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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Santo Domingo hotels

A hotel with a swimming pool surrounded by potted plants and a clear blue sky.

1. Villas Del Sol Hotel

Villas Del Sol Hotel
3.5 star property
10.1 km from Santo Domingo
7.8 out of 10, Good, (271 reviews)
"Friendly and helpful staff, clean, nice property"
Canada
Christine
The price is ฿1,604
฿1,908 total
includes taxes & fees
24 Oct - 25 Oct
Villas Del Sol Hotel
A modern bedroom with a bed, a chair, a nightstand, and a starry sky mural on the ceiling.

2. Life Hotel

Life Hotel
3.5 star property
12.7 km from Santo Domingo
8.8 out of 10, Excellent, (269 reviews)
"Great value, friendly staff, convenient location"
Canada
Orly
The price is ฿2,343
฿2,788 total
includes taxes & fees
18 Oct - 19 Oct
Life Hotel
An outdoor dining area with a city view, wooden flooring, and modern furniture.

3. Flavia Hotel

Flavia Hotel
3.0 star property
12.4 km from Santo Domingo
9.0 out of 10, Wonderful, (110 reviews)
"The most beautiful properties I’ve ever stayed up. There’s no reason to leave the resort. Everything you need is here. Very clean, the food is good, I loved the pool pools, the gym and the exercise room! And the actual hotel room was just amazing. The staff was also very kind and friendly. I highly recommend."
United States
Tanya
The price is ฿5,709
฿6,793 total
includes taxes & fees
20 Oct - 21 Oct
Flavia Hotel
A pool area with lounge chairs and a pergola.

4. Casa Bonita Hotel & Luxury Residence

Casa Bonita Hotel & Luxury Residence
4.0 star property
13.3 km from Santo Domingo
8.8 out of 10, Excellent, (272 reviews)
"Love the room love the food,loved the taxi services loved the plac"
United States
jimmy william
The price is ฿6,145
฿7,312 total
includes taxes & fees
18 Oct - 19 Oct
Casa Bonita Hotel & Luxury Residence
A pool area with a clear blue pool, surrounded by lush greenery and a building with multiple balconies.

5. Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
13.7 km from Santo Domingo
9.2 out of 10, Wonderful, (220 reviews)
"From the check in to the breakfast. staff was very attentive to all our needs from tours to the hotel amenities"
United States
Desiderio
The price is ฿4,166
฿4,958 total
includes taxes & fees
18 Oct - 19 Oct
Casa de Adobe Gallery & Luxury Boutique
A couple in a hot tub with a decorative tiled wall in the background.

6. Los Olivos Spa

Los Olivos Spa
3.0 star property
13.7 km from Santo Domingo
8.4 out of 10, Very good, (204 reviews)
"I love the SPA and the personal is excelent"
United States
Ekizabeth
The price is ฿2,151
฿2,560 total
includes taxes & fees
3 Nov - 4 Nov
Los Olivos Spa
A hotel room with two beds, a desk, a television, and a minibar.

7. Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG
3.0 star property
15.2 km from Santo Domingo
9.6 out of 10, Exceptional, (1,003 reviews)
"Clean room, breakfast buffet offered, parking convenient and location is walking distance to historic center and restaurants"
United States
Tito
The price is ฿3,865
฿4,599 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express Oaxaca-Centro Historico by IHG
A poolside area with lounge chairs and umbrellas, a covered seating area, and a pool.

8. Fiesta Inn Oaxaca

Fiesta Inn Oaxaca
3.5 star property
18.9 km from Santo Domingo
8.8 out of 10, Excellent, (1,005 reviews)
"good hotel"
United States
JORGE
The price is ฿3,860
฿4,594 total
includes taxes & fees
17 Oct - 18 Oct
Fiesta Inn Oaxaca
A poolside area with lounge chairs, a flower arrangement, and palm trees.

9. Hotel Victoria Oaxaca

Hotel Victoria Oaxaca
3.5 star property
14.6 km from Santo Domingo
8.8 out of 10, Excellent, (1,019 reviews)
"I liked the way the staff was very attentive and helpful. The room was very clean. The Zocalo and Mercado were just a few minutes away and the hotel had a shuttle that took you to the centro. I would definitely recommend it."
United States
Renato
The price is ฿2,131
฿2,536 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Victoria Oaxaca
A modern building with a prominent 'One' sign, potted plants, and a curved entrance.

10. One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
16.2 km from Santo Domingo
8.8 out of 10, Excellent, (1,001 reviews)
"Clean room, close to restaurant"
United States
Jorge
The price is ฿2,825
฿3,362 total
includes taxes & fees
18 Oct - 19 Oct
One Oaxaca Centro Hotel
A corridor with a yellow wall, a chandelier, potted plants, and a bench.

11. Hotel Doña Alicia

Hotel Doña Alicia
3.0 star property
15.6 km from Santo Domingo
8.8 out of 10, Excellent, (79 reviews)
"Very comfortable place to stay for a few days."
United States
Wayne
The price is ฿1,514
฿1,802 total
includes taxes & fees
7 Nov - 8 Nov
Hotel Doña Alicia
An outdoor patio with tables and chairs, umbrellas, and a variety of plants.

