Find hotels in Santa Fe, FL from ฿1,755

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 Santa Fe hotels and places to stay

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (60)
"the cabin was amazing, great amenities i would recommend!!"
The price is ฿3,206
฿4,774 total
includes taxes & fees
29 Jul - 30 Jul
Postcard Cabins Gilchrist Springs

Drury Inn & Suites Gainesville

3.0 star property
9.6 out of 10, Exceptional, (1276)
"Overall really enjoyed the hotel."
The price is ฿3,400
฿3,825 total
includes taxes & fees
1 Aug - 2 Aug
Drury Inn & Suites Gainesville

Depot Village

2.0 star property
9.4 out of 10, Exceptional, (43)
"Such a unique set up & a block away from downtown - and an excellent staff!"
The price is ฿1,755
฿6,104 total
includes taxes & fees
3 Aug - 4 Aug
Depot Village

Best Western Waldo Inn and Suites

2.5 star property
8.8 out of 10, Excellent, (898)
"Very clean, comfortable and good breakfast. Staff very pleasant too."
The price is ฿3,303
฿3,716 total
includes taxes & fees
4 Aug - 5 Aug
Best Western Waldo Inn and Suites

Vista Verde Farm Retreat

2.0 star property
9.8 out of 10, Exceptional, (6)
"This is my second time staying on this property and I love it "
The price is ฿3,692
฿6,406 total
includes taxes & fees
29 Jul - 30 Jul
Vista Verde Farm Retreat

Hyatt Place Gainesville Downtown

3.0 star property
9.0 out of 10, Wonderful, (1019)
"Great service and comfortable rooms"
The price is ฿3,644
฿4,099 total
includes taxes & fees
30 Jul - 31 Jul
Hyatt Place Gainesville Downtown

Comfort Suites Gainesville near University

2.5 star property
9.2 out of 10, Wonderful, (1023)
"Always clean, very courteous staff. Great location for medical visits to Shands "
The price is ฿2,594
฿2,919 total
includes taxes & fees
3 Aug - 4 Aug
Comfort Suites Gainesville near University

Sleep Inn & Suites University/Shands

2.5 star property
8.6 out of 10, Excellent, (1021)
"The staff were so friendly , the breakfast was great and the room was very nice and comfy !"
The price is ฿2,607
฿3,115 total
includes taxes & fees
3 Aug - 4 Aug
Sleep Inn & Suites University/Shands

La Quinta by Wyndham Gainesville

3.0 star property
9.0 out of 10, Wonderful, (1008)
"Clean room, clean bed, clean linem, great food, quiet room friendly and pleasant staff"
The price is ฿3,221
฿3,624 total
includes taxes & fees
29 Jul - 30 Jul
La Quinta by Wyndham Gainesville

Hampton Inn & Suites Gainesville-Downtown

3.0 star property
8.6 out of 10, Excellent, (1010)
"very clean and hospitable"
The price is ฿2,925
฿3,290 total
includes taxes & fees
24 Aug - 25 Aug
Hampton Inn & Suites Gainesville-Downtown

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (550)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is ฿2,168
฿2,439 total
includes taxes & fees
29 Jul - 30 Jul
Palms Garden Inn

hom hotel + suites, Trademark Collection by Wyndham

2.5 star property
8.4 out of 10, Very good, (1716)
"Great place to stay"
The price is ฿2,533
฿2,849 total
includes taxes & fees
3 Aug - 4 Aug
hom hotel + suites, Trademark Collection by Wyndham

Aloft Gainesville University Area

3.0 star property
8.8 out of 10, Excellent, (1005)
"Great place to stay "
The price is ฿3,249
฿3,655 total
includes taxes & fees
10 Aug - 11 Aug
Aloft Gainesville University Area

Hampton Inn & Suites Alachua I-75

2.5 star property
9.4 out of 10, Exceptional, (432)
"We would definitely stay here again if we are ever in this area. "
The price is ฿3,596
฿4,046 total
includes taxes & fees
4 Aug - 5 Aug
Hampton Inn & Suites Alachua I-75

High Springs Country Inn

2.0 star property
7.6 out of 10, Good, (5)
"Ive had a stay at this price point with better arrangement such as breakfast included. However, for only one night it wasnt too bad. Room is too dark. Lighter colors in the room luke greish would make it look more cozy."
The price is ฿2,354
฿2,648 total
includes taxes & fees
30 Jul - 31 Jul
High Springs Country Inn

Sweetwater Branch Inn

3.5 star property
9.6 out of 10, Exceptional, (929)
"We really loved this place and will be back to stay again!"
The price is ฿4,178
฿4,700 total
includes taxes & fees
29 Jul - 30 Jul
Sweetwater Branch Inn

Hotel Indigo Gainesville-Celebration Pointe by IHG

3.5 star property
9.0 out of 10, Wonderful, (1011)
"Very easy to check in and a fantastic location "
The price is ฿3,012
฿3,389 total
includes taxes & fees
3 Aug - 4 Aug
Hotel Indigo Gainesville-Celebration Pointe by IHG

Country Inn & Suites by Radisson, Gainesville, FL

3.0 star property
9.0 out of 10, Wonderful, (1453)
"Great place to stay"
The price is ฿2,863
฿3,221 total
includes taxes & fees
3 Aug - 4 Aug
Country Inn & Suites by Radisson, Gainesville, FL

Fairfield Inn & Suites by Marriott Gainesville I-75

2.5 star property
9.6 out of 10, Exceptional, (1011)
"Great place to stay "
The price is ฿3,401
฿3,826 total
includes taxes & fees
31 Jul - 1 Aug
Fairfield Inn & Suites by Marriott Gainesville I-75

Holiday Inn Express & Suites Gainesville I-75 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Great stay"
The price is ฿3,692
฿4,154 total
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express & Suites Gainesville I-75 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Fe

Check out O'Leno State Park and San Felasco Hammock Preserve State Park—just a couple of the sights around Santa Fe.

Top Santa Fe Hotel Reviews

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.5 mi (29.8 km) from the heart of Santa Fe, hom hotel + suites, Trademark Collection by Wyndham is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hyatt Place Gainesville Downtown and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

What are some hotels with pools in Santa Fe?

Hom hotel + suites, Trademark Collection by Wyndham: Features free buffet breakfast, a pool and free self-parking. DoubleTree by Hilton Gainesville and Drury Inn & Suites Gainesville are two additional hotels that offer an on-site pool. View all hotels with pools in Santa Fe.

What is staying in Santa Fe like?

Travellers to Santa Fe will find plenty to explore and enjoy. There are 654 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.

What is there to see in Santa Fe?

Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Devil's Milhopper Geological State Park. You'll also find Gainesville Raceway and Poe Springs Park in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.

What's the weather like in Santa Fe?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.