What's it like in Uptown Central?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown Central neighbourhood has to offer. Are you looking for Uptown Central travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.

What's the best accommodation in Uptown Central?

Based on our traveller data, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is one of the top choices for your stay in Uptown Central. This hotel is a short 14-minute walk from North Star Mall, and it offers free breakfast and an outdoor pool. Other good options for your stay in the area include Wyndham Garden San Antonio Airport and La Quinta Inn & Suites by Wyndham San Antonio Airport .

How many hotels will I be able to find in the Uptown Central area?

Expedia has 392 hotels and other accommodation options in Uptown Central to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown Central, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown Central.

What can I see and do in this San Antonio neighbourhood?

Uptown Central's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown Central include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and Gayle and Tom Benson Stadium are also worth a visit when you're out sightseeing in San Antonio.

The Best Hotels in Uptown Central, San Antonio - 2026 Updated Prices

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Our top choices for Uptown Central hotels

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1. Holiday Inn Express San Antonio-Airport by IHG

Uptown Central

Lori

฿4,199 total

includes taxes & fees

29 Oct - 30 Oct

A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

2. Drury Plaza Hotel San Antonio Airport

Uptown Central

Darlene

฿4,559 total

includes taxes & fees

25 Oct - 26 Oct

A modern bar area with seating and a staircase leading to an upper level.

3. Embassy Suites by Hilton San Antonio Airport

Uptown Central

Trenton

฿5,051 total

includes taxes & fees

1 Nov - 2 Nov

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

4. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central

Amy

฿3,162 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with a dark blue sofa, four grey armchairs, and three metallic coffee tables.

5. La Quinta Inn & Suites by Wyndham San Antonio Airport

Uptown Central

Vanesa

฿3,167 total

includes taxes & fees

25 Oct - 26 Oct

A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

6. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Uptown Central

Lauro

฿5,051 total

includes taxes & fees

15 Nov - 16 Nov

A modern living room with a sofa, coffee table, and a large abstract painting.

7. Marriott San Antonio Airport

Uptown Central

Erika

฿4,473 total

includes taxes & fees

14 Nov - 15 Nov

A modern kitchen with a central island, built-in appliances, and a coffee station.

8. Wyndham Garden San Antonio Airport

Uptown Central

Johnny

฿3,366 total

includes taxes & fees

1 Nov - 2 Nov

A modern interior with a curved ceiling, a sectional sofa, a round coffee table, and a dining area with chairs and a table.

9. SpringHill Suites by Marriott San Antonio Airport

Uptown Central

jennifer

฿3,582 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with metal chairs, a barbecue grill, and string lights.

10. Home2 Suites by Hilton San Antonio Airport, TX

Uptown Central

Darlene

฿4,231 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a central island, a refrigerator, and a coffee machine.

11. Staybridge Suites San Antonio by IHG

Uptown Central

riccara

฿3,672 total

includes taxes & fees

16 Nov - 17 Nov

A modern bar area with a long counter, multiple bar stools, and a television screen.

12. Courtyard by Marriott San Antonio Airport

Uptown Central

Rory

฿3,564 total

includes taxes & fees

31 Oct - 1 Nov

A breakfast bar with various food items and kitchen appliances.

13. Spark by Hilton San Antonio Airport

Uptown Central

Brian

฿2,850 total

includes taxes & fees

28 Oct - 29 Oct

A buffet area with a variety of food options, a beverage dispenser, and a fruit bowl.

14. Fairfield Inn & Suites San Antonio Airport/North Star Mall

Uptown Central

Bridget

฿3,046 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

15. Crowne Plaza San Antonio Airport by IHG

Uptown Central

Zachary

฿2,840 total

includes taxes & fees

27 Oct - 28 Oct

A hotel lobby with a reception desk, seating area with sofas and chairs, and a patterned carpet.

16. TownePlace Suites by Marriott San Antonio Airport

Uptown Central

Alejandro

฿4,283 total

includes taxes & fees

28 Oct - 29 Oct

A spacious lobby with a beige sofa, a chandelier, a staircase, and a large window overlooking a parking area.

