Find hotels in Santa Isabel from ฿1,436

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Isabel hotels

Front of property

Motel Virreyes

Motel Virreyes
3.0 star property
Mexicali
10.0 out of 10, Exceptional, (6 reviews)
"I was good everything was nice and comfortable the staff was very good she was so nice the only thing was that there were not enough shampo conditioners 😅"
United States
Estefani
The price is ฿1,524
฿1,752 total
includes taxes & fees
1 Jun - 2 Jun
Motel Virreyes
Deluxe Suite, Jetted Tub | Laptop workspace, free WiFi, bed sheets

Motel Cies

Motel Cies
3.0 star property
Mexicali
9.2 out of 10, Wonderful, (63 reviews)
"Excellent place "
United States
Sandra
The price is ฿2,431
฿2,795 total
includes taxes & fees
27 May - 28 May
Motel Cies
Front of property – evening/night

Hotel del Norte

Hotel del Norte
3.0 star property
Mexicali Historic Center
8.4 out of 10, Very good, (1,002 reviews)
"The place is nice and convenient"
Mexico
Bruce
The price is ฿1,687
฿2,179 total
includes taxes & fees
8 Jun - 9 Jun
Hotel del Norte
Exterior

Motel Paraiso

Motel Paraiso
3.0 star property
Mexicali
9.6 out of 10, Exceptional, (5 reviews)
"Very Private and secure. I slept better than I do at home. Also a romantic setting"
United States
Joe
The price is ฿2,265
฿2,786 total
includes taxes & fees
1 Jun - 2 Jun
Motel Paraiso
Front of property

Hotel Cosmos Don Carlos

Hotel Cosmos Don Carlos
3.0 star property
Mexicali
8.0 out of 10, Very good, (533 reviews)
"It’s was great ; it’s is where we stay every time we go to Mexicali BC Mexico 🇲🇽 It’s close to a lot of places. I really like it there 👍"
Mexico
Virginia
The price is ฿1,342
฿1,516 total
includes taxes & fees
26 May - 27 May
Hotel Cosmos Don Carlos
Lobby

Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali
3.0 star property
Mexicali
9.6 out of 10, Exceptional, (1,008 reviews)
"Great hotel"
United States
Francisco
The price is ฿3,724
฿4,209 total
includes taxes & fees
30 May - 31 May
Fairfield Inn & Suites by Marriott Mexicali
Front of property

Motel Olimpo

Motel Olimpo
3.0 star property
Mexicali
7.6 out of 10, Good, (14 reviews)
"Fit my expectations, great stay"
United States
Yu
The price is ฿1,332
฿1,532 total
includes taxes & fees
1 Jun - 2 Jun
Motel Olimpo
Lobby

City Express Junior by Marriott Mexicali

City Express Junior by Marriott Mexicali
3.0 star property
Mexicali
8.0 out of 10, Very good, (1,001 reviews)
"The room was really clean it was a little small but comfortable the breakfast was amazing really fresh and tasty the staff was very nice and friendly "
United States
Nilsa
The price is ฿2,205
฿2,491 total
includes taxes & fees
27 May - 28 May
City Express Junior by Marriott Mexicali
Property amenity

Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (961 reviews)
"The hotel is in a very good location, breakfast is good but a little bit expensive"
United States
Anayel
The price is ฿3,764
฿4,253 total
includes taxes & fees
14 Jun - 15 Jun
Courtyard by Marriott Mexicali
Exterior

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali
4.0 star property
Mexicali
9.2 out of 10, Wonderful, (1,621 reviews)
"Clean rooms, awesome food and grwat staff"
United States
JOSE L
The price is ฿3,505
฿3,961 total
includes taxes & fees
31 May - 1 Jun
Hotel Lucerna Mexicali
Interior entrance

Sleep Inn Mexicali

Sleep Inn Mexicali
3.0 star property
Mexicali
8.2 out of 10, Very good, (1,001 reviews)
"Cool rooms , good staff, good breakfast "
United States
Alfonso
The price is ฿2,403
฿2,907 total
includes taxes & fees
27 May - 28 May
Sleep Inn Mexicali
Outdoor pool

Holiday Inn Express & Suites Mexicali by IHG

Holiday Inn Express & Suites Mexicali by IHG
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (1,002 reviews)
"The hotel location was perfect ! So many restaurants and shops around. The hotel itself was perfect! Staff was very friendly and our room was so nice."
United States
Aryanna
The price is ฿4,475
฿5,057 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express & Suites Mexicali by IHG
Outdoor pool

