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Our top choices for Sanctuary hotels

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,541 reviews)
"This hotel was really nice and clean."
United States
Lilian
The price is ฿3,369
฿3,757 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Great stay!"
United States
Tamora
The price is ฿3,658
฿4,079 total
includes taxes & fees
26 Jul - 27 Jul
Homewood Suites by Hilton - Fort Myers

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.8 out of 10, Excellent, (887 reviews)
"Friendly staff. Free parking in a safe area.. Excellent location"
United States
Maria
The price is ฿2,972
฿3,314 total
includes taxes & fees
20 Jul - 21 Jul
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.2 out of 10, Very good, (1,234 reviews)
"I have stayed here many times it is clean, reasonably priced and local to the island"
United States
Gabriel
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,149 reviews)
"Great stay"
United States
Marlon
The price is ฿3,652
฿4,072 total
includes taxes & fees
5 Jul - 6 Jul
Doubletree by Hilton Fort Myers at Bell Tower Shops

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,010 reviews)
"Very clean, staff was friendly, and the restaurant downstairs is delicious!"
United States
Carson
The price is ฿2,977
฿3,320 total
includes taxes & fees
5 Jul - 6 Jul
Hilton Garden Inn Ft Myers

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Great hotel"
United States
Cynthia
The price is ฿3,036
฿3,386 total
includes taxes & fees
12 Jul - 13 Jul
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Allure Suites

Allure Suites
3.0 star property
27.2 km from Sanctuary
7.6 out of 10, Good, (1,000 reviews)
"Loved the suite! The space was perfect and comfortable. The staff was super nice as well. The building is old and there are areas where the carpet was stained and the walls were worn, but that did not distract from the room and overall experience. And the price is awesome. I will definitely return."
United States
Nicole
The price is ฿2,852
฿3,180 total
includes taxes & fees
2 Jul - 3 Jul
Allure Suites

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
6.0 out of 10, (1,002 reviews)
"Although the hotel is not new, it is currently being renovated and well maintained. We had a great experience and highly recommend it. The staff were very kind, friendly, and always willing to help. We really enjoyed our stay and would gladly return."
United States
Roger
The price is ฿1,789
฿1,995 total
includes taxes & fees
5 Jul - 6 Jul
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.8 out of 10, Excellent, (1,001 reviews)
"I would stay here again good breakfast nice heated pool good distance to beaches"
United States
Cheryl
The price is ฿3,036
฿3,385 total
includes taxes & fees
28 Jun - 29 Jun
Residence Inn by Marriott Fort Myers Sanibel

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,000 reviews)
"Great location"
United States
Kenneth A.
The price is ฿2,936
฿3,273 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,000 reviews)
"Stayed across the street from the hospital for the birth of my granddaughter. It served its purpose, no frills but accomplished what I needed for my stay."
United States
Matthew
The price is ฿2,235
฿2,492 total
includes taxes & fees
8 Jul - 9 Jul
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
21.5 km from Sanctuary
8.8 out of 10, Excellent, (1,001 reviews)
"The property is beautiful. Great location . Great breakfast and the rooms a great for the price . Will definitely stay there again."
United States
Mercedes
The price is ฿2,807
฿3,130 total
includes taxes & fees
6 Jul - 7 Jul
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (1,000 reviews)
"Nice and clean, friendly staff"
United States
Samuel
The price is ฿4,088
฿4,558 total
includes taxes & fees
27 Jun - 28 Jun
Latitude 26 Waterfront Resort & Marina

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,203 reviews)
"Great place!"
United States
Lucy
The price is ฿3,336
฿3,720 total
includes taxes & fees
28 Jun - 29 Jun
Dolphin Key Resort

Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
22.1 km from Sanctuary
8.8 out of 10, Excellent, (291 reviews)
"Clean room, good location, easy check in instructions."
United States
Brooklyn
The price is ฿1,907
฿3,208 total
includes taxes & fees
27 Jun - 28 Jun
Lazy Cuckoo Inn

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
22.9 km from Sanctuary
8.6 out of 10, Excellent, (1,003 reviews)
"The staff were very helpful.. we enjoyed our stay definitely will be back"
United States
Miriam
The price is ฿3,157
฿3,520 total
includes taxes & fees
16 Jul - 17 Jul
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.6 out of 10, Excellent, (1,001 reviews)
"We had a great experience and would definitely stay here again. Highly recommended for families looking for a relaxing and enjoyable vacation."
United States
NAYLA
The price is ฿8,640
฿10,801 total
includes taxes & fees
5 Jul - 6 Jul
Marriott Sanibel Harbour Resort & Spa

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
21.5 km from Sanctuary
8.6 out of 10, Excellent, (1,690 reviews)
"Great place to stay on the island. Clean, spacious rooms, nice pool, centrally located. Will definitely stay again!"
United States
Cody
The price is ฿4,058
฿5,192 total
includes taxes & fees
29 Jun - 30 Jun
The Lighthouse Resort Inn & Suites

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (2,054 reviews)
"Great place to stay! This was our second time staying here and we will be back again!"
United States
Madison
The price is ฿7,639
฿9,352 total
includes taxes & fees
29 Jun - 30 Jun
Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Sanibel Island Southern Beach and Periwinkle Way are top sights worth seeing.

West End

If you're spending some time in West End, Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Southern Beach and Sanibel Island Northern Beach.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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