Find hotels in Southeast Missouri, MO from ฿1,833
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,007 reviews)
"Great place!"
Jennifer
The price is ฿3,682
฿4,234 total
includes taxes & fees
12 Jul - 13 Jul
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,013 reviews)
"Wonderful room and food offerings were extra thoughtful."
Jonna
The price is ฿3,649
฿4,117 total
includes taxes & fees
26 Jul - 27 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (794 reviews)
"Beautiful hotel at a very good price."
Sheldon
The price is ฿3,074
฿3,327 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Staff and breakfast were excellent."
James
The price is ฿3,649
฿4,117 total
includes taxes & fees
30 Jul - 31 Jul
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (929 reviews)
"Hotel Staff was very friendly!"
Alice
The price is ฿3,483
฿3,935 total
includes taxes & fees
3 Aug - 4 Aug
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (587 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
Brandi
The price is ฿3,509
฿3,973 total
includes taxes & fees
23 Jul - 24 Jul
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,007 reviews)
"Great hotel"
mason
The price is ฿2,388
฿2,694 total
includes taxes & fees
2 Aug - 3 Aug
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,003 reviews)
"Clean room and convenient location."
Morgan
The price is ฿2,621
฿2,935 total
includes taxes & fees
8 Jul - 9 Jul
Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
7.2 out of 10, Good, (404 reviews)
"Owner was very kind. He knew we were running a long trail race the next morning and got up an hour early so he could make coffee and put out breakfast for us at 5:30 am. We were so grateful!"
Julie
The price is ฿1,932
฿2,110 total
includes taxes & fees
20 Jul - 21 Jul
Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (305 reviews)
"Rooms were clean! Beds were comfortable, and the staff were very accommodating."
Ashley
The price is ฿2,903
฿3,171 total
includes taxes & fees
15 Jul - 16 Jul
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
William
The price is ฿2,762
฿2,920 total
includes taxes & fees
26 Jul - 27 Jul
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (371 reviews)
"Simple no frills hotel that we've stayed at a few times while traveling."
Monica
The price is ฿3,314
฿3,593 total
includes taxes & fees
8 Jul - 9 Jul
Deerfield Inn & Suites Steele Near Blytheville I 55
Deerfield Inn & Suites Steele Near Blytheville I 55Steele
8.8 out of 10, Excellent, (3 reviews)
"Love it, very peaceful! What else want from me"
Mary
The price is ฿1,601
฿1,853 total
includes taxes & fees
9 Jul - 10 Jul
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (474 reviews)
"Only stayed one night, no complaints"
Zachary
The price is ฿3,483
฿3,944 total
includes taxes & fees
26 Jul - 27 Jul
Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.4 out of 10, Exceptional, (319 reviews)
"Breakfast was good and rooms were clean"
Shannon
The price is ฿4,091
฿4,468 total
includes taxes & fees
10 Jul - 11 Jul
Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (185 reviews)
"This was the cutest little place to stay. The people are friendly, room was clean, and it was safe. I would stay here again. "
Jennifer
The price is ฿3,613
฿3,910 total
includes taxes & fees
8 Jul - 9 Jul
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,003 reviews)
"Clean room, check in was easy. It was a good stopover for 1 night."
Nancy
The price is ฿2,792
฿3,192 total
includes taxes & fees
15 Jul - 16 Jul
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (573 reviews)
"Rooms are very clean. Easy and fast check in"
Kanyia
The price is ฿2,679
฿3,047 total
includes taxes & fees
18 Jul - 19 Jul
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (641 reviews)
"Excellent staff and location was nice and quiet
"
Colleen
The price is ฿3,638
฿3,960 total
includes taxes & fees
1 Aug - 2 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (206 reviews)
"The room was clean, the staff was extremely helpful with our check in!"
Travis
The price is ฿3,074
฿3,468 total
includes taxes & fees
2 Aug - 3 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (82 reviews)
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Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to Walnut Hollow Lake.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ฿2,183 per night from 21 Jul to 22 Jul
฿2,183
฿2,376 total
21 Jul - 22 Jul
includes taxes & fees
8/10 Very good! (1,012 reviews)