Calafia Hotel

Calafia Hotel
3.5 star property
Mexicali
8.4 out of 10, Very good, (1,004 reviews)
"Great place"
United States
Joshua
The price is ฿2,802
฿3,167 total
includes taxes & fees
26 May - 27 May
Calafia Hotel
Business centre

One Mexicali

One Mexicali
3.0 star property
Mexicali
8.0 out of 10, Very good, (1,003 reviews)
"Clean room and air conditioning with breakfast included what else can you want while staying close to all the fun places."
United States
james
The price is ฿2,483
฿2,806 total
includes taxes & fees
30 May - 31 May
One Mexicali
Lobby

City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali
3.5 star property
Mexicali
8.6 out of 10, Excellent, (1,004 reviews)
"Great price for great rooms, located in great area with a lot of places to go, staff really good and friendly"
United States
Alexandra
The price is ฿3,032
฿3,426 total
includes taxes & fees
31 May - 1 Jun
City Express Plus by Marriott Mexicali
Double Room | Soundproofing, free WiFi, bed sheets

Motel Diana

Motel Diana
3.0 star property
Mexicali
8.6 out of 10, Excellent, (12 reviews)
"Very small room, location is good but everything in the area is narrow down including street width Ok for its value but i won't book here again"
United States
Yu
The price is ฿1,285
฿1,478 total
includes taxes & fees
3 Jun - 4 Jun
Motel Diana
Exterior

Motel Kiss

Motel Kiss
2.5 star property
Mexicali
7.8 out of 10, Good, (179 reviews)
"Clean room great service "
United States
Ricardo
The price is ฿1,187
฿1,436 total
includes taxes & fees
31 May - 1 Jun
Motel Kiss
Outdoor banquet area

Hotel Araiza Mexicali

Hotel Araiza Mexicali
4.0 star property
Mexicali
8.8 out of 10, Excellent, (1,824 reviews)
"Helpful staff, the breakfast buffet was amazing!"
United States
Mario
The price is ฿3,787
฿4,280 total
includes taxes & fees
26 May - 27 May
Hotel Araiza Mexicali
TV

Hotel Colonial Mexicali

Hotel Colonial Mexicali
3.5 star property
Civic Center
8.0 out of 10, Very good, (1,004 reviews)
"Nice and quiet"
United States
Siugin
The price is ฿2,690
฿3,040 total
includes taxes & fees
26 May - 27 May
Hotel Colonial Mexicali
Interior

Hotel Siesta Real

Hotel Siesta Real
3.0 star property
Mexicali
8.2 out of 10, Very good, (1,006 reviews)
"Great location and clean rooms"
United States
Heriberto
The price is ฿2,564
฿2,898 total
includes taxes & fees
26 May - 27 May
Hotel Siesta Real
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Isabel Hotel Reviews

Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña

2/10 Terrible
"Check in was not bad, we reserved 2 rooms for 2 nights Second day we were told the pool was not in use due to chemicals being added. I asked front desk if there was a time frame of when we would be able to use, since we booked this hotel with the intention of using the pool, and the lady had no idea. She seemed bothered by my questions and did not seem to care or try to offer a solution/ option I later went back to front desk to ask if I could cancel my second night stay since the pool was unavailable and the lady said we have to figure it out with whoever we booked with. I ended up repacking up and getting a reservation at Hotel Colonial last minute. Now Extended Suites has refused to reimburse, reach out, or offer any assistance. They had bad customer service and attitude onsite so this doesn't surprise me. I understand things happen, but them running chemical or maintenance on not only a weekend, but a holiday weekend, just seems like it’s something that should’ve been communicated. I am not happy with this outcome. I will not be staying at or recommending this place to anyone."
Alondra 2-night trip
Posted 7 hours ago
Extended Suites Mexicali Cataviña

More cheap stays in Santa Isabel

Motel Kiss

Motel Kiss

Carretera a Aeropuerto 4300 Mexicali BC
The price is ฿1,187 per night from 31 May to 1 Jun
฿1,187
฿1,436 total
31 May - 1 Jun
includes taxes & fees
7.8/10 Good! (179 reviews)

Frequently asked questions

What's the best place for a stay in Santa Isabel?
Hotel Lucerna Mexicali, located 7.1 mi (11.5 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Real Inn Mexicali and Hotel Araiza Mexicali. See all available top hotels, or vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 72 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What is there to see in Santa Isabel?
Places to visit in the wider area include Mexicali Border Port I, Plaza Comercial La Cachanilla and Eagles Nest Stadium. You'll also find Plaza San Pedro and Imperial Valley Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. Average annual precipitation for Santa Isabel is 84 mm.