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Check prices for these dates

Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

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Our top choices for Santa Cruz Amilpas hotels

A poolside area with lounge chairs and umbrellas, a covered seating area, and a pool.

1. Fiesta Inn Oaxaca

Fiesta Inn Oaxaca
3.5 star property
2.9 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (1,002 reviews)
"Everything was nice and clean Loved the property"
United States
Ignacio
The price is ฿3,430
฿4,082 total
includes taxes & fees
8 Nov - 9 Nov
Fiesta Inn Oaxaca
A modern bedroom with a bed, bedside tables, a chair, and a small table.

2. Maria Ines Hotel Suite

Maria Ines Hotel Suite
3.5 star property
San Agustín de las Juntas, 5.6 km from Santa Cruz Amilpas
9.4 out of 10, Exceptional, (466 reviews)
"The place is very clean great location close to the airport 🛫 very comfortable 👌"
Mexico
BERNARDO
The price is ฿2,137
฿2,544 total
includes taxes & fees
17 Nov - 18 Nov
Maria Ines Hotel Suite
A rooftop pool area with a swimming pool, outdoor seating, and a building with a red dome and a cross on top.

3. Hotel Hacienda

Hotel Hacienda
3.5 star property
3.7 km from Santa Cruz Amilpas
9.0 out of 10, Wonderful, (1,000 reviews)
"Very quaint hotel."
United States
Norma
The price is ฿2,001
฿2,382 total
includes taxes & fees
20 Oct - 21 Oct
Hotel Hacienda
A modern building with a prominent 'One' sign, potted plants, and a curved entrance.

4. One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
Ruta Independencia, 3.8 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (1,001 reviews)
"Clean room, close to restaurant"
United States
Jorge
The price is ฿2,808
฿3,341 total
includes taxes & fees
19 Oct - 20 Oct
One Oaxaca Centro Hotel
A corridor with a yellow wall, a chandelier, potted plants, and a bench.

5. Hotel Doña Alicia

Hotel Doña Alicia
3.0 star property
Reforma, 3.9 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (79 reviews)
"Very comfortable place to stay for a few days."
United States
Wayne
The price is ฿1,504
฿1,790 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Doña Alicia
A hotel room with two beds, a desk, a television, and a minibar.

6. Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG
3.0 star property
Ruta Independencia, 4.6 km from Santa Cruz Amilpas
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room excellent location"
United States
Aivory
The price is ฿3,686
฿4,386 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express Oaxaca-Centro Historico by IHG
A covered outdoor seating area with lounge chairs, a large potted plant, and hanging lanterns.

7. Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
San Felipe del Agua, 5.7 km from Santa Cruz Amilpas
9.2 out of 10, Wonderful, (220 reviews)
"From the check in to the breakfast. staff was very attentive to all our needs from tours to the hotel amenities"
United States
Desiderio
The price is ฿7,271
฿8,653 total
includes taxes & fees
25 Oct - 26 Oct
Casa de Adobe Gallery & Luxury Boutique
A modern bedroom with a bed, a chair, a nightstand, and a starry sky mural on the ceiling.

8. Life Hotel

Life Hotel
3.5 star property
7.5 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (271 reviews)
"Great value, friendly staff, convenient location"
Canada
Orly
The price is ฿2,473
฿2,943 total
includes taxes & fees
19 Oct - 20 Oct
Life Hotel
A pool area with lounge chairs and a pergola.

9. Casa Bonita Hotel & Luxury Residence

Casa Bonita Hotel & Luxury Residence
4.0 star property
San Felipe del Agua, 6.2 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (272 reviews)
"Love the room love the food,loved the taxi services loved the plac"
United States
jimmy william
The price is ฿6,104
฿7,264 total
includes taxes & fees
19 Oct - 20 Oct
Casa Bonita Hotel & Luxury Residence
A swimming pool with lounge chairs, a staircase, and a building with balconies.

10. Hotel Angel Inn

Hotel Angel Inn
3.5 star property
San Felipe del Agua, 6.3 km from Santa Cruz Amilpas
8.6 out of 10, Excellent, (123 reviews)
"Very good experience all way around, we recommend this place 100%"
United States
Josue
The price is ฿2,563
฿3,049 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Angel Inn
A multi-level atrium with wooden paneling, potted plants, and a central seating area with tables and chairs.

11. Hotel Oaxaca Inn Reforma

Hotel Oaxaca Inn Reforma
3.0 star property
Reforma, 4.3 km from Santa Cruz Amilpas
8.2 out of 10, Very good, (80 reviews)
"Great property to stay at"
United States
hugo
The price is ฿2,359
฿2,807 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Oaxaca Inn Reforma
A hotel lobby with a reception desk, a seating area, and a dining space.

12. Hotel Veracruz

Hotel Veracruz
3.0 star property
Jalatlaco, 4.2 km from Santa Cruz Amilpas
8.6 out of 10, Excellent, (199 reviews)
"Verry good place "
United States
Mariano
The price is ฿2,239
฿2,665 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Veracruz
An outdoor patio with steps leading to a seating area, surrounded by a low wall and a tree.

13. City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
Jalatlaco, 3.9 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (853 reviews)
"staff was great"
United States
Fredy
The price is ฿6,015
฿7,158 total
includes taxes & fees
8 Nov - 9 Nov
City Centro by Marriott Oaxaca
A courtyard with a table and chairs under a large umbrella, surrounded by potted plants and a red brick building.

