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Check prices for these dates

This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

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Our top choices for Santo Domingo hotels

A hotel with a swimming pool surrounded by potted plants and a clear blue sky.

1. Villas Del Sol Hotel

Villas Del Sol Hotel
3.5 star property
10.1 km from Santo Domingo
7.8 out of 10, Good, (270 reviews)
"Friendly and helpful staff, clean, nice property"
Canada
Christine
The price is ฿1,452
฿1,728 total
includes taxes & fees
3 Oct - 4 Oct
Villas Del Sol Hotel
A modern bedroom with a bed, a chair, a nightstand, and a starry sky mural on the ceiling.

2. Life Hotel

Life Hotel
3.5 star property
12.7 km from Santo Domingo
8.8 out of 10, Excellent, (268 reviews)
"Great value, friendly staff, convenient location"
Canada
Orly
The price is ฿1,865
฿2,219 total
includes taxes & fees
3 Oct - 4 Oct
Life Hotel
A pool area with lounge chairs and a pergola.

3. Casa Bonita Hotel & Luxury Residence

Casa Bonita Hotel & Luxury Residence
4.0 star property
13.3 km from Santo Domingo
8.8 out of 10, Excellent, (272 reviews)
"Love the room love the food,loved the taxi services loved the plac"
United States
jimmy william
The price is ฿3,533
฿4,204 total
includes taxes & fees
30 Sept - 1 Oct
Casa Bonita Hotel & Luxury Residence
A poolside table with pastries, a cup of coffee, and a decorative tablecloth.

4. Hotel San Felipe

Hotel San Felipe
4.0 star property
13.5 km from Santo Domingo
9.0 out of 10, Wonderful, (19 reviews)
"Kink of fur from el centro, other than that good place to stay "
United States
Alfredo
The price is ฿2,165
฿2,577 total
includes taxes & fees
30 Sept - 1 Oct
Hotel San Felipe
An outdoor dining area with a city view, wooden flooring, and modern furniture.

5. Flavia Hotel

Flavia Hotel
3.0 star property
12.4 km from Santo Domingo
9.0 out of 10, Wonderful, (110 reviews)
"The most beautiful properties I’ve ever stayed up. There’s no reason to leave the resort. Everything you need is here. Very clean, the food is good, I loved the pool pools, the gym and the exercise room! And the actual hotel room was just amazing. The staff was also very kind and friendly. I highly recommend."
United States
Tanya
The price is ฿5,575
฿6,634 total
includes taxes & fees
30 Sept - 1 Oct
Flavia Hotel
A covered outdoor seating area with lounge chairs, a large potted plant, and hanging lanterns.

6. Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
13.7 km from Santo Domingo
9.2 out of 10, Wonderful, (220 reviews)
"From the check in to the breakfast. staff was very attentive to all our needs from tours to the hotel amenities"
United States
Desiderio
The price is ฿5,956
฿7,088 total
includes taxes & fees
2 Oct - 3 Oct
Casa de Adobe Gallery & Luxury Boutique
A couple in a hot tub with a decorative tiled wall in the background.

7. Los Olivos Spa

Los Olivos Spa
3.0 star property
13.7 km from Santo Domingo
8.4 out of 10, Very good, (203 reviews)
"I love the SPA and the personal is excelent"
United States
Ekizabeth
The price is ฿2,095
฿2,494 total
includes taxes & fees
1 Oct - 2 Oct
Los Olivos Spa
A hotel room with two beds, a desk, a television, and a minibar.

8. Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG
3.0 star property
15.2 km from Santo Domingo
9.6 out of 10, Exceptional, (1,004 reviews)
"Clean room, breakfast buffet offered, parking convenient and location is walking distance to historic center and restaurants"
United States
Tito
The price is ฿3,914
฿4,658 total
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express Oaxaca-Centro Historico by IHG
A poolside area with lounge chairs and umbrellas, a covered seating area, and a pool.

9. Fiesta Inn Oaxaca

Fiesta Inn Oaxaca
3.5 star property
18.9 km from Santo Domingo
8.8 out of 10, Excellent, (1,008 reviews)
"good hotel"
United States
JORGE
The price is ฿3,456
฿4,112 total
includes taxes & fees
5 Oct - 6 Oct
Fiesta Inn Oaxaca
A poolside setting with a wooden bridge, a book, a lime half, sunglasses, and a plate of sliced vegetables.

10. Hotel Fortin Plaza

Hotel Fortin Plaza
3.5 star property
14.7 km from Santo Domingo
8.8 out of 10, Excellent, (1,012 reviews)
"Everything was excellent at Hotel Fortin Plaza"
United States
Alberto
The price is ฿2,525
฿3,005 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Fortin Plaza
A courtyard with a central building featuring a dome and arches, surrounded by stone buildings.

