20 Apr
La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,002 reviews)
" Very pleased with our stay
"
Nancy
The price is ฿3,158
฿3,536 total
includes taxes & fees
19 Apr - 20 Apr
Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,007 reviews)
"Lovely hotel with exceptionally nice staff and clean and great room!"
Eileen
The price is ฿3,424
฿4,108 total
includes taxes & fees
20 Apr - 21 Apr
Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,024 reviews)
"Clean room, friendly staff, great rate, and great amenities. Would definitely stay again"
Lisa
The price is ฿3,641
฿4,106 total
includes taxes & fees
12 Apr - 13 Apr
Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1,009 reviews)
"Great staff, clean room, and good breakfast!"
Gayle
The price is ฿2,911
฿3,260 total
includes taxes & fees
3 May - 4 May
Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (726 reviews)
"Nice place"
Corey
The price is ฿4,477
฿4,968 total
includes taxes & fees
19 Apr - 20 Apr
Home2 Suites By Hilton Effingham
Home2 Suites By Hilton EffinghamEffingham
9.8 out of 10, Exceptional, (40 reviews)
"Great stay"
William
The price is ฿4,479
฿5,016 total
includes taxes & fees
3 May - 4 May
The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (228 reviews)
"I love staying here whenever i come to town."
bonnie
The price is ฿3,644
฿4,044 total
includes taxes & fees
12 Apr - 13 Apr
Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (671 reviews)
"easy arrival, nice room"
Susan
The price is ฿3,133
฿3,509 total
includes taxes & fees
19 Apr - 20 Apr
SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (944 reviews)
"We were looking for a hotel close to Pheasant Hollow Winery in order to attend one of their special events. We hit the jackpot with SureStay... it is only a couple minutes from the winery and is very clean, quiet and apparently efficiently run. We will definitely use in the future. "
Randall
The price is ฿2,762
฿3,065 total
includes taxes & fees
6 May - 7 May
Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (999 reviews)
"Great staff. "
Michael
The price is ฿3,618
฿4,051 total
includes taxes & fees
3 May - 4 May
Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (832 reviews)
"Room was clean and comfortable. "
Kevn
The price is ฿3,198
฿3,453 total
includes taxes & fees
29 Apr - 30 Apr
Walker's Bluff Casino Resort
Walker's Bluff Casino ResortCarterville
9.4 out of 10, Exceptional, (424 reviews)
"Great place!"
Paula
The price is ฿4,198
฿4,659 total
includes taxes & fees
14 Apr - 15 Apr
Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,002 reviews)
"Very nice hotel!"
Dawn
The price is ฿3,836
฿4,603 total
includes taxes & fees
12 Apr - 13 Apr
Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.0 out of 10, Very good, (1,000 reviews)
"The staff were very friendly! The room we stayed was clean, this is a very nice hotel especially for a single, overnight stay, with a great price! "
Adrenetta
The price is ฿2,197
฿2,438 total
includes taxes & fees
3 May - 4 May
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview HeightsFairview Heights
9.2 out of 10, Wonderful, (1,011 reviews)
"Staff was very welcoming and friendly. Breakfast was very good. Room was clean and comfortable. Excellent motel for the price. "
MEDFORD
The price is ฿3,295
฿3,722 total
includes taxes & fees
6 May - 7 May
Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (826 reviews)
"room to park truck and trailer, walmart close by"
Mike
The price is ฿2,197
฿2,394 total
includes taxes & fees
19 Apr - 20 Apr
Charleston House Bed & Breakfast Inn
Charleston House Bed & Breakfast InnCharleston
10.0 out of 10, Exceptional, (3 reviews)
"Beautifully restored property. Clean and comfortable room, bed, and linens.
Wonderful, delicious breakfast prepared and served by the friendly proprietor."
peter
The price is ฿3,071
฿3,408 total
includes taxes & fees
21 Apr - 22 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Super 8 by Wyndham Troy IL/St. Louis Area
10/10 Excellent
More cheap stays in Southern Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ฿1,717 per night from 16 Apr to 17 Apr
฿1,717
฿1,975 total
16 Apr - 17 Apr
includes taxes & fees
6.8/10 (1,001 reviews)
