A coastal town with a marina, residential buildings, and a bridge in the background.

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Check availability on Siesta Isle Gay-Friendly Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Siesta Isle LGBT-friendly hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,001 reviews)
"I like this hotel we have been twice"
United States
Giovanna
The price is ฿3,344
฿3,729 total
includes taxes & fees
2 Nov - 3 Nov
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

2. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
2.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is ฿3,412
฿3,804 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

3. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
2.6 km from Siesta Isle
8.8 out of 10, Excellent, (1,003 reviews)
"One of the best properties I’ve stayed in and the staff were excellent."
United States
Christina
The price is ฿3,296
฿3,675 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

4. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
2.3 km from Siesta Isle
8.2 out of 10, Very good, (1,398 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is ฿2,891
฿3,224 total
includes taxes & fees
9 Nov - 10 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

5. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,002 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is ฿3,175
฿3,540 total
includes taxes & fees
15 Nov - 16 Nov
Residence Inn by Marriott Fort Myers Sanibel
A boat named 'Carolina Daze' with a covered seating area, a steering wheel, and a view of a waterway with greenery and buildings in the background.

6. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,002 reviews)
"Great place to stay, especially on a fishing trip!"
United States
Mitchel
The price is ฿3,156
฿3,519 total
includes taxes & fees
2 Nov - 3 Nov
Latitude 26 Waterfront Resort & Marina
A balcony with wicker furniture, a view of a beach, and a clear sky.

7. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (2,165 reviews)
"It was great to be right on the beach! The restaurants were also good."
United States
Tanya
The price is ฿3,803
฿4,994 total
includes taxes & fees
2 Nov - 3 Nov
Lani Kai Beachfront Resort
A hotel entrance with a sign reading 'Candlewood Suites' and a parking lot with a handicapped parking space.

8. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
4.9 km from Siesta Isle
7.6 out of 10, Good, (1,003 reviews)
"I was satisfied with the price for a short stay."
United States
James
The price is ฿2,567
฿2,862 total
includes taxes & fees
8 Nov - 9 Nov
Candlewood Suites Fort Myers Sanibel Gateway by IHG
An outdoor patio with a barbecue area, seating, and string lights.

9. Homewood Suites by Hilton Fort Myers Airport/FGCU

Homewood Suites by Hilton Fort Myers Airport/FGCU
3.0 star property
17 km from Siesta Isle
9.4 out of 10, Exceptional, (1,000 reviews)
"Great property good location friendly staff very clean room good breakfast"
United States
Leo
The price is ฿4,163
฿4,642 total
includes taxes & fees
22 Nov - 23 Nov
Homewood Suites by Hilton Fort Myers Airport/FGCU
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

10. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
5.7 km from Siesta Isle
8.6 out of 10, Excellent, (1,001 reviews)
"I love everything about this hotel"
United States
Yunior
The price is ฿6,999
฿8,986 total
includes taxes & fees
15 Nov - 16 Nov
Marriott Sanibel Harbour Resort & Spa
A shower with a glass door, a toilet, and a towel rack with folded towels.

11. SpringHill Suites by Marriott Fort Myers Airport

SpringHill Suites by Marriott Fort Myers Airport
3.0 star property
17.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Airport transfers are great and a very helpful staff. Clean room and good breakfast."
United States
Maria
The price is ฿2,986
฿3,329 total
includes taxes & fees
29 Nov - 30 Nov
SpringHill Suites by Marriott Fort Myers Airport
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.7 km from Siesta Isle
9.4 out of 10, Exceptional, (1,736 reviews)
"Excellent hotel if you want to stay there for a few days"
United States
Gabriel
The price is ฿3,378
฿3,766 total
includes taxes & fees
10 Nov - 11 Nov
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

13. Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
18.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,164 reviews)
"The breakfast was amazing"
United States
Erika
The price is ฿2,512
฿2,801 total
includes taxes & fees
30 Nov - 1 Dec
Comfort Inn & Suites Fort Myers Airport
A Drury Inn & Suites hotel with a parking lot full of cars.

14. Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
4.0 star property
16.5 km from Siesta Isle
9.6 out of 10, Exceptional, (1,003 reviews)
"clean nice location breakfast nice"
United States
Giselia Dos Santos
The price is ฿4,019
฿4,481 total
includes taxes & fees
1 Dec - 2 Dec
Drury Inn & Suites Fort Myers Airport FGCU
A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

15. Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
12.1 km from Siesta Isle
9.0 out of 10, Wonderful, (1,197 reviews)
"Clean, affordable, good location for what we needed, restaurants in walking distance."
United States
James
The price is ฿3,704
฿4,130 total
includes taxes & fees
23 Nov - 24 Nov
Doubletree by Hilton Fort Myers at Bell Tower Shops
Lobby lounge

16. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
11.1 km from Siesta Isle
8.8 out of 10, Excellent, (939 reviews)
"Friendly staff, very clean, very good breakfast and great location near restaurants and stores."
United States
Beatrice
The price is ฿2,675
฿2,983 total
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
A spacious lobby with a modern design, featuring a central seating area with a red sofa and multiple red ottomans, surrounded by large potted plants and a circular light fixture.

17. Hilton Garden Inn Fort Myers Airport/FGCU

Hilton Garden Inn Fort Myers Airport/FGCU
3.0 star property
17.1 km from Siesta Isle
8.8 out of 10, Excellent, (1,002 reviews)
"Shuttle to the airport was excellent, restaurant food while limited was well presented and the staff all very pleasant"
United States
Daniel
The price is ฿3,991
฿4,450 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Garden Inn Fort Myers Airport/FGCU
A balcony with a table and chairs, large windows, and a view of the sea.

18. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
8.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,003 reviews)
"Very clean and nice place!"
United States
Charles
The price is ฿4,941
฿7,016 total
includes taxes & fees
15 Nov - 16 Nov
The Westin Cape Coral Resort At Marina Village
A poolside area with outdoor seating, a fire pit, and a building with multiple balconies.

19. Courtyard by Marriott Fort Myers I-75/Gulf Coast Town Center

Courtyard by Marriott Fort Myers I-75/Gulf Coast Town Center
3.0 star property
16.5 km from Siesta Isle
9.2 out of 10, Wonderful, (618 reviews)
"Nice place to stay."
United States
Juan Carlos
The price is ฿4,020
฿4,482 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard by Marriott Fort Myers I-75/Gulf Coast Town Center
A spacious lobby with a reception desk, seating area, and a large window providing a view of the outdoors.

20. Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG
4.0 star property
16.4 km from Siesta Isle
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean property nice staff plesant stay"
Canada
Cristina
The price is ฿5,438
฿6,064 total
includes taxes & fees
29 Nov - 30 Nov
Crowne Plaza Ft. Myers Gulf Coast by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Siesta Isle Hotel Reviews

Frequently asked questions

Looking for gay-friendly accommodation in Siesta Isle?
Book a place where you can be yourself! You'll find gay-friendly hotels in Siesta Isle on Expedia. Discover the people, places and traditions found only in Siesta Isle.
What is the favourite LGBTQ-friendly place to stay in Siesta Isle?
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is a top LGBTQ-friendly hotel, and features a marina and free WiFi.
What are the top places to visit in Siesta Isle?
During your trip, get out and enjoy everything Siesta Isle has to offer. You and your travelling companions may want to visit San Carlos Bay - Bunche Beach Preserve. While you're here, capture some great memories of your trip with a stop at Key West Express.
What is a gay-friendly hotel in Siesta Isle?
LGBTQ-friendly hotels welcome all travellers who identify as LGBTQIA+. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Siesta Isle, hotels affiliated with IGLTA operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from an LGBTQ-friendly Siesta Isle hotel?
Stay at a gay-friendly hotel in Siesta Isle and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer community-specific packages, exclusive tours and opportunities for social interaction.