Default HTG hotel image

Find hotels in Santa Isabel from ฿1,302

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Filter by

Star rating

Guest rating

Our top choices for Santa Isabel hotels

A modern lounge area with sofas, round tables, and pendant lighting.
A modern bar area with a pool table, bar stools, and a burger on the counter.
A spacious indoor area with a central seating area, a reception desk, and a large window providing natural light.
A modern hotel room with a large bed, a desk, a chair, a bathroom with a sink and mirror, and a view of the city through large windows.

1. City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali
Mexicali
United States
MANUEL
฿3,248
฿3,671 total
includes taxes & fees
16 Oct - 17 Oct
City Express Plus by Marriott Mexicali
A modern kitchen with a large island, bar stools, pendant lighting, and a staircase leading to an upper level.
A modern living room with a sofa, coffee table, and shelves with decorative items.
A swimming pool with two umbrellas, lounge chairs, and potted plants.
A modern building with a stone facade, large windows, and a covered entrance area.

2. Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali
Mexicali
United States
Blanca
฿3,688
฿4,168 total
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites by Marriott Mexicali
A bar area with seating, a bar counter, and a wall-mounted screen.
A hotel with a modern facade, a prominent logo, and a well-lit entrance.
A dining table with a variety of dishes including a steak, salad, and a dessert. There are also two drinks on the table.
A modern hotel room with a large bed, a wooden headboard, a flat-screen TV, and a painting on the wall.

3. Hotel Araiza Mexicali

Hotel Araiza Mexicali
Mexicali
United States
Talisa
฿3,932
฿4,443 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Araiza Mexicali
A hand holding a blue drink with ice cubes, a swimming pool, palm trees, and a hotel building in the background.
A corridor with stone sculptures on the walls, a tiled floor, and a sign indicating restrooms.
An indoor area with wicker furniture, a stone planter with rocks, and a bar area with a counter.
An outdoor patio area with tables and chairs, surrounded by palm trees and potted plants.

4. Hotel Lucerna Mexicali

Hotel Lucerna Mexicali
Mexicali
United States
Luis
฿3,659
฿4,135 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Lucerna Mexicali
A modern outdoor seating area with wicker furniture, potted plants, and a wooden deck.
A brightly lit kitchen area with a green wall, a sign for Desayuno Express, and a tiled backsplash.
A modern living room with a sofa, armchairs, a coffee table, and a decorative wall piece.
A modern kitchen with a central island, bar stools, wooden cabinets, stainless steel appliances, and pendant lighting.

5. Holiday Inn Express & Suites Mexicali by IHG

Holiday Inn Express & Suites Mexicali by IHG
Mexicali
United States
Aleyda
฿4,097
฿4,629 total
includes taxes & fees
16 Oct - 17 Oct
Holiday Inn Express & Suites Mexicali by IHG
A modern hotel lobby with a green and orange color scheme, multiple seating areas, and digital kiosks displaying hotel information.
A modern hotel with a prominent 'one' sign, a stone facade, and a parking area with vehicles.
A hotel room with two beds, a desk with a laptop, a TV mounted on the wall, and a window with a city view.
A reception area with a blue wall, a wooden reception desk, a digital screen, and a refrigerator.

6. One Mexicali

One Mexicali
Mexicali
United States
francisco
฿2,347
฿2,652 total
includes taxes & fees
12 Oct - 13 Oct
One Mexicali
A breakfast table set with plates of food, glasses of orange juice, and a basket of pastries.
A person sitting on a bed with a glass of orange juice, a plate of fruit, and a magazine.
A modern office space with cubicles, computers, and a view of a green wall.
A laptop on a desk with a cup, a lamp, and a chair, overlooking a hilly landscape.

7. Fiesta Inn Mexicali

Fiesta Inn Mexicali
Civic Center
United States
Adolfo
฿2,734
฿3,090 total
includes taxes & fees
18 Oct - 19 Oct
Fiesta Inn Mexicali
A buffet area with various food dispensers, a coffee machine, and a salad bar.
A hotel reception area with two reception desks, a large painting on the wall, and a mezzanine level.
A modern lounge area with grey sofas, a flat-screen TV mounted on a wooden panel, and a large window offering a view of the outside.
A modern lounge area with a grey sofa, yellow ottoman, and a wooden coffee table. There are bar stools and a flat-screen TV mounted on a wooden wall.

8. City Express by Marriott Mexicali

City Express by Marriott Mexicali
Mexicali
United States
Paulina
฿2,521
฿2,849 total
includes taxes & fees
18 Oct - 19 Oct
City Express by Marriott Mexicali
A buffet area with various food items and a counter.
A multi-story building with balconies, a parking area, and palm trees.
A gym with treadmills, weight machines, and dumbbells.
A rooftop swimming pool with a glass enclosure, a covered seating area, and a building with a red-tiled roof.