11. Quinta Real Oaxaca

Quinta Real Oaxaca
4.5 star property
15.8 km from Santo Domingo
9.6 out of 10, Exceptional, (1,001 reviews)
"Great hotel if you like old world charm."
United States
William
The price is ฿10,713
฿12,749 total
includes taxes & fees
18 Oct - 19 Oct
Quinta Real Oaxaca
A dining area with a table set for six, overlooking a cityscape with mountains in the distance.

12. Casa Acueducto

Casa Acueducto
4.0 star property
14.4 km from Santo Domingo
9.6 out of 10, Exceptional, (52 reviews)
"I loved where i"
United States
Brenda
The price is ฿1,430
฿1,702 total
includes taxes & fees
30 Sept - 1 Oct
Casa Acueducto
A modern building with a prominent 'One' sign, potted plants, and a curved entrance.

13. One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
16.2 km from Santo Domingo
8.8 out of 10, Excellent, (1,008 reviews)
"Clean room, close to restaurant"
United States
Jorge
The price is ฿2,352
฿2,799 total
includes taxes & fees
19 Oct - 20 Oct
One Oaxaca Centro Hotel
A spacious courtyard with columns, outdoor seating, and potted plants.

14. Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
16.2 km from Santo Domingo
9.4 out of 10, Exceptional, (1,008 reviews)
"Well located, with wonderful staff."
United States
Jean
The price is ฿3,441
฿4,095 total
includes taxes & fees
1 Oct - 2 Oct
Hotel Boutique Naura Centro
An outdoor patio with steps leading to a seating area, surrounded by a low wall and a tree.

15. City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
15.9 km from Santo Domingo
9.0 out of 10, Wonderful, (845 reviews)
"staff was great"
United States
Fredy
The price is ฿4,844
฿5,764 total
includes taxes & fees
11 Oct - 12 Oct
City Centro by Marriott Oaxaca
A spacious lobby with a spiral staircase, a chandelier, and a reception desk.

16. Hotel Trebol

Hotel Trebol
3.0 star property
16.2 km from Santo Domingo
9.2 out of 10, Wonderful, (1,006 reviews)
"Excellent location, great accommodation, and lovely helpful staff."
United States
Ariadna
The price is ฿2,796
฿3,327 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Trebol
A hotel room with a bed, a desk with a sink, a chair, a television, and a window with curtains.

17. City Express by Marriott Oaxaca

City Express by Marriott Oaxaca
3.0 star property
14.9 km from Santo Domingo
8.6 out of 10, Excellent, (861 reviews)
"My sisters, cousins and I stayed here in August 2026 for a girls trip and had a wonderful experience. A huge highlight was the breakfast buffet which was fresh and had plenty of options. The location is perfect a few minutes from Downtown and surrounded by good local restaurants."
United States
Cristina
The price is ฿2,524
฿3,003 total
includes taxes & fees
18 Oct - 19 Oct
City Express by Marriott Oaxaca
A rooftop pool area with a swimming pool, outdoor seating, and a building with a red dome and a cross on top.

18. Hotel Hacienda

Hotel Hacienda
3.5 star property
17.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1,006 reviews)
"Staff was very friendly and helpful. I will stay there again."
United States
Martin
The price is ฿2,070
฿2,463 total
includes taxes & fees
1 Oct - 2 Oct
Hotel Hacienda
A multi-level hotel with a central courtyard, featuring balconies, a dining area, and a staircase.

19. Hotel Danibaan

Hotel Danibaan
3.0 star property
15.2 km from Santo Domingo
9.4 out of 10, Exceptional, (216 reviews)
"Excelente hotel "
Mexico
Alejandra
The price is ฿1,696
฿2,018 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Danibaan
A poolside area with lounge chairs, a flower arrangement, and palm trees.

20. Hotel Victoria Oaxaca

Hotel Victoria Oaxaca
3.5 star property
14.6 km from Santo Domingo
8.8 out of 10, Excellent, (1,018 reviews)
"Hotel familiar"
Mexico
Sergio
The price is ฿2,189
฿2,605 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Victoria Oaxaca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santo Domingo Hotel Reviews

Hotel Hacienda

Hotel Hacienda

8/10 Good
"Like the property"
Maria 5-night trip
Posted 3 hours ago
Hotel Hacienda

Frequently asked questions

What's it like in Santo Domingo?
Travellers will be sure to find plenty to entertain them in Villa de Etla's Santo Domingo neighbourhood.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Santo Domingo.
What is there to do in this Villa de Etla neighbourhood?
Places you might want to visit in the area around Santo Domingo include Parroquia de San Pedro y San Pablo Etla and Balneario Las Brisas. You could also plan a stop at San Pablo Trailhead when you're sightseeing around the area.