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OYO Inn & Suites Medical Center San Antonio

2.0 star property
Travelers find convenient self-parking and a relaxing atmosphere at this San Antonio hotel, perfectly positioned for visits to the nearby zoo or aquarium

Choose dates to view prices

OYO Inn & Suites Medical Center provides a comfortable base in the heart of San Antonio. Guests connect to WiFi and take advantage of extended parking while staying near South Texas Medical Center, Wonderland of the Americas Mall, and the San Antonio Zoo and Aquarium.

Reviews

7.4 out of 10
Good

Popular amenities

  • Parking included
  • Air-conditioning
  • Room service
  • Housekeeping
  • 24/7 front desk
The current price is ΰΈΏ1,846
ΰΈΏ2,340 total
includes taxes & fees
10 Jul - 11 Jul

Room options

Available filters for rooms
Showing 7 of 7 rooms

View all photos for Premium King Bed

A hotel room with a bed, a desk, a chair, a window, and a door.

Premium King Bed

  • Sleeps 2

View all photos for King Bed

A hotel room with a bed, bedside lamps, a window, and a television.

King Bed

  • Sleeps 2

View all photos for 2 Queen Bed

A hotel room with two beds, a TV, a desk with a computer, and a window with curtains.

2 Queen Bed

  • Sleeps 4

View all photos for Room, 2 Queen Beds

Room, 2 Queen Beds | Desk, iron/ironing board, Internet, bed sheets

Room, 2 Queen Beds

  • 22 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed

Desk, iron/ironing board, Internet, bed sheets

Room, 1 King Bed

9.4 out of 10
Exceptional
(12 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Premium Room, 1 King Bed

Desk, iron/ironing board, Internet, bed sheets

Premium Room, 1 King Bed

  • 21 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Smoking

Desk, iron/ironing board, Internet, bed sheets

Room, 1 King Bed, Smoking

7.0 out of 10
Good
(2 reviews)
  • 20 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

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About the area

Located in Medical Center District, a neighbourhood in San Antonio, OYO Inn & Suites Medical Center San Antonio is in the entertainment district and near the airport. Wonderland of the Americas Mall is worth exploring if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit San Antonio Zoo and Aquarium and San Antonio Botanical Gardens. Don't miss out on a visit to Six Flags Fiesta Texas. Visit our San Antonio travel guide
View more Motels in San Antonio
Map
3782 NW Loop 410, San Antonio, TX, 78229

What's nearby

  • River Walk
    River Walk
    11 min drive - 15.4 km
  • The Alamo in San Antonio, Texas, USA.
    Alamo
    12 min drive - 19.2 km
  • Wonderland of the Americas Mall
    7 min walk - 0.6 km
  • First Unitarian Universalist Church
    1 min drive - 1.9 km
  • Oak Hills Country Club
    4 min drive - 1.9 km

Getting around

  • San Antonio Station
    17 min drive
  • Victoria, TX (VCT-Victoria Regional)
    138 min drive

Restaurants

  • QuikTrip
    7 min walk
  • Chick-fil-A
    11 min walk
  • Whataburger
    10 min walk
  • Dave & Buster's
    13 min walk
  • Babe's Old Fashioned Hamburgers
    8 min walk

About this property

OYO Inn & Suites Medical Center San Antonio

  • Motel near South Texas Medical Center
  • Located close to Wonderland of the Americas Mall and San Antonio Zoo and Aquarium, OYO Inn & Suites Medical Center San Antonio has plenty to offer. Guests can connect to free WiFi in public areas.
  • You'll also enjoy the following perks during your stay:
    • Free self-parking
    • A vending machine and a 24-hour front desk
  • Room features
  • All guest rooms at OYO Inn & Suites Medical Center San Antonio have comforts, such as air conditioning, as well as
  • Other conveniences in all rooms include:
    • Bathrooms with showers and free toiletries
    • 32-inch flat-screen TVs with cable channels
    • Mini fridges, microwaves and daily housekeeping

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Property amenities

Internet

  • Available in all rooms: High-speed internet
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Free RV/bus/lorry parking on site
  • Limited on-site self parking

Family friendly

  • In-room microwave
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Vending machine

Guest services

  • Housekeeping (daily)

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Grab bar near toilet (89 centimetre high)
  • No lift

More

  • 1 building
  • 2 floors
  • Designated smoking areas

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower
  • Toilet paper
  • Towels provided

Entertainment

  • 32-inch flat-screen TV with cable channels

Food and drink

  • Limited room service
  • Microwave
  • Mini-fridge

More

  • Air conditioning
  • Desk
  • Free local calls
  • Iron/ironing board
  • Phone

Policies

Check-in

Check-in time starts at 3:00 PM
Early check-in subject to availability
Early check-in is available for a fee
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Late check-out subject to availability
A late check-out fee will be charged

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
1 child, up to the age of 17 years, can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Deposit: USD 50 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Early check-in is available for a fee (subject to availability)
  • Late check-out is available for a fee (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards and cash
Safety features at this property include a fire extinguisher, a smoke detector and a first aid kit

We should mention

This property does not have any lifts
Alcohol is not served at this property
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is OYO Inn & Suites Medical Center San Antonio pet-friendly?

No, only service animals are welcome at the property.

