Find hotels in Santa Maria from ฿1,289

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Check prices for these dates

Tonight
23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santa Maria hotels

Terrace/patio
Termas el Corazon

Termas el Corazon

Termas el Corazon
3.0 star property
Los Andes
7.2 out of 10, Good, (10)
"Perfect place to relax. Clean, quiet with great food and excellent service"
Canada
Jean-Luc
Termas el Corazon
Exterior detail
Inca Hoteles

Inca Hoteles

Inca Hoteles
3.5 star property
Los Andes
9.2 out of 10, Wonderful, (135)
"Restaurant and breakfast buffet are delicious! Rooms were perfect size and very clean. Staff is incredibly friendly and helpful. Easy drive to Portillo to ski! "
United States
CAMERON
The price is ฿3,424
฿3,424 total
17 Jan - 18 Jan 2026
Inca Hoteles
Front of property
Hotel Genova

Hotel Genova

Hotel Genova
2.5 star property
Los Andes
7.2 out of 10, Good, (39)
"The staff wasn’t very friendly Good place to stay."
United States
Jose
The price is ฿1,289
฿1,289 total
28 Dec - 29 Dec
Hotel Genova
Seasonal outdoor pool, pool umbrellas, pool loungers
Casona El Resguardo

Casona El Resguardo

Casona El Resguardo
3.0 star property
San Esteban
9.6 out of 10, Exceptional, (5)
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
United States
Anonymous traveller
The price is ฿4,313
฿4,313 total
20 Jan - 21 Jan 2026
Casona El Resguardo
Economy Twin Room
Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes
2.0 star property
San Felipe
9.4 out of 10, Exceptional, (3)
"Excelente "
Costa Rica
Anonymous traveller
The price is ฿2,210
฿2,210 total
30 Dec - 31 Dec
Hotel y Cabañas Palomar - Caja los Andes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Maria attractions

El Zaino Dreaming Stones

You can find out about the history of Santa Maria when you stop by El Zaino Dreaming Stones.
See properties

Top Santa Maria Hotel Reviews

Casona El Resguardo

Casona El Resguardo

10/10 Excellent
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
Anonymous traveller 3-night trip
Posted 4 months ago
Casona El Resguardo

More cheap stays in Santa Maria

Hotel Genova

Hotel Genova

523 Las Heras Los Andes Región de Valparaíso
The price is ฿1,289 per night from 28 Dec to 29 Dec
฿1,289
฿1,289 total
28 Dec - 29 Dec
7.2/10 Good! (39 reviews)

Frequently asked questions

Where is the best place to stay in Santa Maria?
Based on our traveller data, Termas Jahuel Hotel & Spa is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Two other options for your stay in the area are Termas el Corazon and Hotel Genova. See all available top hotels, or vacation rentals in Santa Maria.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Maria.
What's the best accommodation for an all-inclusive stay in Santa Maria?
Termas Jahuel Hotel & Spa is an all-inclusive hotel featuring a full-service spa and a health club, and a favourite with Expedia travellers. See more all-inclusive resorts in Santa Maria.
What is staying in Santa Maria like?
Travellers to Santa Maria will find plenty to explore and enjoy. There are 23 hotels and other accommodation options in the surrounding area. Find out more about Santa Maria.
What is there to see in Santa Maria?
A favourite place to visit is El Zaino Dreaming Stones. You'll also find Termas El Corazón and Museo Antiguo Monasterio del Espíritu Santo in the area. Take a look at what more there is to see and do in Expedia's Santa Maria guide.
What's the seasonal weather like in Santa Maria?
The hottest months are usually January and February, with an average temperature of 20°C, while the coldest months are July and June, with an average of 10°C. Average annual precipitation for Santa Maria is 365 mm.