12. Happy Express Hotel

Happy Express Hotel
2.5 star property
15.9 km from Santo Domingo
9.0 out of 10, Wonderful, (406 reviews)
"Staff were attentive and nice. It rained during our stay and when we got out of the taxi the receptionist ran to give us a umbrella. The room was quiet and clean. They give you bottled water which was a plus. Close to mercados and the zocalo which was a plus. Definitely will come again."
United States
jacqueline consuelo
The price is ฿1,680
฿2,000 total
includes taxes & fees
16 Oct - 17 Oct
Happy Express Hotel
A dining area with a table set for six, overlooking a cityscape with mountains in the distance.

13. Casa Acueducto

Casa Acueducto
4.0 star property
14.4 km from Santo Domingo
9.6 out of 10, Exceptional, (55 reviews)
"I loved where i"
United States
Brenda
The price is ฿1,872
฿2,227 total
includes taxes & fees
17 Oct - 18 Oct
Casa Acueducto
A hotel room with a bed, a desk with a sink, a chair, a television, and a window with curtains.

14. City Express by Marriott Oaxaca

City Express by Marriott Oaxaca
3.0 star property
14.9 km from Santo Domingo
8.6 out of 10, Excellent, (863 reviews)
"My sisters, cousins and I stayed here in August 2026 for a girls trip and had a wonderful experience. A huge highlight was the breakfast buffet which was fresh and had plenty of options. The location is perfect a few minutes from Downtown and surrounded by good local restaurants."
United States
Cristina
The price is ฿2,786
฿3,315 total
includes taxes & fees
18 Oct - 19 Oct
City Express by Marriott Oaxaca
A courtyard with a central building featuring a dome and arches, surrounded by stone buildings.

15. Quinta Real Oaxaca

Quinta Real Oaxaca
4.5 star property
15.8 km from Santo Domingo
9.6 out of 10, Exceptional, (1,001 reviews)
"Great hotel if you like old world charm."
United States
William
The price is ฿9,884
฿11,762 total
includes taxes & fees
8 Nov - 9 Nov
Quinta Real Oaxaca
A pool area with a large agave plant in the foreground, surrounded by a fence and various trees.

16. Villa Santa Julia

Villa Santa Julia
3.0 star property
14.4 km from Santo Domingo
9.6 out of 10, Exceptional, (33 reviews)
"Excellent gem of a find in the Reforma area of Oaxaca City. Great value, very secure, nice pool area, modern room and comfortable bed, walkable to lots of food options, and has private and secure parking. "
United States
Justin
The price is ฿2,552
฿3,037 total
includes taxes & fees
14 Nov - 15 Nov
Villa Santa Julia
An outdoor patio with steps leading to a seating area, surrounded by a low wall and a tree.

17. City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
15.9 km from Santo Domingo
8.8 out of 10, Excellent, (852 reviews)
"staff was great"
United States
Fredy
The price is ฿5,749
฿6,841 total
includes taxes & fees
18 Oct - 19 Oct
City Centro by Marriott Oaxaca
A spacious lobby with a spiral staircase, a chandelier, and a reception desk.

18. Hotel Trebol

Hotel Trebol
3.0 star property
16.2 km from Santo Domingo
9.2 out of 10, Wonderful, (1,007 reviews)
"Excellent location, great accommodation, and lovely helpful staff."
United States
Ariadna
The price is ฿3,057
฿3,638 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Trebol
A poolside setting with a wooden bridge, a book, a lime half, sunglasses, and a plate of sliced vegetables.

19. Hotel Fortin Plaza

Hotel Fortin Plaza
3.5 star property
14.7 km from Santo Domingo
8.8 out of 10, Excellent, (1,001 reviews)
"Everything was excellent at Hotel Fortin Plaza"
United States
Alberto
The price is ฿2,261
฿2,691 total
includes taxes & fees
20 Oct - 21 Oct
Hotel Fortin Plaza
A hotel lobby with a reception desk, a seating area, and a dining space.

20. Hotel Veracruz

Hotel Veracruz
3.0 star property
15.5 km from Santo Domingo
8.6 out of 10, Excellent, (199 reviews)
"Verry good place "
United States
Mariano
The price is ฿2,254
฿2,682 total
includes taxes & fees
16 Oct - 17 Oct
Hotel Veracruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Hotel Reviews

Hotel Hacienda

Hotel Hacienda

10/10 Excellent
"Very quaint hotel."
Norma 6-night trip
Posted 17 hours ago
Hotel Hacienda

Frequently asked questions

What's it like in Santo Domingo?
Travellers will be sure to find plenty to entertain them in Villa de Etla's Santo Domingo neighbourhood.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Santo Domingo.
What is there to do in this Villa de Etla neighbourhood?
Places you might want to visit in the area around Santo Domingo include Parroquia de San Pedro y San Pablo Etla and Balneario Las Brisas. You could also plan a stop at San Pablo Trailhead when you're sightseeing around the area.