14. Parador Del Dominico

Parador Del Dominico
3.0 star property
Ruta Independencia, 4.1 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (926 reviews)
"Location is great and a the area felt pretty safe"
United States
Cristina
The price is ฿2,711
฿3,226 total
includes taxes & fees
17 Nov - 18 Nov
Parador Del Dominico
A spacious courtyard with columns, outdoor seating, and potted plants.

15. Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
Oaxaca Centro, 4.2 km from Santa Cruz Amilpas
9.4 out of 10, Exceptional, (1,003 reviews)
"Perfect hotel like really PERFECTION"
United States
Curtis
The price is ฿3,699
฿4,401 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Boutique Naura Centro
A spacious lobby with a spiral staircase, a chandelier, and a reception desk.

16. Hotel Trebol

Hotel Trebol
3.0 star property
Oaxaca Centro, 4.5 km from Santa Cruz Amilpas
9.2 out of 10, Wonderful, (1,002 reviews)
"Excellent location, great accommodation, and lovely helpful staff."
United States
Ariadna
The price is ฿3,340
฿3,975 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Trebol
A hotel room with two beds, a desk, a chair, and a wardrobe.

17. Hotel Escalada Suites

Hotel Escalada Suites
3.0 star property
3.4 km from Santa Cruz Amilpas
8.4 out of 10, Very good, (67 reviews)
"Perfect easy place to stay at with a car and closish to major areas."
Canada
Emitt
The price is ฿1,690
฿2,011 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Escalada Suites
An outdoor patio with tables and chairs, umbrellas, and a variety of plants.

18. Happy Express Hotel

Happy Express Hotel
2.5 star property
Oaxaca Centro, 4.8 km from Santa Cruz Amilpas
9.0 out of 10, Wonderful, (406 reviews)
"Staff were attentive and nice. It rained during our stay and when we got out of the taxi the receptionist ran to give us a umbrella. The room was quiet and clean. They give you bottled water which was a plus. Close to mercados and the zocalo which was a plus. Definitely will come again."
United States
jacqueline consuelo
The price is ฿1,669
฿1,986 total
includes taxes & fees
19 Oct - 20 Oct
Happy Express Hotel
A hotel room with a bed, a desk with a sink, a chair, a television, and a window with curtains.

19. City Express by Marriott Oaxaca

City Express by Marriott Oaxaca
3.0 star property
Ruta Independencia, 5 km from Santa Cruz Amilpas
8.6 out of 10, Excellent, (865 reviews)
"My sisters, cousins and I stayed here in August 2026 for a girls trip and had a wonderful experience. A huge highlight was the breakfast buffet which was fresh and had plenty of options. The location is perfect a few minutes from Downtown and surrounded by good local restaurants."
United States
Cristina
The price is ฿2,768
฿3,293 total
includes taxes & fees
19 Oct - 20 Oct
City Express by Marriott Oaxaca
A couple in a hot tub with a decorative tiled wall in the background.

20. Los Olivos Spa

Los Olivos Spa
3.0 star property
Calzada Madero, 6.8 km from Santa Cruz Amilpas
8.4 out of 10, Very good, (204 reviews)
"I love the SPA and the personal is excelent"
United States
Ekizabeth
The price is ฿2,137
฿2,543 total
includes taxes & fees
20 Oct - 21 Oct
Los Olivos Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Cruz Amilpas

Find the best Santa Cruz Amilpas areas for the activities you enjoy most.
A historic cathedral with two prominent towers and a large dome.
Photo by Julie Ruth
Open Photo by Julie Ruth

Oaxaca Centro

Churches, museums and art galleries are some highlights of Oaxaca Centro. Make a stop by Oaxaca Textile Museum or Oaxaca Cathedral while you're exploring.

A historic cathedral with two bell towers and a courtyard with palm trees.
Photo by Sergio Camalich
Open Photo by Sergio Camalich

Ruta Independencia

While visiting Ruta Independencia, you might make a stop by sights like Oaxaca Ethnobotanical Garden and Jardín Etnobotánico.

A narrow cobblestone street flanked by colorful buildings with balconies and hanging plants.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

A colorful sign with the letters "OAKLA" in a public square with a fountain and statues in the background.
Photo by Tahino2000
Open Photo by Tahino2000

Reforma

While visiting Reforma, you might make a stop by sights like Plaza Parque and Plaza Mazari.

An ancient archaeological site with ruins, including stepped pyramids and stone walls, set against a backdrop of mountains and clear skies.
Photo by Rodrigo López
Open Photo by Rodrigo López

Santa Cruz Xoxocotlán

Archaeological sites and cafes are just a few things travellers like about Santa Cruz Xoxocotlán. A stop by Monte Albán is also recommended if you've got time to explore the area.

Top Santa Cruz Amilpas Hotel Reviews

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

10/10 Excellent
"2 cosas, el cuarto no tiene refrigerador, ni plancha, estas 2 cosas son importantes, es un lugar , de muchas bodas.."
Alfredo 7-night trip
Posted 1 hour ago
Hotel Boutique Naura Centro

Frequently asked questions

What is Santa Cruz Amilpas like?
Travellers to the Santa Cruz Amilpas neighbourhood in Oaxaca will be sure to enjoy their stay. Consider a visit to Clases De Karate Do Shito Kai Ittoo Juku as part of your Santa Cruz Amilpas travel plans.
If I need to cancel my hotel reservation in Santa Cruz Amilpas, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals in Santa Cruz Amilpas.
What are the top things to see and do in Santa Cruz Amilpas?
Clases De Karate Do Shito Kai Ittoo Juku is an attraction you might want to check out while you're in Santa Cruz Amilpas. Oaxaca Cultural and Convention Center and A Los Pinos Trailhead are also worth a visit when you're out sightseeing in Oaxaca.