How much does it cost to stay at OYO Inn & Suites Medical Center San Antonio?

As of 22 Jun 2026, prices found for a 1-night stay for 2 adults at OYO Inn & Suites Medical Center San Antonio on 10 Jul 2026 start from ΰΈΏ1,846, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at OYO Inn & Suites Medical Center San Antonio?

Self-parking is free at this property.

What time is check-in at OYO Inn & Suites Medical Center San Antonio?

Check-in begins at 3:00 PM. A fee applies for early check-in (subject to availability).

What time is check-out at OYO Inn & Suites Medical Center San Antonio?

Checkout is at 11 AM. Late check-out is available for a fee (subject to availability).

Where is OYO Inn & Suites Medical Center San Antonio located?

Located in Medical Center District, this motel is 0.3 mi (0.5 km) from Wonderland of the Americas Mall and 2.7 mi (4.4 km) from South Texas Medical Center. San Antonio Zoo and Aquarium and River Walk are also within 9 mi (15 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

OYO Inn & Suites Medical Center San Antonio Reviews

7.4

Good

7.2

Cleanliness

7.4

Location

7.8

Staff & service

7.0

Property conditions & facilities
Rating 10 - Excellent. 96 out of 239 reviews
Rating 8 - Good. 52 out of 239 reviews
Rating 6 - Okay. 30 out of 239 reviews
Rating 4 - Poor. 25 out of 239 reviews
Rating 2 - Terrible. 36 out of 239 reviews

Reviews

Verified

10/10 Excellent

Ronnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was quiet and clean and the staff was very friendly
Stayed 1 night in May 2026
Verified

8/10 Good

Thomas

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was courteous and professional and the room is nice.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Thomas

Liked: Cleanliness, amenities, property conditions & facilities
The staff was courteous, and professional and the room was very good.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Archie

Liked: Cleanliness, staff & service, amenities
Excellent property!! Staff were very kind.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Carlos

Liked: Cleanliness, amenities, property conditions & facilities
Staff was friendly and helpful, with no issues checking-in.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Quiet area
Stayed 7 nights in Apr 2025
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, property conditions & facilities
Safe quite easily accessible
Stayed 1 night in Oct 2023
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, property conditions & facilities
Quite and comfortable
Stayed 1 night in Oct 2023
Verified

10/10 Excellent

Jesse

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was comfortable
Stayed 1 night in Oct 2024
Verified

10/10 Excellent

Santos

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My husband and son had a great stay it was close to the UT HOSPITAL so it was great for my family to come see me during my stay. The floor was a little dingy but it's expected with an older hotel.
Stayed 2 nights in Nov 2023
Verified

10/10 Excellent

Jilaine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The gentleman at front was pleasant, caring, friendly. Rooms clean! Great experience will return when in area
Stayed 1 night in Sep 2023
Verified

6/10 Okay

Karen

Ok. The manager seemed understated, quiet, easy going. When he ran my card tho, he listed hotel as Country Hearth or some such and my card auto declined having nothing to do with me. Used my debit card. Area appeared safe off 410. Room was so so. Holes in bedspread, holes in curtain. Cracks in granite sink. My drink froze in fridge overnite.teied to thaw in microwave, but then it was too watery. Tub had what appeared to be cigarette burns on edge. But major problem was that the towels and washcloths were dingy and not fluffy. Past Time to replace these!!
Verified

6/10 Okay

Kenneth

Liked: Staff & service
Disliked: Property conditions & facilities
Here is the positive before the negative. I give 3 out of 5 stars due to: 1. The staff was friendly 2. Was a quick check-in 3. The water was hot 4. The bed & pillows were comfort 5. TV, fridge, microwave worked 6. Ice maker worked. Negative was the towels had stains on them,we had to ask for clean ones. The shower curtain had stains on them as well. The toilet seat was not secure. Needed fixing. The grounds need cleaning, the doors have pealing paint as well the rest of the building and stairs need paint. The cost per room was very cheap so I guess you get what you pay for. If your staying a night in San Antonio and on a budget, this place would be fine for you. Next time for me I will pay more for more cleanliness elsewhere.
Stayed 2 nights in Mar 2024
Verified

10/10 Excellent

Laura

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean, respectful staff hotel room was very beautiful cleaned most definitely will be returning
Stayed 1 night in Apr 2026
Verified

8/10 Good

Tonya

Liked: Cleanliness, staff & service, property conditions & facilities
I appropriated their accommodation to give us a bottom floor room (back problems)
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Juan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always great stay
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Wilfredo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful place to stay love it
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Wilfredo

Liked: Staff & service, amenities, property conditions & facilities
Nice place to stay lovely
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Wilfredo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a beautiful place to stay lovely 😍
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Wilfredo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a beautiful place to stay ❀️ πŸ’–
Stayed 1 night in Mar 2025
Verified

10/10 Excellent

Olga

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Was good last minute trip thanks
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Olga

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The location is great the staff were very nice the room was very agreeable thanks
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a wonderful stay.
Stayed 1 night in Jan 2023
Verified

10/10 Excellent

Buffy

Liked: Cleanliness
Was a great little place
Stayed 1 night in Oct 2024
Verified

10/10 Excellent

Wilfredo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I love this place lovely
Stayed 1 night in Feb 2025