A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.

Search Gay-Friendly Hotels in Santa Cruz

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Gay-Friendly Hotels

Our top choices for Santa Cruz LGBT-friendly hotels

A dining table with two wine glasses and plates of food, overlooking a historic building at night.

1. Hotel Murillo

Hotel Murillo
2.0 star property
Historical Center
9.0 out of 10, Wonderful, (1,106 reviews)
"The location is perfect the staff is very friendly"
United States
Ronda
The price is ฿3,376
฿3,714 total
includes taxes & fees
2 Nov - 3 Nov
Hotel Murillo
An open-plan dining area with white wicker chairs and tables, a brick wall, and a view of the street through large windows.

2. Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Historical Center
9.6 out of 10, Exceptional, (1,291 reviews)
"Great spot to visit old quarter from"
Australia
simon
The price is ฿4,700
฿5,169 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Amadeus Sevilla
A rooftop terrace with a round table and chairs, a vase of flowers, and a view of historic buildings in the background.

3. Hotel Boutique Casas de Santa Cruz

Hotel Boutique Casas de Santa Cruz
3.0 star property
Historical Center
8.4 out of 10, Very good, (276 reviews)
"Great location, nice room, friendly staff and reasonable pricing. "
Canada
Alice
The price is ฿3,332
฿3,665 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Boutique Casas de Santa Cruz
A rooftop terrace with outdoor seating, a view of historic architecture, and a clear sky.

4. Suites Murillo Catedral

Suites Murillo Catedral
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (749 reviews)
"Beautiful room right in the heart of it all! Loved this place!"
Canada
Marc
The price is ฿4,616
฿5,077 total
includes taxes & fees
18 Nov - 19 Nov
Suites Murillo Catedral
A spacious living area with a sofa, armchairs, a coffee table, and a lamp. There are potted plants and a large painting on the wall.

5. Legado Alcázar Hotel

Legado Alcázar Hotel
4.0 star property
Historical Center
9.8 out of 10, Exceptional, (1,001 reviews)
"Great location and property!"
United States
Shivani
The price is ฿5,461
฿6,008 total
includes taxes & fees
22 Nov - 23 Nov
Legado Alcázar Hotel
A night view of a building with a prominent tower, potted plants, and a balcony.

6. U-Sense Sevilla Centro

U-Sense Sevilla Centro
3.0 star property
Historical Center
9.4 out of 10, Exceptional, (450 reviews)
"Location is perfect. Property is well maintained and rooms were clean. Lots of restaurants around."
Canada
Pratik Anil
The price is ฿4,346
฿4,781 total
includes taxes & fees
27 Oct - 28 Oct
U-Sense Sevilla Centro
A row of multi-story buildings with balconies and large windows.

7. Puerta Catedral Indias Lofts

Puerta Catedral Indias Lofts
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (114 reviews)
"Great location. And the rooftop view in front to cathedral is amazing."
United States
Zhishen
The price is ฿5,822
฿6,404 total
includes taxes & fees
22 Nov - 23 Nov
Puerta Catedral Indias Lofts
A rooftop pool with clear blue water, lounge chairs, and a historic tower in the background.

8. Numa Seville Molina

Numa Seville Molina
3.5 star property
Historical Center
9.4 out of 10, Exceptional, (208 reviews)
"Nice clean spacious apartment. Host was helpful when you could get a hold of her. Lift was out of order for the three days we were there which made lugging up suitcases three flights of stairs as a group of seven a bit hard (it was one of the reasons we chose this place), location was great. Close to everything and in the lovely old part of Seville. Overall we were happy here and would recommend this place (just get the left fixed)."
Australia
Houda
The price is ฿4,647
฿5,111 total
includes taxes & fees
23 Nov - 24 Nov
Numa Seville Molina
A modern building with multiple balconies, large windows, and a clean, white facade.

9. La Posada de los Venerables

La Posada de los Venerables
2.5 star property
Historical Center
9.2 out of 10, Wonderful, (32 reviews)
"The room was clean, the staff was helpful, and we loved the location."
United States
Katherine
The price is ฿3,334
฿3,668 total
includes taxes & fees
23 Nov - 24 Nov
La Posada de los Venerables
A rooftop pool with clear blue water, a person standing on the edge, and a historic tower in the background.

10. Casa Alhaja by Shiadu

Casa Alhaja by Shiadu
3.0 star property
Historical Center
9.8 out of 10, Exceptional, (191 reviews)
"Super clean and relaxing, the rooftop pool was small but mighty- the seville heat is insane lol! Amazing time there and its close to EVERYTHING!"
United States
Carla
The price is ฿5,556
฿6,112 total
includes taxes & fees
5 Nov - 6 Nov
Casa Alhaja by Shiadu
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Cruz Hotel Reviews

Frequently asked questions

How do I find an LGBTQ-friendly hotel in Santa Cruz?
Consider this your open invitation to pack your bags and find Santa Cruz hotels that are members of the International Gay & Lesbian Travel Association on Expedia. Staying in this welcoming area will give you access to its cathedral and cafes.
What is the top LGBTQ-friendly place to stay in Santa Cruz?
Hotel Amadeus Sevilla is a top LGBTQ-friendly hotel that features free Wi-Fi and a rooftop terrace. Hotel Murillo and Casa Alhaja by Shiadu are other good choices for your stay.
How many LGBTQ-friendly accommodation options will I find in Santa Cruz?
You'll find 10 LGBTQ-friendly hotels in Santa Cruz.
What are the top places to visit in Santa Cruz?
During your trip, get out and enjoy everything Santa Cruz has to offer. You and your travelling companions may want to visit Giralda Tower, Convent of the Incarnation and Triunfo Plaza. While you're here, create some great memories of your trip with stops at Puerta del Príncipe, General Archive of the Indies and Hospital de los Venerables.
What is a gay-friendly hotel in Santa Cruz?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. You'll find a selection of LGBTQ-friendly accommodation options on our site. In Santa Cruz, these hotels operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Santa Cruz?
Stay at a gay-friendly hotel in Santa Cruz and you won't have to hide or your sexuality or your gender identity when you check in. Many of our LGBTQ-friendly accommodation options offer community-specific packages, exclusive tours and opportunities for social interaction.

Explore a world of travel with Expedia