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Search Hotels in South Mission Beach, San Diego

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23 Dec - 24 Dec
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24 Dec - 25 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for South Mission Beach hotels

City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 9.5 km from South Mission Beach
9.0 out of 10, Wonderful, (132)
"Great place to stay "
United States
Jacorey
The price is ฿4,111
฿4,767 total
includes taxes & fees
7 Jan - 8 Jan 2026
Courtyard by Marriott San Diego Downtown Little Italy
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.1 km from South Mission Beach
8.4 out of 10, Very good, (6049)
"Always an amazing stay"
United States
Jana
The price is ฿4,206
฿5,780 total
includes taxes & fees
25 Dec - 26 Dec
Wyndham San Diego Bayside
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.7 km from South Mission Beach
8.8 out of 10, Excellent, (1307)
"Checking in was easy and friendly staff."
United States
Elvira
The price is ฿2,768
฿3,181 total
includes taxes & fees
20 Jan - 21 Jan 2026
Hampton Inn San Diego/Mission Valley
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 1.5 km from South Mission Beach
9.0 out of 10, Wonderful, (3936)
"Always love staying here. Staff was very courteous and the rooms very clean. "
United States
Eric
The price is ฿4,326
฿5,595 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Dana on Mission Bay
Outdoor pool, pool umbrellas, pool loungers
Handlery Hotel

Handlery Hotel

Handlery Hotel
3.5 star property
7.6 km from South Mission Beach
8.2 out of 10, Very good, (2244)
"Room and staff were excellent"
United States
Bryant
Handlery Hotel
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 19.1 km from South Mission Beach
8.4 out of 10, Very good, (1916)
"Excellent location"
United States
Paolo
The price is ฿3,065
฿3,492 total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from South Mission Beach
9.0 out of 10, Wonderful, (3173)
"Nice hotel"
United States
Genelle
The price is ฿5,294
฿7,569 total
includes taxes & fees
25 Dec - 26 Dec
Hard Rock Hotel San Diego
Deluxe Room, 2 Queen Beds | Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 10 km from South Mission Beach
9.0 out of 10, Wonderful, (2882)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is ฿4,700
฿7,145 total
includes taxes & fees
24 Dec - 25 Dec
Manchester Grand Hyatt San Diego
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 10.9 km from South Mission Beach
9.2 out of 10, Wonderful, (2051)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is ฿6,059
฿8,432 total
includes taxes & fees
24 Dec - 25 Dec
Omni San Diego Hotel at the Ballpark
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
7.3 km from South Mission Beach
8.8 out of 10, Excellent, (3581)
"Clean and the amenities were outstanding, the staff was polite and helpful 👍 "
United States
walter
Kings Inn San Diego
BBQ/picnic Area
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
6.6 km from South Mission Beach
9.2 out of 10, Wonderful, (1044)
"Excellent staff,breakfast,transportation "
United States
Weldon
The price is ฿4,233
฿4,865 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express San Diego Airport - Old Town by IHG
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
8 km from South Mission Beach
8.0 out of 10, Very good, (2436)
"Clean room and excellent service "
United States
Jaime
The price is ฿2,619
฿3,011 total
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, pool loungers
Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego, 5.7 km from South Mission Beach
8.4 out of 10, Very good, (1871)
"Excellent location, courteous staff, great airport shuttle, delicious on-site restaurant."
United States
Kathleen
The price is ฿3,614
฿4,154 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Hacienda Hotel Old Town
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
7.8 km from South Mission Beach
9.2 out of 10, Wonderful, (2949)
"Clean room, friendly staff, beautiful property "
United States
roxanne
The price is ฿4,736
฿5,443 total
includes taxes & fees
4 Jan - 5 Jan 2026
Legacy Resort Hotel & Spa
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
6.1 km from South Mission Beach
9.2 out of 10, Wonderful, (3216)
"Great stay and location!"
United States
Jason
The price is ฿3,614
฿4,154 total
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina
Daily buffet breakfast for a fee
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
8.8 km from South Mission Beach
8.4 out of 10, Very good, (1422)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is ฿3,496
฿4,019 total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley
Front of property
The Sofia Hotel

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from South Mission Beach
8.4 out of 10, Very good, (1663)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel
Terrace/patio
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
6.6 km from South Mission Beach
8.8 out of 10, Excellent, (1317)
"Great rooms, breakfast was convenient. "
United States
Melissa
The price is ฿3,803
฿4,371 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
Reception
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
4.6 km from South Mission Beach
9.2 out of 10, Wonderful, (433)
"Clean rooms, friendly staff."
United States
KARLA
The price is ฿3,148
฿3,619 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites by Hilton San Diego SeaWorld
Beach nearby, beach towels
Hampton Inn Cardiff Beach Encinitas, CA

Hampton Inn Cardiff Beach Encinitas, CA

Hampton Inn Cardiff Beach Encinitas, CA
3.0 star property
29.3 km from South Mission Beach
9.2 out of 10, Wonderful, (1047)
"Clean room and staff were excellent."
United States
Jose
The price is ฿3,803
฿4,183 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn Cardiff Beach Encinitas, CA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Mission Beach

Find the best South Mission Beach areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach Park showing a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top South Mission Beach Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"Clean room and friendly staff. Great views for the city. "
Marco 2-night trip
Posted 2 days ago
Courtyard by Marriott San Diego Downtown Little Italy

Frequently asked questions

What's it like in South Mission Beach?
Guests are sure to enjoy their time checking out all that San Diego's South Mission Beach neighbourhood has to offer. Looking for sights you might find in a travel guide about South Mission Beach? Consider a visit to Mission Bay while you're in the neighbourhood.
How many hotels are there in South Mission Beach?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 321 South Mission Beach hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Mission Beach, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best options available in South Mission Beach.
What is there to do in this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission Beach, Mission and Pacific Beaches and South Mission Beach while you're in South Mission Beach. You could also plan a visit to Mission Bay or Belmont Park while you're in the neighbourhood. Golf Gardens Miniature Golf, Dog Beach and Bahia Point Beach are just a few of the places to visit in and around South Mission Beach. While you're out sightseeing in San Diego, make sure that you visit other sights such as Ocean Beach Athletic Area or Ocean Beach.