17. Days Inn by Wyndham San Antonio Airport

Uptown Central

LUCERO

฿2,313 total

includes taxes & fees

27 Oct - 28 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

18. Residence Inn By Marriott San Antonio Airport/Alamo Heights

Uptown Central

Jill

฿4,999 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a sofa, a round table, a bed, a lamp, and a window with curtains.

19. Comfort Suites San Antonio North - Stone Oak

Uptown Central

Kalkidan

฿2,966 total

includes taxes & fees

11 Nov - 12 Nov

A modern bar area with a wooden counter, a beverage dispenser, and a coffee machine.

20. Courtyard by Marriott San Antonio Airport/North Star Mall

Uptown Central

Osvaldo

฿3,437 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Compare popular hotels in Uptown Central

Property	Property class	Guest rating
Holiday Inn Express San Antonio-Airport by IHG	2.5 star property	9.4 Exceptional 1,006 reviews	View
Drury Plaza Hotel San Antonio Airport	3.0 star property	9.4 Exceptional 2,318 reviews	View
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham	2.5 star property	9.0 Wonderful 2,320 reviews	View
Spark by Hilton San Antonio Airport	2.0 star property	8.8 Excellent 1,850 reviews	View
Estancia del Norte San Antonio, Tapestry Collection by Hilton	3.5 star property	9.0 Wonderful 1,000 reviews	View

Where to stay in Uptown Central

Find the best Uptown Central areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

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Top Uptown Central Hotel Reviews

Omni La Mansion del Rio

10/10 Excellent

"Best hotel ever"

Red Roof Inn San Antonio - Airport

10/10 Excellent

"On my first run through San Antonio on my fall 2026 trip, I stayed at Quality Inn and Suites on 281, which was a bad experience, so I checked reviews more carefully for my San Antonio stay on my return trip, and this place had good reviews (and was close to the airport), so I decided to try it. It was a good choice. It was the same price as Quality Inn, but cleaner. I was quite tired when I got here and had a short night, so I don’t remember many details about it, but I don’t remember being dissatisfied with anything. The bed was good, the bathroom was fine, and a plus for me is that there was no carpet on the floor — I find hotel carpets to be gross. The room had a large desktop with a chair that looked comfortable. (I forgot to get a picture of that.) If you want a cheap hotel, especially one close to the airport, I would recommend this one."

Search Hotels in Uptown Central, San Antonio

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Our top choices for Uptown Central hotels

1. Holiday Inn Express San Antonio-Airport by IHG

2. Drury Plaza Hotel San Antonio Airport

3. Embassy Suites by Hilton San Antonio Airport

4. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

5. La Quinta Inn & Suites by Wyndham San Antonio Airport

6. Estancia del Norte San Antonio, Tapestry Collection by Hilton

7. Marriott San Antonio Airport

8. Wyndham Garden San Antonio Airport

9. SpringHill Suites by Marriott San Antonio Airport

10. Home2 Suites by Hilton San Antonio Airport, TX

11. Staybridge Suites San Antonio by IHG

12. Courtyard by Marriott San Antonio Airport

13. Spark by Hilton San Antonio Airport

14. Fairfield Inn & Suites San Antonio Airport/North Star Mall

15. Crowne Plaza San Antonio Airport by IHG

16. TownePlace Suites by Marriott San Antonio Airport

17. Days Inn by Wyndham San Antonio Airport

18. Residence Inn By Marriott San Antonio Airport/Alamo Heights

19. Comfort Suites San Antonio North - Stone Oak

20. Courtyard by Marriott San Antonio Airport/North Star Mall

Compare popular hotels in Uptown Central

Where to stay in Uptown Central

Downtown San Antonio

Far West Side

Medical Center District

Northwest Side

Stone Oak

Top Uptown Central Hotel Reviews

Omni La Mansion del Rio

Frequently asked questions

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