9. Calafia Hotel

Calafia Hotel
Mexicali
United States
Heriberto
฿2,772
฿3,132 total
includes taxes & fees
18 Oct - 19 Oct
Calafia Hotel
A pool area with lounge chairs, a covered seating area, and palm trees.
A courtyard with a pathway, palm trees, and a building with multiple windows.
A tree with a hammock, a bench, and a building in the background.
A spacious restaurant with multiple tables and chairs, a bar area with a marble countertop, and a view of the outside through large windows.

10. Hotel Colonial Mexicali

Hotel Colonial Mexicali
Civic Center
United States
Martha
฿2,690
฿3,040 total
includes taxes & fees
14 Oct - 15 Oct
Hotel Colonial Mexicali
A rooftop lounge area with outdoor seating, large windows, and a view of the cityscape.
A hotel room with two beds, a desk, a chair, and a large window with curtains.
A modern hotel with a large sign reading "COURTYARD BY MARRIOTT". It features a clean, rectangular facade with evenly spaced windows and a flat roof.
A reception area with a wooden reception desk, two computer monitors, a sign reading "BONVAY," and a modern chandelier.

11. Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali
Mexicali
United States
Cecilia
฿4,104
฿4,638 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard by Marriott Mexicali
A refrigerated display case with various dairy products and beverages.
A compact kitchen with a white refrigerator, wooden cabinets, a built-in microwave, and a window with a view.
A swimming pool with a stone facade and multiple windows.
A multi-story hotel with a central entrance, multiple balconies, and a parking area with handicapped accessibility.

12. Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña
Mexicali
United States
Alisson
฿1,618
฿1,958 total
includes taxes & fees
12 Oct - 13 Oct
Extended Suites Mexicali Cataviña
A modern hotel lobby with a reception desk, a seating area with a sofa and coffee table, and artwork on the walls.
A conference room with rows of chairs, a table with a laptop, and a cityscape painting on the wall.
A multi-story hotel with a prominent sign, a flat roof, and a well-lit entrance.
A gym with treadmills, a mirrored wall, and a cityscape painting.

13. Sleep Inn Mexicali

Sleep Inn Mexicali
Mexicali
United States
Francisco
฿2,244
฿2,715 total
includes taxes & fees
18 Oct - 19 Oct
Sleep Inn Mexicali
A hotel room with a bed, a desk, a chair, a TV, and artwork on the walls.
A gym with treadmills, stationary bikes, and elliptical machines.
A modern bar area with a long counter and multiple stools, a kitchen with stainless steel appliances, and a seating area with sofas and a patterned rug.
A reception desk with a wooden finish and a marble base, a neon sign above, and a snack display to the right.

14. Holiday Inn Mexicali Centro Civico by IHG

Holiday Inn Mexicali Centro Civico by IHG
Civic Center
United States
Hector
฿2,697
฿3,264 total
includes taxes & fees
16 Oct - 17 Oct
Holiday Inn Mexicali Centro Civico by IHG
A courtyard with a central fountain, a building with a balcony, and a tree.
Two people toasting with drinks at a table with a view of greenery outside.
A poolside area with lounge chairs and a menu board in the background.
A courtyard with a central fountain, surrounded by a building with balconies and a car parked nearby.

15. Hotel Siesta Real

Hotel Siesta Real
Mexicali
United States
Saul
฿2,403
฿2,716 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Siesta Real
A modern dining area with a sofa, tables, and chairs.
A modern interior with seating areas, a bar, and a view of the outside.
A parking lot with a sign for 'CITY EXPRESS junior by Marriott.'
A hotel room with two beds, a TV, a desk, and a window with a city view.

16. City Express Junior by Marriott Mexicali

City Express Junior by Marriott Mexicali
Mexicali
United States
RICARDO
฿1,870
฿2,113 total
includes taxes & fees
25 Oct - 26 Oct
City Express Junior by Marriott Mexicali
A hotel with multiple floors, a restaurant, and a parking area.
A lobby with a glass door, a staircase, and a Christmas tree.
A hotel room with a bed, bedside tables, a ceiling fan, a TV, a wardrobe, and a mirror.
A hotel room with a ceiling fan, an air conditioning unit, a mirror, and a wooden cabinet.

17. Hotel del Norte

Hotel del Norte
Mexicali Historic Center
United States
Adam
฿1,630
฿2,105 total
includes taxes & fees
12 Oct - 13 Oct
Hotel del Norte
A restaurant with booths and tables, a kitchen in the background, and a ceiling fan.
A restaurant sign with the name 'RESTAURANTE AZTECA DE ORO' and a stylized eagle logo.
A hotel room with a bed, a desk with a mirror, a television, and a door labeled '103'.
A hotel reception area with a modern design, including a reception desk, wall clocks, and a sign for a new laundry service.

