San Isidro Packages (Flight + Hotel)

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Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
Madrid Centro

Madrid Centro

4 out of top 10 points of interest in this area
4.5/5(756 area reviews)

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Puerta del Sol and Gran Via, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

Find hotels in Madrid Centro

Top hotels in San Isidro

Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
C/ Gran Via, 84 Madrid
The price is ฿6,188 per night from 10 May to 11 May
฿6,188
฿6,807 total
10 May - 11 May
includes taxes & fees
9.4/10 Exceptional! (4,819 reviews)
Rude staff: The hotel's rooftop bar is open to the public and - by the staffs' own comments - have had issues with unpleasant "clientele" (not paying bar tabs, restaurant bill etc). You can expect to be interrogated by doormen whether you're actually staying at the hotel, be required to pay the food ...

Reviewed on 5 May 2026

Hotel Riu Plaza España
Novotel Madrid Center

Novotel Madrid Center

4 out of 5
O'donnell 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
The price is ฿8,124 per night from 25 May to 26 May
฿8,124
฿8,936 total
25 May - 26 May
includes taxes & fees
9.2/10 Wonderful! (1,181 reviews)
Good location

Reviewed on 5 May 2026

Novotel Madrid Center
Hotel Regina

Hotel Regina

4 out of 5
Alcala 19 Madrid Madrid
Fully refundableReserve now, pay when you stay
The price is ฿6,588 per night from 10 May to 11 May
฿6,588
฿7,247 total
10 May - 11 May
includes taxes & fees
9.8/10 Exceptional! (2,301 reviews)
Super clean hotel and room. The breakfast was delicious, with a big variety of choices.

Reviewed on 5 May 2026

Hotel Regina
See all 6,216 properties in San Isidro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Isidro holiday package cost?
Tailor make your San Isidro package from only . Pick from any combination of hotels, flights and rental cars to craft the trip of your dreams. Remember to add on a few experiences or tours!
How do I get a cheap travel package to San Isidro?
One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got them all. Select the combination that suits your style and watch your savings pile up. Of course, a travel package is never one-size-fits-all. That's why we offer more than 550 airlines and 1,000,000 hotel options from all over the world, which lets you customize your San Isidro holiday.
Where should I stay in San Isidro?
Most travellers who visit San Isidro put both Plaza Mayor and Prado Museum on their bucket lists. Why not go for a hotel near these popular attractions?
What are the top hotels in San Isidro?
If it's your first time in San Isidro, make a reservation at Apartment With 2 Bedrooms In Madrid or Cielo Madrid Studios. Both hotels offer comfortable beds and are popular options with many savvy travellers.
How far in advance should I book my San Isidro holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise tickets up to 12 months prior to departure dates. This is typically the cheapest time to book. If circumstances have left you booking late, fantastic last-minute deals to San Isidro will sometimes occur just weeks before departure.
What does an Expedia San Isidro travel package include?
From airfares and hotels to rental cars, Expedia can help you shape a San Isidro package that fits you. Heading away for a while? Look into a flight, hotel and rental car bundle. If you can only manage a quick getaway, a hotel and airfare deal could be what you're after. Experiences can also be added after you've booked. Our holiday packages make it simple to save and plan.
What should I know before booking a San Isidro travel package?
You'll enjoy great savings when you bundle your flights, hotels and rental cars into a package. Not just that, booking everything together will make your trip planning easier. So why waste time or money? Whether you're putting together a ritzy romantic getaway or a low-cost family road trip, have a look at our holiday packages today.
Can I choose my airline with a San Isidro Expedia holiday package?
You certainly can. Expedia has access to more than 550 airline partners throughout the world, so select the carrier that fits your budget and travelling style.
If I'm not able to travel, can I cancel my San Isidro holiday package?
We understand — life doesn't always go according to plan. If you've locked in a San Isidro holiday package and need to cancel or change it, we're here to help. We recommend checking out our Customer Service Portal first for information. But generally speaking, if you've booked your package within 24 hours, you may be able to cancel or change your itinerary free of charge. If it's been more than 24 hours, your airline, hotel or car rental company may charge a fee.

Popular places to visit

Gran Via

Gran Via

Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture.

Gran Via
Puerta del Sol

Puerta del Sol

Stand at the very center of Madrid and feel the buzz as thousands of people meet and greet before a night out, gather for protests, or start out on a tour of the city.

Puerta del Sol
Plaza Mayor

Plaza Mayor

This square has seen everything from markets and public celebrations to bullfights and executions. Today you’ll find street performers, artists and plenty of shops.

Plaza Mayor

Things to do

Red double-decker hop-on hop-off bus in Madrid

Madrid City Tour – Hop On Hop Off Bus

฿1,178
per adult
80% of travellers recommend
Madrid City Tour – Hop On Hop Off Bus
Skip-the-Line with Madrid’s Royal Palace Expert Guided Tour

Madrid: Royal Palace Expert Guided Tour with Optional Tapas

฿1,319
per adult
94% of travellers recommend
Madrid: Royal Palace Expert Guided Tour with Optional Tapas
Big Bus Madrid Panoramic Open-top Bus Tour

Big Bus Madrid Hop-on, Hop-off Open-top Sightseeing Bus Tour

฿781
per adult
82% of travellers recommend
Big Bus Madrid Hop-on, Hop-off Open-top Sightseeing Bus Tour
See all activities in Madrid
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.