Find hotels in Santa Isabel from ฿1,052

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 Santa Isabel hotels and places to stay

Our top choices for Santa Isabel hotels

Hotel Araiza Mexicali

4.0 star property
8.6 out of 10, Excellent, (1540)
"Great place to vacay "
The price is ฿2,852
฿3,223 total
includes taxes & fees
31 Aug - 1 Sept
Hotel Araiza Mexicali

Real Inn Mexicali

4.0 star property
8.2 out of 10, Very good, (1429)
"Great place "
The price is ฿2,424
฿2,739 total
includes taxes & fees
31 Aug - 1 Sept
Real Inn Mexicali

One Mexicali

3.0 star property
7.8 out of 10, Good, (1004)
"Clean and close to restaurants. "
The price is ฿1,884
฿2,129 total
includes taxes & fees
26 Aug - 27 Aug
One Mexicali

Hotel Siesta Real

3.0 star property
8.2 out of 10, Very good, (815)
"Loved resturant on-site. Wish it was open for dinner. Will stay again! Comfy beds "
The price is ฿2,384
฿2,694 total
includes taxes & fees
26 Aug - 27 Aug
Hotel Siesta Real

Holiday Inn Express & Suites Mexicali by IHG

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Great hotel, location and service"
The price is ฿3,828
฿4,325 total
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Express & Suites Mexicali by IHG

Hotel Lucerna Mexicali

4.0 star property
9.2 out of 10, Wonderful, (1325)
"Great Hotel, in my opinion the best in Mexicali. "
The price is ฿3,255
฿3,678 total
includes taxes & fees
7 Sept - 8 Sept
Hotel Lucerna Mexicali

City Express Plus by Marriott Mexicali

3.5 star property
8.6 out of 10, Excellent, (842)
"Excellent place to stay. Very clean and comfortable. "
The price is ฿2,858
฿3,230 total
includes taxes & fees
31 Aug - 1 Sept
City Express Plus by Marriott Mexicali

Azteca de Oro Mexicali

3.0 star property
7.4 out of 10, Good, (375)
"👍"
The price is ฿1,116
฿1,261 total
includes taxes & fees
26 Aug - 27 Aug
Azteca de Oro Mexicali

Calafia Hotel

3.5 star property
8.2 out of 10, Very good, (1004)
"Good hotel"
The price is ฿2,433
฿2,749 total
includes taxes & fees
26 Aug - 27 Aug
Calafia Hotel

City Express by Marriott Mexicali

3.0 star property
8.2 out of 10, Very good, (1003)
"Staff was very welcoming and attentive "
The price is ฿2,684
฿3,033 total
includes taxes & fees
20 Sept - 21 Sept
City Express by Marriott Mexicali

Extended Suites Mexicali Cataviña

3.0 star property
8.0 out of 10, Very good, (2062)
"Affordable and great location "
Extended Suites Mexicali Cataviña

Fairfield Inn & Suites by Marriott Mexicali

2.5 star property
9.4 out of 10, Exceptional, (1004)
"Enjoyed our stay."
The price is ฿3,273
฿3,699 total
includes taxes & fees
5 Sept - 6 Sept
Fairfield Inn & Suites by Marriott Mexicali

Fiesta Inn Mexicali

3.5 star property
8.2 out of 10, Very good, (1002)
"Had a nice stay "
The price is ฿2,593
฿2,930 total
includes taxes & fees
29 Aug - 30 Aug
Fiesta Inn Mexicali

City Express Junior by Marriott Mexicali

3.0 star property
7.8 out of 10, Good, (1001)
"- staff accommodated my needs friendly friendly and place was quiet enough to relax "
The price is ฿2,091
฿2,363 total
includes taxes & fees
5 Sept - 6 Sept
City Express Junior by Marriott Mexicali

Motel Cies

3.0 star property
9.2 out of 10, Wonderful, (45)
"Great place to stay awesome service "
The price is ฿1,726
฿1,985 total
includes taxes & fees
26 Aug - 27 Aug
Motel Cies

Hotel Colonial Mexicali

3.5 star property
7.8 out of 10, Good, (1003)
"It was affordable, the room was clean and in great condition"
Hotel Colonial Mexicali

Courtyard by Marriott Mexicali

3.0 star property
9.4 out of 10, Exceptional, (738)
"This hotel is clean, comfortable and a great location. The staff is friendly and welcoming "
The price is ฿3,370
฿3,809 total
includes taxes & fees
29 Aug - 30 Aug
Courtyard by Marriott Mexicali

Hotel Cosmos Don Carlos

3.0 star property
8.0 out of 10, Very good, (458)
"Location is great "
Hotel Cosmos Don Carlos

HOTEL DON QUIJOTE

2.0 star property
6.6 out of 10, (12)
"Entrance/exit driveway difficult to negotiate."
The price is ฿1,052
฿1,272 total
includes taxes & fees
28 Aug - 29 Aug
HOTEL DON QUIJOTE

Hotel Regis

3.0 star property
7.2 out of 10, Good, (111)
"Perfect "
Hotel Regis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Accommodation near Santa Isabel attractions

Plaza Comercial La Cachanilla

Plaza Comercial La Cachanilla

You can do some window-shopping at Plaza Comercial La Cachanilla during your stay in Mexicali. While you're here, you can savour the top-notch restaurants.

Learn more about Santa Isabel

Venture to Gran Plaza Outlets and Mexicali Border Port I—just two of the sights around Santa Isabel.

Top Santa Isabel Hotel Reviews

Frequently asked questions

What's the best place for a stay in Santa Isabel?

Hotel Lucerna Mexicali, located 7.5 mi (12.1 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel Araiza Mexicali and Real Inn Mexicali. See all available top hotels, or vacation rentals in Santa Isabel.

If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.

What is staying in Santa Isabel like?

Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 73 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.

What is there to see in Santa Isabel?

Places to visit in the wider area include Gran Plaza Outlets, Mexicali Border Port I and Plaza Comercial La Cachanilla. You'll also find Eagles Nest Stadium and Imperial Valley Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.

What's the seasonal weather like in Santa Isabel?

The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. Average annual precipitation for Santa Isabel is 84 mm.