18. Azteca de Oro Mexicali

Azteca de Oro Mexicali
Mexicali
United States
Jaleah
฿1,152
฿1,302 total
includes taxes & fees
12 Oct - 13 Oct
Azteca de Oro Mexicali
A reception area with a counter, a blue wall, a potted plant, and a window with a view.
A bedroom with a bed, white nightstands, a red accent on the nightstands, a wall with a motivational quote, and a brown bedspread.
A hotel with a modern design, featuring a prominent entrance, a parking area, and a sign indicating amenities.
A hotel reception area with a blue wall, a reception desk, a small counter, a window with a view of buildings, and a display of pastries.

19. Hotel Boulevard Mexicali

Hotel Boulevard Mexicali
Mexicali
Mexico
Josue
฿1,399
฿1,581 total
includes taxes & fees
12 Oct - 13 Oct
Hotel Boulevard Mexicali
A hotel with a sign reading "Cosmos Hotel" and a price tag of $795.
A spacious hallway with a chandelier, a fireplace, and a staircase.
A staircase with a wooden handrail, a ceiling fan, and a door with a black gate.
A fountain with a mosaic border, a building entrance, and a tiled pavement.

20. Hotel Cosmos Don Carlos

Hotel Cosmos Don Carlos
Mexicali
United States
Leticia
฿1,573
฿1,777 total
includes taxes & fees
12 Oct - 13 Oct
Hotel Cosmos Don Carlos
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Isabel Hotel Reviews

City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali

10/10 Excellent
"Always the room is clean inviting love the are"
crystal 2-night trip
Posted 3 hours ago
City Express Plus by Marriott Mexicali
Holiday Inn Mexicali Centro Civico by IHG

Holiday Inn Mexicali Centro Civico by IHG

10/10 Excellent
"Good hotel"
Noe 1-night trip
Posted 17 hours ago
Holiday Inn Mexicali Centro Civico by IHG
Hotel del Norte

Hotel del Norte

10/10 Excellent
"The front desk staff were very helpful and the daily cleaning crew did an amazing job keeping my room tidey!"
David 4-night trip
Posted 19 hours ago
Hotel del Norte
Hotel Colonial Mexicali

Hotel Colonial Mexicali

10/10 Excellent
"Muy bien todo la estancia muy agradable"
marco Antonio 1-night trip
Posted 21 hours ago
Hotel Colonial Mexicali
Hotel Siesta Real

Hotel Siesta Real

10/10 Excellent
"Great location and stay good service"
Hector 1-night trip
Posted 22 hours ago
Hotel Siesta Real
Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali

10/10 Excellent
"great staff"
Ruben 2-night trip
Posted 2 days ago
Courtyard by Marriott Mexicali
Sleep Inn Mexicali

Sleep Inn Mexicali

10/10 Excellent
"I recommend this hotel nice and clean nice staff good location near shopping Center"
Francisco 2-night trip
Posted 2 days ago
Sleep Inn Mexicali

More cheap stays in Santa Isabel

Motel Las Fuentes

Motel Las Fuentes

Blvd Lopez Mateos 1655 Mexicali BC
฿1,252
฿1,540 total
12 Oct - 13 Oct
includes taxes & fees
Motel Las Fuentes
Hotel Misión Plaza Mexicali

Hotel Misión Plaza Mexicali

366 Av. Francisco I. Madero Mexicali BC
Get rates
7.2/10 Good! (54 reviews)
Hotel Misión Plaza Mexicali
HOTEL DON QUIJOTE

HOTEL DON QUIJOTE

Calz Independencia Independencia Mexicali BC
Get ratesHOTEL DON QUIJOTE
Motel Kiss

Motel Kiss

Carretera a Aeropuerto 4300 Mexicali BC
Get rates
7.8/10 Good! (179 reviews)
Motel Kiss
Motel Las Dunas

Motel Las Dunas

Calle Rio Culiacan s/n, Compuertas Mexicali BC
Get rates
7.6/10 Good! (38 reviews)
Motel Las Dunas
Casa Movil tipo estudio

Casa Movil tipo estudio

Sierra Sta Clara Sur Lomas de Abasolo Mexicali BC
Get ratesCasa Movil tipo estudio

Frequently asked questions

What's the best place for a stay in Santa Isabel?
Hotel Araiza Mexicali, located 7 mi (11.3 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel Lucerna Mexicali and Extended Suites Mexicali Cataviña. See all available top hotels, or vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 73 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What is there to see in Santa Isabel?
Places to visit in the wider area include Mexicali Border Port I, City Forest and Zoo and Plaza Comercial La Cachanilla. You'll also find Eagles Nest Stadium and Plaza San Pedro in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. Average annual precipitation for Santa Isabel is 84 mm.

Explore a world of travel with Expedia